Abstract:
BACKGROUND:A strong association exists between diabetes mellitus and critical limb ischemia. METHODS AND RESULTS:We performed endovascular therapy on 1060 limbs in 884 patients with below knee lesions only. The patients were divided into diabetes (DG) and nondiabetes groups (NDG). Limb salvage was poorer in the DG (79% vs 89%, P = .0061). No significant difference was observed in mortality, amputation-free survival (AFS), and target vessel revascularization (TVR). Multivariate analysis revealed diabetes status, infection, poor activity of daily living (ADL), younger age, and procedure failure as independent predictors of major amputation in DG. In the NDG, procedure failure was the predictor, and younger age and poor ADL showed tendency of major amputation. CONCLUSIONS:Mortality, AFS, and TVR showed no significant difference between the 2 groups, but major amputation was more frequent in DG. Not only revascularization but also infection and diabetes control were very important for limb salvage in DG.
journal_name
Angiologyjournal_title
Angiologyauthors
Suzuki K,Iida O,Yamauchi Y,Nakano M,Soga Y,Kawasaki D,Tazaki J,Yamaoka T,Suematsu N,Shintani Y,Miyashita Y,Inoue N,Meguro Tdoi
10.1177/0003319713499606subject
Has Abstractpub_date
2020-05-01 00:00:00pages
444-451issue
5eissn
0003-3197issn
1940-1574pii
0003319713499606journal_volume
71pub_type
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