Abstract:
:Myocardial ultrastructural changes are described in a twenty-five-year-old female with typical Kearns-Sayre syndrome. The electrocardiogram revealed complete atrioventricular block with an occasional torsades de pointes type of ventricular tachycardia. His bundle recording demonstrated HV block with normal AH interval. An endomyocardial biopsy showed "ragged-red fibers" by the modified Gomori trichrome stain, and on electron microscopy there were increased numbers of morphologically abnormal mitochondria: ie, gian mitochondria, a whorled pattern of the cristae, and electron-dense substances, and paracrystalline inclusions in the mitochondria. The patient has been well since pacemaker implantation, but she may develop a clinically overt cardiomyopathy due to progression of myocardial involvement.
journal_name
Angiologyjournal_title
Angiologyauthors
Nakano T,Imanaka K,Uchida H,Isaka N,Takezawa Hdoi
10.1177/000331978703800104subject
Has Abstractpub_date
1987-01-01 00:00:00pages
28-35issue
1 Pt 1eissn
0003-3197issn
1940-1574journal_volume
38pub_type
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