Abstract:
:The efficacy of pentoxifylline (PXF) in vascular inner ear disease (VIED) was studied comparing PXF and placebo in a 4-week study; 60 patients with unilateral loss of hearing, vertigo, dizziness, tinnitus (analyzed with an analogue scale line), and cochlear flow reduction were included. The aim of the study was to study the effect of PXF (1800 mg/day) in VIED considering clinical outcome and cochlear flow. All patients completed the study. Improvement in cochlear flow (p<0.05) and a decrease in score in both groups were observed. The cochlear flow increase was 287.5% in the PXF group vs 168% in the placebo group (119.5% difference; p<0.02). There was a difference in score decrease (44.1% larger) in the PXF group (p<0.05). PXF was more effective considering flow and symptoms.
journal_name
Angiologyjournal_title
Angiologyauthors
Incandela L,Cesarone MR,Belcaro G,De Sanctis MT,Nicolaides AN,Griffin M,Geroulakos G,Ramaswami Gsubject
Has Abstractpub_date
2002-01-01 00:00:00pages
S19-22eissn
0003-3197issn
1940-1574journal_volume
53 Suppl 1pub_type
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