Abstract:
:Pentoxifylline was first introduced in Germany twenty years ago. Today it is the best researched oral drug for intermittent claudication. A total of seventeen placebo-controlled trials could be retrieved from the world literature. The majority of these studies show that pentoxifylline will prolong the walking distance in a statistically significant way. Even though these trials are conducted with considerable scientific rigor, important flaws can be identified. Whether the symptomatic improvement is clinically relevant is difficult to say and may depend on the patient's individual situation. These collective data show that pentoxifylline prolongs the walking distance in patients with intermittent claudication.
journal_name
Angiologyjournal_title
Angiologyauthors
Ernst Edoi
10.1177/000331979404500502subject
Has Abstractpub_date
1994-05-01 00:00:00pages
339-45issue
5eissn
0003-3197issn
1940-1574journal_volume
45pub_type
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