Serum γ-glutamyltransferase activity in patients with nonvalvular atrial fibrillation.

Abstract:

:Procoagulant and prothrombotic states in patients with chronic atrial fibrillation (AF) are higher than those in patients with normal sinus rhythm. We assessed and compared serum γ-glutamyltranferase (GGT) activity in elderly patients with nonvalvular AF and control participants with normal sinus rhythm. Consecutive patients (n = 81) with nonvalvular chronic AF and 210 age- and gender-matched control participants with normal sinus rhythm were retrospectively included in the study from the outpatient cardiology clinic. Presence of coronary artery disease, hypertension, gender, hyperlipidemia, diabetes mellitus, smoking status, glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and ejection fraction were comparable between the 2 groups (P > .05 for all). However, serum γ-GGT activity was significantly higher (P = .003) in patients with AF compared with those without AF. We have shown that serum γ-GGT activity is independently associated with chronic nonvalvular AF.

journal_name

Angiology

journal_title

Angiology

authors

Tekin G,Tekin YK,Senarslan DA,Gocmen AY,Senarslan O,Erbay AR

doi

10.1177/0003319712438956

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

157-60

issue

2

eissn

0003-3197

issn

1940-1574

pii

0003319712438956

journal_volume

64

pub_type

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