Abstract：
BACKGROUND:Topical immunotherapy has been used in the treatment of children with alopecia areata with encouraging results. OBJECTIVE:Our purpose was to determine the long-term results in 33 children with severe alopecia areata treated with topical immunotherapy. METHODS:From 1983 to 1989 we treated 33 children with topical immunotherapy with squaric acid dibutylester. RESULTS:Complete hair regrowth was observed in 10 children (30.3%). During the follow-up period (mean, 5.9 years; range, 4 to 12 years), 7 of these 10 patients had severe relapses that were not responsive to further treatment. Only three clinically benefited from topical immunotherapy. Two maintained complete hair regrowth after treatment was stopped. CONCLUSION:Our results indicate that only a small proportion of children with severe alopecia areata will obtain a persistent benefit from topical immunotherapy.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Tosti A,Guidetti MS,Bardazzi F,Misciali Cdoi
10.1016/s0190-9622(96)90323-0subject
Has Abstractpub_date
1996-08-01 00:00:00pages
199-201issue
2 Pt 1eissn
0190-9622issn
1097-6787pii
S0190-9622(96)90323-0journal_volume
35pub_type
杂志文章abstract：:The analysis of population-specific human leukocyte antigen (HLA) haplotypes has provided evidence that susceptibility to psoriasis is linked to the class I and II major histo-compatibility complex on human chromosome 6. In addition, these studies show that psoriasis consists of two distinct disease subtypes (type I a...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：
更新日期：1997-08-01 00:00:00
abstract：BACKGROUND:Necrolytic migratory erythema (NME) is an uncommon inflammatory dermatosis with a distinct clinical and histologic appearance. NME is usually associated with glucagonoma. Only a few cases of NME in the absence of glucagonoma have been previously reported. OBJECTIVE:We sought to understand further the pathog...
journal_title：Journal of the American Academy of Dermatology
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doi：10.1016/0190-9622(95)90345-3
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abstract：BACKGROUND:Although most patients with cutaneous melanoma are non-Hispanic whites (NHWs), minorities consistently suffer worse melanoma-specific survival (MSS). Much of the literature comes from analyses of registries from the 1990s and 2000s. OBJECTIVE:We sought to evaluate whether and to what degree racial disparity...
journal_title：Journal of the American Academy of Dermatology
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abstract：BACKGROUND:Accurate evaluation of basal cell carcinoma (BCC) in the United States was not possible before the 2011 release of BCC-specific International Classification of Diseases, Ninth Revision, Clinical Modification codes. OBJECTIVE:We sought to describe BCC (including locally advanced BCC [LABCC]) incidence/preval...
journal_title：Journal of the American Academy of Dermatology
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abstract：BACKGROUND:Glomangiomas are benign tumors arising from neuromyoarterial cells surrounding cutaneous arteriovenous anastomoses that serve as temperature regulators. They exist as solitary or multiple types, occurring sporadically or in a familial pattern, the latter of which is rare. OBJECTIVE:We describe a 4-generatio...
journal_title：Journal of the American Academy of Dermatology
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doi：
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Little is known about the utilization of medical services for psoriasis. OBJECTIVE:Our purpose was to quantify the medical resources utilized in the United States for the treatment of psoriasis. METHODS:By utilizing data tapes from the National Center of Health Statistics we estimated the number of outpati...
journal_title：Journal of the American Academy of Dermatology
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doi：10.1016/s0190-9622(96)90676-3
更新日期：1996-10-01 00:00:00
abstract：CAPSULE SUMMARY:In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. ...
journal_title：Journal of the American Academy of Dermatology
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abstract：BACKGROUND:Submissions to the Journal of the American Academy of Dermatology (JAAD) undergo a rigorous peer-review process. However, little is known regarding the fate of manuscripts declined by the JAAD. OBJECTIVE:We sought to: (1) determine the proportion of manuscripts declined by the JAAD that are subsequently pub...
journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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abstract：BACKGROUND:Complications associated with psoriatic arthritis (PsA) may be prevented with early diagnosis and initiation of therapy. Up to one third of psoriasis patients may have PsA. There is a need to screen psoriasis patients early for symptoms of PsA. OBJECTIVE:To develop and validate a patient self-administered t...
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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更新日期：2011-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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abstract：:Palpable purpura in a follicular localization developed in association with acute epididymitis in a white man who was seropositive for the human immunodeficiency virus (HIV). Biopsy specimens revealed a leukocytoclastic vasculitis with follicular accentuation. With antibiotic therapy the vasculitis resolved, but it re...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
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更新日期：1991-05-01 00:00:00
abstract：:A combination of topical and oral antifungals is widely used to treat onychomycosis, but treatment failure is common and oral drugs may cause toxicity and potential drug interactions. For this reason, new approaches and strategies should be considered. The following case shows that photodynamic therapy (PDT) may repre...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
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更新日期：2008-11-01 00:00:00
