Impact of Diabetes Mellitus on Critical Limb Ischemia With Below the Knee Disease: Japan Below-the-Knee Artery Treatment Subanalysis.

Abstract:

BACKGROUND:A strong association exists between diabetes mellitus and critical limb ischemia. METHODS AND RESULTS:We performed endovascular therapy on 1060 limbs in 884 patients with below knee lesions only. The patients were divided into diabetes (DG) and nondiabetes groups (NDG). Limb salvage was poorer in the DG (79% vs 89%, P = .0061). No significant difference was observed in mortality, amputation-free survival (AFS), and target vessel revascularization (TVR). Multivariate analysis revealed diabetes status, infection, poor activity of daily living (ADL), younger age, and procedure failure as independent predictors of major amputation in DG. In the NDG, procedure failure was the predictor, and younger age and poor ADL showed tendency of major amputation. CONCLUSIONS:Mortality, AFS, and TVR showed no significant difference between the 2 groups, but major amputation was more frequent in DG. Not only revascularization but also infection and diabetes control were very important for limb salvage in DG.

journal_name

Angiology

journal_title

Angiology

authors

Suzuki K,Iida O,Yamauchi Y,Nakano M,Soga Y,Kawasaki D,Tazaki J,Yamaoka T,Suematsu N,Shintani Y,Miyashita Y,Inoue N,Meguro T

doi

10.1177/0003319713499606

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

444-451

issue

5

eissn

0003-3197

issn

1940-1574

pii

0003319713499606

journal_volume

71

pub_type

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