Abstract:
:Platelets play a role in the pathogenesis of ST-segment elevation myocardial infarction (STEMI). We assessed the relationship between mean platelet volume (MPV) on admission and pre- and postinterventional flow with the infarct-related artery (IRA) in patients with STEMI. We prospectively included 840 patients with STEMI who underwent primary percutaneous coronary intervention (PCI). The patients were divided into 3 groups according to MPV tertiles. Pre- and post-PCI Thrombolysis In Myocardial Infarction (TIMI) flow grade was determined. Initial TIMI flow grade 3 was accepted as patent IRA. After the primary PCI, normal flow was defined as post-PCI TIMI flow 3. When the MPV was increased, the incidence of pre-PCI patent IRA (P = .004) and post-PCI normal TIMI flow (P < .001) was significantly decreased. Multivariate analysis showed that MPV was independently associated with post-PCI TIMI flow grade.
journal_name
Angiologyjournal_title
Angiologyauthors
Elbasan Z,Gür M,Sahin DY,Kuloglu O,Icen YK,Turkoglu C,Ozkan B,Uysal OK,Kalkan GY,Cayli Mdoi
10.1177/0003319712455685subject
Has Abstractpub_date
2013-08-01 00:00:00pages
440-6issue
6eissn
0003-3197issn
1940-1574pii
0003319712455685journal_volume
64pub_type
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