Granulomatous and suppurative dermatitis at interferon alfa injection sites: report of 2 cases.

Abstract:

:It has previously been reported that interferon alfa injection sites may develop pyoderma gangrenosum, interface dermatitis, vasculitis, or, more commonly, ulcers characterized by intravascular thrombi and a mixed inflammatory cell infiltrate. We describe 2 patients in whom granulomatous and suppurative dermatitis developed at interferon alfa injection sites. These cases extend the spectrum of interferon alfa injection site reactions. The histologic and clinical similarities of these cases with pyoderma gangrenosum and cutaneous Crohn's disease are explored.

journal_name

J Am Acad Dermatol

authors

Sanders S,Busam K,Tahan SR,Johnson RA,Sachs D

doi

10.1067/mjd.2002.119087

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

611-6

issue

4

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(02)68976-5

journal_volume

46

pub_type

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