Hemostatic abnormalities in Sneddon's syndrome.

Abstract:

:Sneddon's syndrome is a rare condition comprising widespread livedo retucularis and multiple episodes of transient cerebral ischemia. Treatment to date has been empirical. The hemostatic/thrombotic status of 4 patients with Sneddon's syndrome was studied by a unique technique, hemostatometry, which measures primary hemostasis (shear-induced platelet plug formation), the overall coagulation, and thrombolysis (dislodgment of the hemostatic plugs) from nonanticoagulated blood. In all 4 patients, platelet reactivity, which shows itself in the initial phase of the hemostatic reaction, was enhanced. The overall hemostasis, in which the generation of thrombin by activated platelets plays the decisive role, was enhanced in 3 patients. Three of the 4 patients had hypercoagulation, and in 3, spontaneous thrombolysis was inhibited. Treatment was commenced with aspirin and nifedipine, and patients were monitored both clinically and by serial hemostatometry over two years. One patient had one further transient ischemic episode; the other 3 remained asymptomatic. Thus, the observed clinical improvement correlated with improvement of the hemostatic profile.

journal_name

Angiology

journal_title

Angiology

authors

Mayou SC,Kovacs IB,Ridler CD,Kirby JD

doi

10.1177/000331979204300409

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

342-9

issue

4

eissn

0003-3197

issn

1940-1574

journal_volume

43

pub_type

杂志文章
  • Left ventricular Doppler characteristics in first-degree relatives of patients with hypertrophic cardiomyopathy.

    abstract::Left ventricular (LV) diastolic function may be affected early in patients with hypertrophic cardiomyopathy (HCM), regardless of the phenotypic expression of the disease. The aim of the present study was to detect whether LV diastolic performance, evaluated by conventional Doppler echocardiography, is impaired in firs...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970505600312

    authors: Efthimiadis GK,Parharidis GE,Karvounis HI,Papadopoulos CE,Gemitzis KD,Styliadis IH,Karoulas TN,Louridas GE

    更新日期:2005-05-01 00:00:00

  • Lymphangiomyomatosis--newer concepts in pathogenesis and management--case reports.

    abstract::Lymphangiomyomatosis was first reported more than forty years ago. Although its incidence is rare, its occurrence is being increasingly recognized and has been the subject of a growing number of cases reports in recent years. This study adds 2 more cases to the file. Both cases involved young women with the characteri...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004101110

    authors: Naegeli CD,Cordasco EM,Meden G,O'Donnell JK,MacIntyre WJ,Dishner W

    更新日期:1990-11-01 00:00:00

  • Aortic Distensibility Can Predict Events in Patients With Premature Coronary Artery Disease: A Cardiac Magnetic Resonance Study.

    abstract::Noninvasive assessment of aortic distensibility (AD) is feasible with cardiac magnetic resonance (CMR). We investigated the relationship between AD (assessed by CMR) and coronary artery disease (CAD) severity (assessed by the SYNTAX score) in patients with premature CAD. We recruited 125 patients with CAD confirmed by...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319720968391

    authors: Razik NA,Kishk YT,Essa M,Ghany MA

    更新日期:2020-11-15 00:00:00

  • Serum uric acid concentration and asymptomatic hyperuricemia with subclinical organ damage in general population.

    abstract::We assessed the effect of increased serum uric acid (SUA) concentration and hyperuricemia on subclinical organ damage. A cross-sectional examination of 1243 asymptomatic patients aged 55 to 84 years was conducted from September to October 2012. All participants underwent the measurements of SUA and other established c...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319713513143

    authors: Li Y,Lu J,Wu X,Yang C

    更新日期:2014-08-01 00:00:00

  • Association of mean platelet volume and pre- and postinterventional flow with infarct-related artery in ST-segment elevation myocardial infarction.

    abstract::Platelets play a role in the pathogenesis of ST-segment elevation myocardial infarction (STEMI). We assessed the relationship between mean platelet volume (MPV) on admission and pre- and postinterventional flow with the infarct-related artery (IRA) in patients with STEMI. We prospectively included 840 patients with ST...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319712455685

    authors: Elbasan Z,Gür M,Sahin DY,Kuloglu O,Icen YK,Turkoglu C,Ozkan B,Uysal OK,Kalkan GY,Cayli M

    更新日期:2013-08-01 00:00:00

  • Finger systolic pressures and skin temperatures in severe Raynaud's syndrome: the relationship to healing of skin lesions and the use of oral phenoxybenzamine.

    abstract::Systolic pressures and skin temperatures were studied in 23 patients with severe Raynaud's syndrome who were given oral phenoxybenzamine. There was a relationship between the measurements and the severity of the disease. Statistically significant correlation was found between the measurements and the time for healing ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978103200502

    authors: Carter SA

    更新日期:1981-05-01 00:00:00

  • Impact of Statin Therapy on Plasma MMP-3, MMP-9, and TIMP-1 Concentrations: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.

    abstract::Tissue inhibitors of metalloproteinases (TIMPs) and matrix metalloproteinases (MMPs) are associated with the development of atherosclerosis and cardiovascular disease. Statin therapy has been shown to modulate MMPs and TIMP-1 levels, but clinical findings have not been conclusive. This study aimed to systematically re...

    journal_title:Angiology

    pub_type: 杂志文章,meta分析

    doi:10.1177/0003319716688301

    authors: Ferretti G,Bacchetti T,Banach M,Simental-Mendía LE,Sahebkar A

    更新日期:2017-11-01 00:00:00

  • Sulodexide versus calcium heparin in the medium-term treatment of deep vein thrombosis of the lower limbs.

    abstract::Thirty adult patients with distal, monolateral deep vein thrombosis of the lower limbs were randomly treated for sixty days either with subcutaneous Ca-Heparin or with Sulodexide, administered IM for ten days and orally for fifty days. The thrombus accretion above the knee, the venous pressures of the affected leg, th...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000331979704800907

    authors: Pinto A,Corrao S,Galati D,Arnone S,Licata A,Parrinello G,Maniscalchi T,Licata G

    更新日期:1997-09-01 00:00:00

  • Severe spontaneous carotid artery dissection and multiple aneurysmal dilatations. A case report.

    abstract::Spontaneous cervical artery dissections or arterial aneurysms associated with deficiencies of alpha(1)-antitrypsin (alpha(1)-AT) or other inhibitors of proteolytic enzymes have occasionally been reported. However, a coexistence of severe spontaneous internal carotid artery dissection and multiple aneurysmal dilatation...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979604700912

    authors: Plaschke M,Auer D,Trapp T,Trenkwalder P,Trenkwalder C

    更新日期:1996-09-01 00:00:00

  • In situ endothelin in coronary artery disease.

    abstract::Despite the significant advances made in the understanding and treatment of coronary artery disease much remains unclear about the pathogenesis of this complex atherothrombotic process. Atherogenesis may reflect a combination of multiple factors interacting with one another leading to coronary artery occlusion. One po...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979604701101

    authors: Brody JI,Capuzzi DM,Fink GB

    更新日期:1996-11-01 00:00:00

  • Pentoxifylline for intermittent claudication. A critical review.

    abstract::Pentoxifylline was first introduced in Germany twenty years ago. Today it is the best researched oral drug for intermittent claudication. A total of seventeen placebo-controlled trials could be retrieved from the world literature. The majority of these studies show that pentoxifylline will prolong the walking distance...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331979404500502

    authors: Ernst E

    更新日期:1994-05-01 00:00:00

  • Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study.

    abstract::The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 ...

    journal_title:Angiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0003319716642140

    authors: Tyrovolas S,Polychronopoulos E,Mariolis A,Piscopo S,Valacchi G,Makri K,Zeimbekis A,Tyrovola D,Bountziouka V,Gotsis E,Metallinos G,Tur JA,Matalas A,Lionis C,Haro JM,Panagiotakos DB

    更新日期:2017-02-01 00:00:00

  • Physical activity and cardiovascular disease prevention: current recommendations.

    abstract::Epidemiologic studies support an inverse and robust relationship between physical activity (PA) and mortality risk, even after adjusting for potential confounding factors. The authors have reported 13% lower mortality risk for every 1-MET (metabolic equivalent) increase in exercise capacity. For those with an exercise...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/0003319708318582

    authors: Kokkinos P

    更新日期:2008-04-01 00:00:00

  • Myocardial ultrastructure in Kearns-Sayre syndrome.

    abstract::Myocardial ultrastructural changes are described in a twenty-five-year-old female with typical Kearns-Sayre syndrome. The electrocardiogram revealed complete atrioventricular block with an occasional torsades de pointes type of ventricular tachycardia. His bundle recording demonstrated HV block with normal AH interval...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978703800104

    authors: Nakano T,Imanaka K,Uchida H,Isaka N,Takezawa H

    更新日期:1987-01-01 00:00:00

  • Mortality and morbidity in patients with intermittent claudication in relation to the location of the occlusive atherosclerosis in the leg.

    abstract::Mortality and morbidity from cerebrovascular and coronary arterial disease over a period of six years were studied in 224 non-diabetic patients with intermittent claudication. Patients with multiple arterial stenoses in the leg had a lower six-year survival than patients with single stenoses (55% versus 77%), with a h...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978503600508

    authors: Jonason T,Ringqvist I

    更新日期:1985-05-01 00:00:00

  • Validity of continuous-wave Doppler sonography of the vertebrobasilar system.

    abstract::To assess the value of continuous-wave Doppler sonography for detection and exclusion of lesions in the vertebrobasilar system, the ultrasonic and angiographic findings were compared in a prospective study. Altogether, 200 vertebral arteries in 176 patients were evaluated by both methods. Insonation of the vertebral a...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978703800709

    authors: Karnik R,Stöllberger C,Ammerer HP,Perneczky G,Slany J,Brenner H

    更新日期:1987-07-01 00:00:00

  • Recurrent thrombosis in patients with deep vein thrombosis and/or venous thromboembolism associated with anticardiolipin antibodies.

    abstract::Anticardiolipin antibodies represent one of the main hypercoagulation states associated with venous thromboembolism. The aim of this work was to evaluate symptomatic recurrent thrombosis in patients with anticardiolipin antibodies and deep vein thrombosis of the lower limbs with or without thromboembolism. Sixty patie...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970605700111

    authors: de Godoy JM,de Godoy MF,Braile DM

    更新日期:2006-01-01 00:00:00

  • QT dispersion in single coronary artery disease: is there a relation between QT dispersion and diseased coronary artery or lesion localization?

    abstract::It has been shown that QT dispersion (QTD) increases during episodes of myocardial ischemia or infarction. However, no extensive data on the relation between the diseased coronary artery or the localization of stenosis and the QTD are available. The aim of the study was to examine the relation between QTD and diseased...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970105200106

    authors: Tikiz H,Terzi T,Balbay Y,Demir AD,Soylu M,Keles T,Kutuk E

    更新日期:2001-01-01 00:00:00

  • Changes in blood pressure reactivity and 24-hour blood pressure profile occurring at puberty.

    abstract::To evaluate blood pressure reactivity in children and its changes in adolescents, the acute pressor response to a video-game stress test and the noninvasive ambulatory blood pressure monitoring were evaluated in 62 healthy children divided into three age groups. Basal blood pressure values were measured according to t...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979404500605

    authors: Modesti PA,Pela I,Cecioni I,Gensini GF,Serneri GG,Bartolozzi G

    更新日期:1994-06-01 00:00:00

  • Early exercise test in acute myocardial infarction treated with intravenous streptokinase.

    abstract::The aim of this study was to assess the value of the early exercise test (ET) in patients with acute myocardial infarction (AMI) treated with IV streptokinase (SK). The authors studied 70 patients with first AMI; 31 were treated with SK and 39 were not. Before discharge everyone was given early exercise up to 5-6 METs...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979104200903

    authors: Hamouratidis N,Katsaliakis N,Manoudis F,Lazaridis K,Tselegaridis T,Stravelas V,Simeonidou E,Roussis S

    更新日期:1991-09-01 00:00:00

  • Calf blood flow and systolic blood pressure in patients with hyperviscosity of the blood.

    abstract::The calf blood flow and the ankle blood pressure at rest and during post-ischemic reactive hyperemia were measured by an airfilled rubber segment plethysmograph in 5 patients with hyperviscosity of the blood. The patients had no signs of peripheral arterial disease. A normal flow and pressure pattern was obtained. It ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977903000504

    authors: Valnes K,Lorentsen E,Holter B

    更新日期:1979-05-01 00:00:00

  • Facing Morbid Obesity: How to Approach It.

    abstract::Obesity is a major public health problem, with a prevalence of 10% to 20% in Western Europe. Morbid obesity, characterized by body mass index >40 kg/m(2), showed an increased prevalence in the last 30 years. Obesity is associated with reduced economic and social opportunities, reduced quality of life, and is a determi...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/0003319715595735

    authors: Ricci MA,De Vuono S,Scavizzi M,Gentili A,Lupattelli G

    更新日期:2016-04-01 00:00:00

  • Atherosclerosic dissection of the cervical internal carotid artery--a case report.

    abstract::Atherosclerosis as a cause of spontaneous dissection in the cervical internal carotid arteries has been described in only a few cases. The authors present a surgically and pathologically proven case of dissection on the base of atherosclerosis of the cervical internal carotid artery. A resection of the pathologic segm...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004100212

    authors: De Baets P,Delanote G,Jackers G,De Puydt P,Wilms G

    更新日期:1990-02-01 00:00:00

  • Pulse Wave Velocity in Kawasaki Disease.

    abstract::Kawasaki disease (KD) is an acute childhood febrile disease of unknown etiology. It exhibits not only coronary artery aneurysms in some cases but also systemic vasculitis. Whether KD is associated with accelerated atherosclerosis remains debatable. The measurement of pulse wave velocity (PWV) is useful as a simple, no...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319716651789

    authors: Iwazu Y,Minami T,Kotani K

    更新日期:2017-03-01 00:00:00

  • The effect of short-term treatment with simvastatin on renal function in patients with peripheral arterial disease.

    abstract::The objective of this study was to investigate the effects of lipid-lowering treatment on renal function in patients with peripheral arterial disease (PAD). This was a retrospective study of hyperlipidemic claudicants referred to a vascular surgery and risk modification clinic. Serum creatinine and urate concentration...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970405500108

    authors: Youssef F,Gupta P,Seifalian AM,Myint F,Mikhailidis DP,Hamilton G

    更新日期:2004-01-01 00:00:00

  • Treatment of Raynaud's syndrome with adrenergic alpha-blockade with or without beta-blockade.

    abstract::In a double blind placebo-controlled cross-over trial of 24 weeks 31 patients with Raynaud's syndrome were treated with the alpha-blocker phenoxybenzamine (10-20 mg daily) and with the combination of the alpha-blocker phenoxybenzamine (10-20 mg daily) and the beta-blocker sotalol (40-80 mg daily). A favourable effect ...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章

    doi:10.1177/000331978403500104

    authors: Cleophas TJ,van Lier HJ,Fennis JF,van 't Laar A

    更新日期:1984-01-01 00:00:00

  • Outcomes and risk prediction model for peripheral arterial disease in patients with stable coronary artery disease.

    abstract::We used the National Heart, Lung, and Blood Institute Limited Access Dataset of Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) Trial (n = 8290) which included patients with stable coronary artery disease (CAD) and preserved ejection fraction (>40%). We identified risk factors for the develo...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319711398650

    authors: Badheka AO,Rathod AD,Bharadwaj AS,Bhat S,Kizilbash MA,Veeranna V,Pidlaon V,Jacob S,Afonso L

    更新日期:2011-08-01 00:00:00

  • Effect of long-term administration of buflomedil on regional cerebral blood flow in chronic cerebral infarction.

    abstract::The influence of long-term oral administration of buflomedil on regional cerebral blood flow was investigated in 10 patients with chronic cerebral infarction and mild to moderate mental deterioration. Patients were given 150 mg buflomedil three times daily for a period of eight weeks. Regional cerebral blood flow (rCB...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978803901102

    authors: Kobayashi S,Yamaguchi S,Okada K,Kitani M,Yamashita K,Shimote K,Tsunematsu T

    更新日期:1988-11-01 00:00:00

  • Relationship between plaque morphology of carotid artery and aortic valve calcification.

    abstract::Aortic and mitral valvular calcifications are found to be associated with atherosclerotic risk factors and are largely accepted as part of a generalized atherosclerotic process. As well as the severity of stenosis, embologenic properties of plaques are also responsible for ischemic potentials of atherosclerotic plaque...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970305400601

    authors: Soylu M,Demir AD,Ozdemir O,Uzun Y,Korkmaz S

    更新日期:2003-11-01 00:00:00

  • Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Resear

    abstract::The combination of calcium channel blockers and beta blockers is more effective for the treatment of exercise-induced angina pectoris than beta blocker monotherapy. Since ischemia in exercise-induced angina is essentially preceded by an increase in heart rate, calcium channel blockers with negative chronotropic proper...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1177/000331979905000602

    authors: van der Vring JA,Daniëls MC,Holwerda NJ,Withagen PJ,Schelling A,Cleophas TJ,Hendriks MG

    更新日期:1999-06-01 00:00:00