Abstract:
:The cardiorenal anemia syndrome in congestive heart failure (CHF) is an independent risk factor for vascular morbidity and mortality. Several factors play a role in the pathogenesis of anemia in CHF, including inflammation, impaired renal function, use of certain antihypertensive or cardioprotective agents, and gastrointestinal or urinary losses of essential hemopoietic factors. Several trials evaluated the effects of administering erythropoietin (EPO) and/or iron to patients with CHF. Even though most of them were uncontrolled studies, their results suggest that EPO treatment might be beneficial in CHF. Nevertheless, more studies are needed and certain issues should be resolved, particularly the optimal hemoglobin level, before EPO can become part of the treatment of patients with CHF.
journal_name
Angiologyjournal_title
Angiologyauthors
Pagourelias ED,Koumaras C,Kakafika AI,Tziomalos K,Zorou PG,Athyros VG,Karagiannis Adoi
10.1177/0003319708316169subject
Has Abstractpub_date
2009-02-01 00:00:00pages
74-81issue
1eissn
0003-3197issn
1940-1574pii
0003319708316169journal_volume
60pub_type
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