Abstract:
:Ten patients with peripheral obstructive arterial disease (POAD) in stages I and II according to Leriche-Fontaine, were subjected to therapy with mesoglycan sulfate (60 mg/day for twenty days), to evaluate the effect of the drug on the elastic module of the arterial wall. The wall elasticity was deduced from some Doppler velocitographic indices (arterial dynamics index, resistance index, perfusion pressure index, tibial distensibility index); from the analysis of systolic, protodiastolic, and end diastolic velocity variations; and from computerized analysis of the Doppler sound spectrum. The results show a significant improvement of arterial wall elasticity, which suggests a rational use for the drug in the initial stages of peripheral obstructive arterial disease.
journal_name
Angiologyjournal_title
Angiologyauthors
Andreozzi GM,Signorelli S,Lo Duca S,Minacapelli C,Amico-Roxas MT,Minardo G,Cacciaguerra Gdoi
10.1177/000331978703800803subject
Has Abstractpub_date
1987-08-01 00:00:00pages
593-600issue
8eissn
0003-3197issn
1940-1574journal_volume
38pub_type
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