Metabolic costs of force generation for constant-frequency and catchlike-inducing electrical stimulation in human tibialis anterior muscle.

Abstract:

:Metabolic costs of force generation were compared for constant-frequency and catchlike-inducing electrical stimulation. Repetitive catchlike-inducing trains consisted of 2 interpulse intervals (IPIs) at 12.5 ms, 1 IPI at 25 ms, and 5 IPIs at 50 ms. Constant-frequency trains consisted of 8 IPIs at 37.5 ms. One train was delivered to the peroneal nerve every 2.5 s for 36 times under ischemic conditions. Anaerobic adenosine triphosphate (ATP) turnover was determined using 31-phosphorus magnetic resonance spectroscopy (P-MRS) of the human tibialis anterior muscle. Compared with constant-frequency trains, catchlike-inducing trains produced a faster force generation and were more effective in maintaining the force--time integral as well as peak force. However, ATP costs of force generation were similar for the catchlike-inducing and constant-frequency stimulation (6.7 plus/minus 1.1 and 6.6 plus/minus 1.0 micromol ATP/kg wet weight/Ncenter dots, respectively, P = 0.601). This suggests that the positive effects of catchlike-inducing stimulation on force maintenance are mediated by potentiated Ca(2+) release from the sarcoplasmic reticulum rather than by lower metabolic costs of muscle force generation. Our findings also suggest that catchlike-inducing stimulation produces larger forces in fatigued muscle than constant-frequency trains and thus may be beneficial for muscle training or rehabilitation when muscle loading needs to be maintained in repetitive contractions.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Ratkevicius A,Quistorff B

doi

10.1002/mus.10064

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

419-26

issue

3

eissn

0148-639X

issn

1097-4598

pii

10.1002/mus.10064

journal_volume

25

pub_type

杂志文章
  • The electrodiagnostic findings in polyneuropathies associated with IgM monoclonal gammopathies.

    abstract::Electrodiagnostic studies were analyzed in patients with neuropathy associated with IgM monoclonal proteins, 7 with anti-myelin associated glycoprotein reactivity (MAG) and 7 nonreactive to MAG. The findings were distinctly different in the two groups. The electrodiagnostic studies of all the MAG-reactive patients had...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880131205

    authors: Kelly JJ Jr

    更新日期:1990-12-01 00:00:00

  • Amyotrophic lateral sclerosis-Evolutionary and other perspectives.

    abstract::In this study some particular and puzzling aspects of amyotrophic lateral sclerosis (ALS) are discussed, with an emphasis on the role of neocortical evolution. Other issues explored include the nature of the clinical deficit in ALS; anatomical and evolutionary aspects of the neocortex, motor cortex, and corpus callosu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21404

    authors: Eisen A

    更新日期:2009-08-01 00:00:00

  • Comparing the force- and excursion- frequency relationships in human skeletal muscle.

    abstract::We examined the influence of varying stimulation frequency on muscle output during isometric and dynamic contractions. Our findings demonstrate that the predictability of the force- and excursion-frequency relationships is extremely strong across stimulation intensities. There were no differences in the frequency whic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21161

    authors: Gregory CM,Bickel CS,Sharma N,Dixon WE

    更新日期:2008-12-01 00:00:00

  • A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region.

    abstract:INTRODUCTION:Nebulin is a giant actin-binding protein in the thin filament of the skeletal muscle sarcomere. Studies of nebulin interactions are limited by the size, complexity, and poor solubility of the protein. We divided the nebulin super-repeat region into a super-repeat panel, and studied nebulin/actin interactio...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26350

    authors: Laitila J,Lehtonen J,Lehtokari VL,Sagath L,Wallgren-Pettersson C,Grönholm M,Pelin K

    更新日期:2019-01-01 00:00:00

  • Paradoxical sleep deprivation induces muscle atrophy.

    abstract:INTRODUCTION:Because paradoxical sleep deprivation (PSD) induces a catabolic hormone profile, we sought to evaluate the morphology of the tibialis anterior (TA) muscle and testosterone and corticosterone levels of paradoxical sleep-deprived rats. METHODS:Three study groups of rats were established: the first group was...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22322

    authors: Dattilo M,Antunes HK,Medeiros A,Mônico-Neto M,Souza Hde S,Lee KS,Tufik S,de Mello MT

    更新日期:2012-03-01 00:00:00

  • Parenteral branched-chain amino acid treatment and avian dystrophy.

    abstract::Genetically homozygous line 413 dystrophic chickens were given twice-daily intraperitoneal injections of solutions containing branched-chain amino acids (BCCA-leucine, valine, isoleucine) either alone or in combination; and their alpha-ketoacid analogs (alpha-ketoisocaproic and alpha-ketoisovaleric acids). Another tri...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880050606

    authors: Hudecki MS,Pollina CM,Heffner RR

    更新日期:1982-07-01 00:00:00

  • Pathophysiology of spastic paresis. I: Paresis and soft tissue changes.

    abstract::Spastic paresis follows chronic disruption of the central execution of volitional command. Motor function in patients with spastic paresis is subjected over time to three fundamental insults, of which the last two are avoidable: (1) the neural insult itself, which causes paresis, i.e., reduced voluntary motor unit rec...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.20284

    authors: Gracies JM

    更新日期:2005-05-01 00:00:00

  • Endocannabinoids and related lipids in serum from patients with amyotrophic lateral sclerosis.

    abstract:BACKGROUND:The goals of this study were to determine whether serum concentrations of endocannabinoids (eCB) and related lipids predict disease status in patients with amyotrophic lateral sclerosis (ALS) relative to healthy controls, and whether concentrations correlate with disease duration and severity. METHODS:Serum...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.27096

    authors: Carter GT,McLaughlin RJ,Cuttler C,Sauber GJ,Weeks DL,Hillard CJ,Weiss MD

    更新日期:2021-01-01 00:00:00

  • Application of differentiated human tonsil-derived stem cells to trembler-J mice.

    abstract:INTRODUCTION:Mesenchymal stem cells (MSCs) can differentiate into various cell types. METHODS:In this study we investigated the potential of human tonsil-derived MSCs (T-MSCs) for neuromuscular regeneration in trembler-J (Tr-J) mice, a model for Charcot-Marie-Tooth disease type 1A (CMT1A). RESULTS:T-MSCs differentiat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25763

    authors: Park S,Choi Y,Kwak G,Hong YB,Jung N,Kim J,Choi BO,Jung SC

    更新日期:2018-03-01 00:00:00

  • Did giant mitochondria delay muscle maturation? An uncommon congenital myopathy.

    abstract:INTRODUCTION:Mitochondria are semi-autonomous organelles that are able to change their shape, size, location, and number inside the living cell. Mitochondrial division is an extremely important process, because cell survival depends on there being an adequate number of mitochondria in each cell. The dynamics of these o...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23365

    authors: Fidziańska A,Glinka Z

    更新日期:2012-07-01 00:00:00

  • Electrical impedance myography in the diagnosis of radiculopathy.

    abstract:INTRODUCTION:We sought to determine whether electrical impedance myography (EIM) could serve as a diagnostic procedure for evaluation of radiculopathy. METHODS:Twenty-seven patients with clinically and radiologically diagnosed cervical or lumbosacral radiculopathy who met a "gold standard" definition underwent EIM and...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23833

    authors: Spieker AJ,Narayanaswami P,Fleming L,Keel JC,Muzin SC,Rutkove SB

    更新日期:2013-11-01 00:00:00

  • Nerve ultrasound identifies abnormalities in the posterior interosseous nerve in patients with proximal radial neuropathies.

    abstract:INTRODUCTION:The radial nerve and posterior interosseous nerve (PIN) are prone to injury at multiple sites. Electrodiagnostic (EDx) studies may only identify the most proximal lesion. Nerve ultrasound could augment EDx by visualizing additional pathology. METHODS:This investigation was a retrospective examination of u...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24778

    authors: Dietz AR,Bucelli RC,Pestronk A,Zaidman CM

    更新日期:2016-03-01 00:00:00

  • Ultrasound appears to be a reliable technique for the diagnosis of piriformis syndrome.

    abstract:INTRODUCTION:Piriformis muscle syndrome (PS) is a disorder encompassing a constellation of symptoms, including buttock and hip pain. In this study we aimed to assess the value of ultrasound (US) in the diagnosis of PS. METHODS:Thirty-three clinically diagnosed PS patients and 26 healthy volunteers underwent a clinical...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26418

    authors: Zhang W,Luo F,Sun H,Ding H

    更新日期:2019-04-01 00:00:00

  • Morvan's syndrome: clinical, laboratory, and in vitro electrophysiological studies.

    abstract::Morvan's syndrome is a rare disorder characterized by neuromyotonia, hyperhidrosis, and central nervous system dysfunction. We report a patient with features of this syndrome, but who initially presented with breathing difficulties. Concentric needle electromyography showed an abundance of myokymic and neuromyotonic d...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20081

    authors: Löscher WN,Wanschitz J,Reiners K,Quasthoff S

    更新日期:2004-08-01 00:00:00

  • Carnitine stimulation of pyruvate dehydrogenase complex (PDHC) in isolated human skeletal muscle mitochondria.

    abstract::L-carnitine stimulated CO2 production from 1-14C pyruvate in mitochondria from human skeletal muscle nearly twofold. A comparable increase in the pyruvate dehydrogenase complex (PDHC) activity was seen. Moreover, in the presence of L-carnitine and at pyruvate concentration greater than 0.25 mM, this effect was associa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110708

    authors: Uziel G,Garavaglia B,Di Donato S

    更新日期:1988-07-01 00:00:00

  • Protein degradation in cultured skeletal muscle from Duchenne muscular dystrophy patients.

    abstract::The loss of contractile protein in Duchenne muscular dystrophy could result from low rates of synthesis, abnormally high rates of protein degradation, or a combination of both. We measured overall protein degradation rates in cultured human muscle cells obtained at biopsy from patients with Duchenne dystrophy or vario...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880080312

    authors: Neville HE,Harrold S

    更新日期:1985-03-01 00:00:00

  • Cytoplasmic body myopathy masquerading as motor neuron disease.

    abstract::Cytoplasmic body myopathy (CBM) is characterized by proteinaceous inclusion bodies in muscle tissue. A 43-year-old woman presented with rapidly progressive weakness and dysphagia. Electromyography (EMG) elsewhere demonstrated lower-limb chronic partial denervation. Muscle biopsy showed fiber size variation without dia...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20115

    authors: Krishnan AV,Pamphlett R,Burke D,Wills EJ,Kiernan MC

    更新日期:2004-11-01 00:00:00

  • Preparation of cell-free extracellular matrix from human peripheral nerve.

    abstract::The extracellular matrix of human peripheral nerve, which is mainly basement membrane and fibrillar collagen, has been prepared by a procedure involving extensive detergent extraction of isolated endoneurium and perineurium obtained from various nerves. The ultrastructure of the isolated nerve extracellular matrix was...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880050410

    authors: Johnson PC,Duhamel RC,Meezan E,Brendel K

    更新日期:1982-04-01 00:00:00

  • Transthyretin amyloidosis presenting with multifocal demyelinating mononeuropathies.

    abstract::We describe a patient with transthyretin amyloidosis who presented with multifocal mononeuropathies with features of demyelination on nerve conduction studies, a constellation of findings not previously described in amyloid polyneuropathy. Genetic testing revealed a valine122isoleucine mutation in the coding region of...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10614

    authors: Briemberg HR,Amato AA

    更新日期:2004-02-01 00:00:00

  • Needlestick injuries among electromyographers.

    abstract::The objective of this study was to determine the self-reported prevalence of needlestick injuries among practicing electromyographers. In January 2008, an anonymous electronic survey was sent to all active members of the American Association for Neuromuscular and Electrodiagnostic Medicine (AANEM) who provided e-mail ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21118

    authors: Mateen FJ,Grant IA,Sorenson EJ

    更新日期:2008-12-01 00:00:00

  • Peripheral nerve atrophy together with higher cerebrospinal fluid progranulin indicate axonal damage in amyotrophic lateral sclerosis.

    abstract:INTRODUCTION:We aimed to investigate whether sonographic peripheral cross-sectional nerve area (CSA) and progranulin (PGRN), a neuritic growth factor, are related to each other and whether they interact to predict clinical and paraclinical measures in amyotrophic lateral sclerosis (ALS). METHODS:We included 55 ALS pat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25682

    authors: Schreiber S,Debska-Vielhaber G,Abdulla S,Machts J,Schreiber F,Kropf S,KÖrtvelyessy P,KÖrner S,Kollewe K,Petri S,Dengler R,Kunz WS,Nestor PJ,Vielhaber S

    更新日期:2018-02-01 00:00:00

  • Neuromuscular complications of connective tissue diseases.

    abstract::The connective tissue diseases, such as rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus, systemic sclerosis, and vasculitis, may cause various disorders of the peripheral nervous system. In this review, the clinical effects of the connective tissues diseases on nerve and muscle are examined with...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/1097-4598(200102)24:2<154::aid-mus20>3.0.c

    authors: Rosenbaum R

    更新日期:2001-02-01 00:00:00

  • Inflammatory processes in amyotrophic lateral sclerosis.

    abstract::Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.10191

    authors: McGeer PL,McGeer EG

    更新日期:2002-10-01 00:00:00

  • Mycophenolate mofetil in the therapy of polymyositis associated with a polyautoimmune syndrome.

    abstract::Mycophenolate mofetil 1.5 g daily (30 mg/kg body weight) was given to a patient with ankylosing spondylitis, ulcerative colitis, and severe refractory polymyositis after conventional treatment regimes had failed. No severe side effects occurred. Considerable improvement of clinical symptoms and electromyographic findi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10026

    authors: Schneider C,Gold R,Schäfers M,Toyka KV

    更新日期:2002-02-01 00:00:00

  • Electrophysiological studies in a mouse model of Schwartz-Jampel syndrome demonstrate muscle fiber hyperactivity of peripheral nerve origin.

    abstract::Schwartz-Jampel syndrome (SJS) is an autosomal-recessive condition characterized by muscle stiffness and chondrodysplasia. It is due to loss-of-function hypomorphic mutations in the HSPG2 gene that encodes for perlecan, a proteoglycan secreted into the basement membrane. The origin of muscle stiffness in SJS is debate...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21253

    authors: Echaniz-Laguna A,Rene F,Marcel C,Bangratz M,Fontaine B,Loeffler JP,Nicole S

    更新日期:2009-07-01 00:00:00

  • Experimental muscle pain does not cause long-lasting increases in resting electromyographic activity.

    abstract::The mutual links between muscle pain and resting electromyographic (EMG) activity are still controversial. This study described effects of experimental muscle pain on resting EMG activity in a jaw-closing muscle and a leg muscle. Pain was induced by injections of hypertonic saline into the muscles in 10 subjects. Inje...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199811)21:11<1382::aid-mus

    authors: Svensson P,Graven-Nielsen T,Matre D,Arendt-Nielsen L

    更新日期:1998-11-01 00:00:00

  • Further observations on forearm flexor weakness in inclusion body myositis.

    abstract::In order to further characterize and provide a possible mechanism for the asymmetrical involvement of forearm muscles in inclusion body myositis (IBM), we measured isometric hand and pinch grip strength, and forearm muscle girth on 15 IBM patients. Forearm muscle strength and girth were significantly greater on the do...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199805)21:5<659::aid-mus17

    authors: Felice KJ,Relva GM,Conway SR

    更新日期:1998-05-01 00:00:00

  • SEPs and CNS magnetic stimulation in syringomyelia.

    abstract::Somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) to transcranial and spinal stimulation from upper and lower limb muscles were elicited in 13 patients with syringomyelia. Seven had an associated Chiari type I anomaly. Diagnosis was confirmed by MRI. In 5 cases, SEPs and MEPs were performed bef...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880150904

    authors: Nogués MA,Pardal AM,Merello M,Miguel MA

    更新日期:1992-09-01 00:00:00

  • Polymyositis--an immunofluorescence study on the distribution of collagen types.

    abstract::Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880030605

    authors: Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

    更新日期:1980-11-01 00:00:00

  • Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study.

    abstract::In spite of extensive studies it is unclear whether impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), i.e., impaired glucose metabolism (IGM), causes diabetic sensorimotor polyneuropathy (DSPN) or chronic idiopathic axonal polyneuropathy (CIAP); the results and conclusions vary considerably in differ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.20846

    authors: Dyck PJ,Dyck PJ,Klein CJ,Weigand SD

    更新日期:2007-10-01 00:00:00