Association of mean platelet volume and pre- and postinterventional flow with infarct-related artery in ST-segment elevation myocardial infarction.

Abstract:

:Platelets play a role in the pathogenesis of ST-segment elevation myocardial infarction (STEMI). We assessed the relationship between mean platelet volume (MPV) on admission and pre- and postinterventional flow with the infarct-related artery (IRA) in patients with STEMI. We prospectively included 840 patients with STEMI who underwent primary percutaneous coronary intervention (PCI). The patients were divided into 3 groups according to MPV tertiles. Pre- and post-PCI Thrombolysis In Myocardial Infarction (TIMI) flow grade was determined. Initial TIMI flow grade 3 was accepted as patent IRA. After the primary PCI, normal flow was defined as post-PCI TIMI flow 3. When the MPV was increased, the incidence of pre-PCI patent IRA (P = .004) and post-PCI normal TIMI flow (P < .001) was significantly decreased. Multivariate analysis showed that MPV was independently associated with post-PCI TIMI flow grade.

journal_name

Angiology

journal_title

Angiology

authors

Elbasan Z,Gür M,Sahin DY,Kuloglu O,Icen YK,Turkoglu C,Ozkan B,Uysal OK,Kalkan GY,Cayli M

doi

10.1177/0003319712455685

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

440-6

issue

6

eissn

0003-3197

issn

1940-1574

pii

0003319712455685

journal_volume

64

pub_type

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