Vascular Reactivity is Impaired and Associated With Walking Ability in Patients With Intermittent Claudication.

Abstract:

:We verified whether vascular reactivity is impaired and whether there is any association between vascular reactivity, walking ability, and peripheral artery disease (PAD) severity in patients with intermittent claudication (IC). We studied 63 patients and 17 age- and sex-matched volunteers without PAD. Vascular reactivity was evaluated in the brachial artery during reactive hyperemia (flow-mediated dilation [FMD]) and after a sublingual single dose of nitroglycerin (nitroglycerin-induced vasodilation [NID]). Walking ability was verified by a 6-minute walk test. Vascular reactivity and walking ability were significantly worse in patients with IC compared with control participants. The ankle-brachial index correlated with FMD, NID, as well as total and pain-free distances. The NID and walking ability progressively decreased as PAD severity increased. Walking ability correlated with NID but not with FMD. In patients with IC, vascular reactivity is impaired and is related to the severity of PAD and to walking ability.

journal_name

Angiology

journal_title

Angiology

authors

Silva Rde C,Wolosker N,Yugar-Toledo JC,Consolim-Colombo FM

doi

10.1177/0003319714545486

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

680-6

issue

7

eissn

0003-3197

issn

1940-1574

pii

0003319714545486

journal_volume

66

pub_type

杂志文章
  • Beta-blocker-induced psoriasis: a rare side effect--a case report.

    abstract::Beta blockers are one of the oral agents shown to decrease cardiovascular morbidity and mortality rates in randomized, controlled trials, and hence, they are widely used for the management of many cardiovascular situations. In terms of side effects there are 3 major modes of action: (1) contraction of smooth muscles, ...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331970205300617

    authors: Yilmaz MB,Turhan H,Akin Y,Kisacik HL,Korkmaz S

    更新日期:2002-11-01 00:00:00

  • Bilateral fistulas from the internal mammary arteries and the bronchial arteries to the pulmonary arteries--a case report.

    abstract::A 78-year-old man was admitted to hospital with heart failure and chronic bronchitis. A computed tomographic scan of the chest incidentally demonstrated bilateral abnormal vessels near the left atrium. Selective angiography showed that both internal mammary arteries and bronchial arteries communicated with the pulmona...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979804901010

    authors: Misumi I,Ueno K,Kimura Y,Hokamura Y,Yamabe H,Yasunaga T,Oguni T,Asao C

    更新日期:1998-09-01 00:00:00

  • Atherosclerosis vascular damage in elderly athletes and sedentary people.

    abstract::The objective of this study was to determine the degree of vascular atherosclerotic damage at the carotid and femoral levels in a group of subjects over sixty years old practicing endurance sports. Using high-resolution Doppler-color flow ultrasonography the authors carried out a vascular screening, comparing two dist...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704800709

    authors: Galetta F,Rossi M,Franzoni F,Credidio L,Vagheggini G

    更新日期:1997-07-01 00:00:00

  • Therapy for late post infarction ventricular tachycardia.

    abstract::Non-sustained ventricular tachycardia (VT) in the late post myocardial infarction (MI) period (7-21 days) has been reported to be a predictor of sudden death. We suspected that patients with 3 beat VT on Holter monitoring in the late infarction period would demonstrate electrical instability at electrophysiologic stud...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章

    doi:10.1177/000331978503600307

    authors: Somberg JC,Butler B,Torres V,Tepper D,Keren G,Siegel L,Jentzer J,Miura DS

    更新日期:1985-03-01 00:00:00

  • Liver Function is Associated With Response to Clopidogrel Therapy in Patients Undergoing Angioplasty and Stenting.

    abstract::The relationship between liver function and clopidogrel response has not been studied so far. We therefore sought to investigate the associations between 3 parameters of liver synthesis and on-treatment platelet reactivity to adenosine diphosphate in patients on dual antiplatelet therapy. On-treatment platelet reactiv...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319715609011

    authors: Gremmel T,Mueller M,Koppensteiner R,Panzer S

    更新日期:2016-10-01 00:00:00

  • Successful transcatheter closure of a patent ductus arteriosus: using two Gianturco coils in a 41-year-old woman. A case report.

    abstract::Patent ductus arteriosus (PDA) is a form of congenital heart disease uncommonly diagnosed in adult patients. Transcatheter closure of PDA has been widely used in children. However, the experience is limited in adults especially with use of Gianturco coils. The authors describe a case of successful transcatheter closur...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331979905000612

    authors: Shamsham F,Kwan T,Safi AM,Clark LT

    更新日期:1999-06-01 00:00:00

  • Emergency coronary stenting for complete thrombotic occlusion of an unprotected left main coronary artery in acute myocardial infarction complicated by cardiogenic shock in an octogenarian patient--a case report.

    abstract::This report concerns an 82-year-old white man, who was admitted with cardiogenic shock secondary to an acute anterior myocardial infarction with right bundle branch block requiring an intra-aortic balloon pump for hemodynamic support and mechanical ventilatory support for respiratory distress. An immediate cardiac cat...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970205300113

    authors: Tariq M,Carroll R,Zabih I,Stenberg RG,Hussain KM

    更新日期:2002-01-01 00:00:00

  • Outcomes and risk prediction model for peripheral arterial disease in patients with stable coronary artery disease.

    abstract::We used the National Heart, Lung, and Blood Institute Limited Access Dataset of Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) Trial (n = 8290) which included patients with stable coronary artery disease (CAD) and preserved ejection fraction (>40%). We identified risk factors for the develo...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319711398650

    authors: Badheka AO,Rathod AD,Bharadwaj AS,Bhat S,Kizilbash MA,Veeranna V,Pidlaon V,Jacob S,Afonso L

    更新日期:2011-08-01 00:00:00

  • Early exercise test in acute myocardial infarction treated with intravenous streptokinase.

    abstract::The aim of this study was to assess the value of the early exercise test (ET) in patients with acute myocardial infarction (AMI) treated with IV streptokinase (SK). The authors studied 70 patients with first AMI; 31 were treated with SK and 39 were not. Before discharge everyone was given early exercise up to 5-6 METs...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979104200903

    authors: Hamouratidis N,Katsaliakis N,Manoudis F,Lazaridis K,Tselegaridis T,Stravelas V,Simeonidou E,Roussis S

    更新日期:1991-09-01 00:00:00

  • Clinical evaluation of coronary lesion characteristics in acute myocardial infarction.

    abstract::Coronary lesion instability at the onset of acute myocardial infarction (AMI) was evaluated. The mechanism of AMI has been considered to be coronary lesion instability with occlusive thrombus, although more than one half of AMI occurs in clinically stable patients. A total of 313 AMI patients treated by primary percut...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970305400303

    authors: Tomoda H,Aoki N

    更新日期:2003-05-01 00:00:00

  • Hyperbaric oxygen therapy in chronic vascular wound management.

    abstract::Many nonhealing tissues are hypoxic, with oxygen tensions frequently ranging from 5 to 15 mmHg. In such an environment, the normal wound healing sequence is disrupted or halted and phagocytic killing activity depressed. So the adjunctive use of hyperbaric oxygen (HBO), based on physiologic data and clinical observatio...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004100109

    authors: Wattel F,Mathieu D,Coget JM,Billard V

    更新日期:1990-01-01 00:00:00

  • In situ endothelin in coronary artery disease.

    abstract::Despite the significant advances made in the understanding and treatment of coronary artery disease much remains unclear about the pathogenesis of this complex atherothrombotic process. Atherogenesis may reflect a combination of multiple factors interacting with one another leading to coronary artery occlusion. One po...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979604701101

    authors: Brody JI,Capuzzi DM,Fink GB

    更新日期:1996-11-01 00:00:00

  • Plaque rupture on the carotid artery observed by Doppler ultrasonography--a case report.

    abstract::Plaque rupture may play an important role in acute cerebral events. Recent technological advances in ultrasonographic systems provide a feasible diagnostic modality of atherosclerotic lesion by clearly visualizing flow conditions and vessel morphology. A 58-year-old man with chronic renal failure underwent duplex Dopp...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970105201210

    authors: Ohyama H,Mizushige K,Takahashi T,Hosomi N,Kohno M

    更新日期:2001-12-01 00:00:00

  • Accelerated transplant coronary artery disease and massive silent acute myocardial infarction in a heart transplant patient--a case report and brief review of literature.

    abstract::This case report describes an aggressive form of accelerated atherosclerosis predicted early after transplant by dobutamine stress echocardiography in a patient who died of massive myocardial infarction 32 months after transplantation. The main objective finding of this event was markedly increased cardiac filling pre...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331979905001110

    authors: Rossignol DA,Kipreos B,Akosah K,Mohanty PK

    更新日期:1999-11-01 00:00:00

  • Effect of pentoxifylline on microvascular blood flow velocity.

    abstract::Pentoxifylline (PF), known to increase red blood cell (RBC) deformability, has recently attracted much attention because of its possible effect of reducing capillary resistance. There has been practically no reliable demonstration of an increase in capillary blood flow by this drug. This study was intended to examine ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978103201103

    authors: Ohshima N,Sato M

    更新日期:1981-11-01 00:00:00

  • Silent coronary artery-left ventricular fistula: a disorder of the thebesian system?

    abstract::Two cases with abnormal electrocardiogram were found to have the unusual direct communication between the coronary artery and left ventricular chamber without any manifestations of the other reported coronary arterial fistula. ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977802900211

    authors: Cha SD,Singer E,Maranhao V,Goldberg H

    更新日期:1978-02-01 00:00:00

  • Successful treatment of primary cardiac angiosarcoma with docetaxel and radiotherapy.

    abstract::A 49-year-old man was admitted for primary cardiac angiosarcoma with a cardiac tamponade. Transthoracic echocardiography and contrast-enhanced computed tomography scan demonstrated a large mass in the right atrium and thickening of the right ventricular wall. 18F-labeled deoxyglucose (FDG) positron emission tomography...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319707308212

    authors: Nakamura-Horigome M,Koyama J,Eizawa T,Kasai H,Kumazaki S,Tsutsui H,Koiwai K,Oguchi K,Kinoshita O,Ikeda U

    更新日期:2008-06-01 00:00:00

  • Errors of computer electrocardiography.

    abstract::A review of 6938 computer-generated electrocardiogram interpretations was undertaken by a single cardiologist. The computer-assisted program correctly interpreted 51.6% of the tracings. One or more corrections were necessary in 48.4%. The greatest number of incorrect interpretations involved repolarization (T wave) ab...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704801204

    authors: RuDusky BM

    更新日期:1997-12-01 00:00:00

  • Ranolazine enhances the antiarrhythmic activity of amiodarone by accelerating conversion of new-onset atrial fibrillation after cardiac surgery.

    abstract::Ranolazine is a relatively novel antiischemic/antianginal compound with antiarrhythmic properties. We investigated its ability to shorten the time to conversion of postoperative atrial fibrillation (POAF) when added to amiodarone after coronary artery bypass graft (CABG) surgery. In this prospective, randomized, alloc...

    journal_title:Angiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0003319713477911

    authors: Simopoulos V,Tagarakis GI,Daskalopoulou SS,Daskalopoulos ME,Lenos A,Chryssagis K,Skoularingis I,Molyvdas PA,Tsilimingas NB,Aidonidis I

    更新日期:2014-04-01 00:00:00

  • Microvascular changes in venous disease: an update.

    abstract::In an overview the microvascular involvement in chronic venous insufficiency (CVI) is described. Microangiopathy in the lower leg areas is characterized by the presence of typical enlarged and ramified blood capillaries, reduced capillary number, microvascular thrombosis and obliterations, and/or increased permeabilit...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704800105

    authors: Bollinger A,Leu AJ,Hoffmann U,Franzeck UK

    更新日期:1997-01-01 00:00:00

  • Coronary arteriographic findings during early hours of acute myocardial infarction: response to intracoronary injection of nitrates.

    abstract::We performed coronary arteriography and gave intracoronary injection of nitrates within 8 hours after the onset of symptoms of acute myocardial infarction in eighteen patients. Improved distal filling or patency of the total occluded coronary artery after intracoronary injection of nitrates occurred in 4 of 18 patient...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978303400807

    authors: Omote S,Yasue H,Takizawa A,Nagao M,Hyon H,Nishida S,Horie M

    更新日期:1983-08-01 00:00:00

  • Quality assurance of high-dose i.v. heparin treatment exemplified by patients implanted with coronary Palmaz-Schatz stents.

    abstract::The need to standardize treatment with high-dose IV standard heparin by using activated partial thromboplastin time (APTT) reagents tested for their heparin sensitivity and by establishing a standard treatment schedule led to the development of the "Lainz concept" of heparin management. The determination of heparin se...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979504600404

    authors: Haushofer A,Halbmayer WM,Prachar H,Fischer M

    更新日期:1995-04-01 00:00:00

  • Pattern of angiomas in the Igbos of Nigeria.

    abstract::Almost all angiomas fall into three main groups--hemangioma, lymphangioma, and glomangioma. Fifty-one such angiomas were found in approximately 7500 surgical specimens examined at a central laboratory serving the Igbos of Nigeria. The youngest patient was aged 19 days and the oldest 70 years. Most patients presented i...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977702801110

    authors: Onuigbo WI

    更新日期:1977-11-01 00:00:00

  • The Turkish validity and reliability of the venous insufficiency epidemiological and economic study-quality of life/symptoms scales.

    abstract::The aim of the study was to test Turkish validity and reliability of Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms (VEINES-QoL/Sym) in patients with chronic venous insufficiency (CVI). A total of 118 patients with CVI hospitalized in 3 different hospitals were enrolled in this study....

    journal_title:Angiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0003319710394159

    authors: Kutlu A,Yilmaz E,Ceçen D,Eser E,Ozbakkaloglu A

    更新日期:2011-05-01 00:00:00

  • Success, safety, and efficacy of implantation of diamond-like carbon-coated stents.

    abstract::The aim of this study was to evaluate safety and clinically defined efficacy of the implantation of a new stent coated with diamond-like carbon (DLC stent), in a group of patients who underwent percutaneous transluminal coronary revascularization procedures in two hemodynamic centers. This study was an observational p...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319707300360

    authors: Salahas A,Vrahatis A,Karabinos I,Antonellis I,Ifantis G,Gavaliatsis I,Anthopoulos P,Tavernarakis A

    更新日期:2007-04-01 00:00:00

  • Lymphangiomyomatosis--newer concepts in pathogenesis and management--case reports.

    abstract::Lymphangiomyomatosis was first reported more than forty years ago. Although its incidence is rare, its occurrence is being increasingly recognized and has been the subject of a growing number of cases reports in recent years. This study adds 2 more cases to the file. Both cases involved young women with the characteri...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004101110

    authors: Naegeli CD,Cordasco EM,Meden G,O'Donnell JK,MacIntyre WJ,Dishner W

    更新日期:1990-11-01 00:00:00

  • Lysis block treatment: a new form of local thrombolysis.

    abstract::Lysis block treatment (LBT) is a new form of fibrinolytic therapy for deep vein thrombosis and arterial occlusion in the distal parts of the limbs. Strictly local lysis was achieved by placing a cuff around the thigh or the upper arm, inflating the cuff to a pressure of 500 mmHg ("Bier's blockade"), and giving heparin...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979404500210

    authors: Martin M,Heimig T,Fiebach BJ,Magnus L,Riedel C

    更新日期:1994-02-01 00:00:00

  • Primary Coronary Intervention in Octogenarians and Nonagenarians With ST-Segment Elevation Myocardial Infarction: A Canadian Single-Center Perspective.

    abstract::The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319717746520

    authors: Sharma R,Hiebert B,Cheung D,Jassal DS,Minhas K

    更新日期:2018-09-01 00:00:00

  • The relationship between lower extremity functional strength and severity of peripheral arterial disease.

    abstract::The purposes of this study were to (1) determine if peripheral arterial disease (PAD) severity is related to deficits in lower extremity functional strength, (2) identify covariates that might affect the relationship between lower extremity functional strength and severity of PAD, and (3) determine if the relationship...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970405500401

    authors: Atkins LM,Gardner AW

    更新日期:2004-07-01 00:00:00

  • Cardiac Trauma.

    abstract::Cardiac trauma is a leading cause of death in the United States and occurs mostly due to motor vehicle accidents. Blunt cardiac trauma and penetrating chest injuries are most common, and both can lead to aortic injuries. Timely diagnosis and early management are the key to improve mortality. Cardiac computed tomograph...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/0003319715627954

    authors: Gosavi S,Tyroch AH,Mukherjee D

    更新日期:2016-11-01 00:00:00