Primary Coronary Intervention in Octogenarians and Nonagenarians With ST-Segment Elevation Myocardial Infarction: A Canadian Single-Center Perspective.

Abstract:

:The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary percutaneous coronary intervention (pPCI). Between 2009 and 2015, individuals >80 years of age (very elderly patients) with an STEMI presenting at a single tertiary Canadian care center were included in the study. A random sample of 100 individuals aged 65 to 69 years over the same time period were selected as a control group. A total of 284 patients were included in the study population including 100 controls, 164 octogenarians, and 20 nonagenarians. Of total, 1661 pPCIs occurred during this study period with the very elderly population (>80 years) comprising 11.1% of the total pPCIs. Compared with controls, individuals aged >80 are more likely to have a delay in treatment with increased rates of bleeding, acute kidney injury, rehospitalization, and a trend toward longer hospital stays following pPCI for STEMI. Although in-hospital and 1-year mortality were similar between both cohorts >80 years of age with STEMI, their overall survival was reduced compared with controls.

journal_name

Angiology

journal_title

Angiology

authors

Sharma R,Hiebert B,Cheung D,Jassal DS,Minhas K

doi

10.1177/0003319717746520

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

718-723

issue

8

eissn

0003-3197

issn

1940-1574

journal_volume

69

pub_type

杂志文章
  • A comparison of transradial and transfemoral approaches for percutaneous coronary intervention in elderly patients based on a propensity score analysis.

    abstract::The transradial approach (TRA) has been used as access site for percutaneous coronary intervention (PCI) for years. However, no large sample study has evaluated the effect of TRA in elderly patients. A total of 1098 elderly patients (age ≥ 75 years) who underwent PCI by TRA or transfemoral approach were recruited. A 1...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319714535971

    authors: He PY,Yang YJ,Qiao SB,Xu B,Yao M,Wu YJ,Yuan JQ,Chen J,Liu HB,Dai J,Tang XR,Wang Y,Li W,Gao RL

    更新日期:2015-05-01 00:00:00

  • Oral mycophenolate mofetil prevents in-stent intimal hyperplasia without edge effect.

    abstract::Neointimal hyperplasia is in the forefront in in-stent restenosis. Prevention of in-stent restenosis is possible by reducing and inhibiting the hyperplasia of smooth muscle cells. The authors planned this study to test the hypothesis that when administered orally, mycophenolate mofetil (MMF) could inhibit in-stent neo...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319706293120

    authors: Ilkay E,Tirikli L,Ozercan I,Yavuzkir M,Karaca I,Rahman A,Arslan N

    更新日期:2006-10-01 00:00:00

  • Long-term effect of lipid-lowering therapy on atherosclerosis of abdominal aorta in patients with hypercholesterolemia: noninvasive evaluation by a new image analysis program.

    abstract::Recent clinical studies have demonstrated that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors are effective in the prevention of cardiovascular events and regression of atherosclerotic lesions evaluated by angiography. In this study, the authors investigated how lipid-lowering therapy effects on ...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章

    doi:10.1177/000331970205300108

    authors: Arai Y,Hirose N,Yamamura K,Kimura M,Murayama A,Fujii I,Tsushima M

    更新日期:2002-01-01 00:00:00

  • Serum zinc concentration in acute myocardial infaction.

    abstract::The serum zinc concentration was examined in 61 patients with acute myocardial infarction who were admitted within twenty-four hours after the onset. Forty-two of 61 patients were admitted within twelve hours. The zinc level fell sharply as early as within three hours after the onset. The minimum values were attained ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004100610

    authors: Katayama T,Honda Y,Yamasaki H,Kitamura S,Okano Y

    更新日期:1990-06-01 00:00:00

  • Noninvasive hemodynamic assessment of vasospasm in patients with primary Raynaud's phenomenon.

    abstract::In order to assess vasospastic ischemic disease objectively 41 patients with primary Raynaud's phenomenon and 21 normal volunteers were investigated noninvasively by digital systolic blood pressure and digital skin temperature measurements before and after instant cold provocation. Much care had been taken to be certa...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978703800406

    authors: van de Wal HJ,Wijn PF,van Lier HJ,Kneepkens WG,Skotnicki SH

    更新日期:1987-04-01 00:00:00

  • Relation of arterial properties to left ventricular hypertrophy in hypertensive adults: focus on gender-related differences.

    abstract:BACKGROUND:Although gender-related differences in ventricular remodeling and arterial stiffness have been described, the impact of gender on the association between vascular compliance and left ventricular hypertrophy (LVH) has not been investigated. The current study was designed to determine the gender-related differ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319709355800

    authors: Cernes R,Peer M,Boaz M,Harpaz D,Matas Z,Shargorodsky M

    更新日期:2010-07-01 00:00:00

  • Comparison of Iodixanol and Iopromide in Patients With Renal Insufficiency and Congestive Heart Failure Undergoing Coronary Angiography by Hemodynamic Monitoring.

    abstract::We investigated the impact of contrast media (CM) with different osmolality on cardiac preload in patients with chronic kidney disease (CKD) and congestive heart failure (CHF). Patients with CKD and CHF were equally randomized to receive either iso-osmolar contrast media (IOCM) iodixanol or low-osmolar contrast media ...

    journal_title:Angiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0003319717701868

    authors: Qian G,Yang YQ,Dong W,Cao F,Chen YD

    更新日期:2017-11-01 00:00:00

  • Influence of glucagon on the cardiovascular effects of procainamide.

    abstract::Effects of glucagon on procainamide-induced cardiac toxicity were studied in anesthetized dogs. Procainamide in doses of 50 and 100 mg/kg produced dose-dependent decreases in the blood pressure, cardiac output, left ventricular work index, and left ventricular systolic pressure; and increases in the left ventricular e...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977702800803

    authors: Prasad K,Weckworth P

    更新日期:1977-08-01 00:00:00

  • Double-blind, crossover study of the clinical efficacy and the hemorheological effects of pentoxifylline in patients with occlusive arterial disease of the lower limbs.

    abstract::The effect of a 3 month daily administration of 800 mg pentoxifylline (Trental 400 bds) or placebo was assessed under double blind crossover design in 18 patients (12 males and 6 females) with peripheral occlusive arterial disease in respect of painfree walking distance and various hemorheological and hemostasiologica...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章

    doi:10.1177/000331978403500709

    authors: Strano A,Davi G,Avellone G,Novo S,Pinto A

    更新日期:1984-07-01 00:00:00

  • Microvascular changes in venous disease: an update.

    abstract::In an overview the microvascular involvement in chronic venous insufficiency (CVI) is described. Microangiopathy in the lower leg areas is characterized by the presence of typical enlarged and ramified blood capillaries, reduced capillary number, microvascular thrombosis and obliterations, and/or increased permeabilit...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704800105

    authors: Bollinger A,Leu AJ,Hoffmann U,Franzeck UK

    更新日期:1997-01-01 00:00:00

  • Coronary wallstent implantation by the transradial artery approach. A case report.

    abstract::The authors report the implantation of two wallstents in a patient by use of the transradial artery approach. This approach for coronary wallstent implantation allows for intensive anticoagulation therapy with less risk of bleeding. ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704801008

    authors: Herz I,Assali A,Shor N,Solodky A,Sclarovsky S

    更新日期:1997-10-01 00:00:00

  • Microcirculation after standardized application of Essaven gel on normal skin--a placebo-controlled, randomized study.

    abstract::Essaven gel (EG) is a naturally derived compound indicated for the treatment of impaired venous circulation and, in microcirculatory disorders, hematomas, swelling, sprains, and all minor sport injuries. The aim of this randomized, placebo-controlled, double-blind study was to evaluate the standardized application of ...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/0003319701052003S03

    authors: Incandela L,Belcaro G,Nicolaides AN,Geroulakos G,Cesarone MR,De Sanctis MT

    更新日期:2001-12-01 00:00:00

  • Venous plethysmography applied in pathologic conditions.

    abstract::The correlation between venography and SGP in 41 patients was studied. Fourteen normal subjects were used as a reference. SGP was shown to be very sensitive (97.5%), including proximal and distal DVT, and highly specific (96.4%). After some recommendations for patient positioning and technical use, it will enhance bot...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978103201204

    authors: Baccalon H,Chikhany G,Lozes A,Vaislic C,Puel P,Enjalbert A

    更新日期:1981-12-01 00:00:00

  • Electrocardiographic abnormalities in cerebrovascular accidents.

    abstract::The electrocardiographic abnormalities found in 100 patients with acute cerebrovascular disease and previously normal hearts are described. The abnormalities were more often seen in patients with intracerebral and subarachnoid hemorrhages. The most common changes were Q-Tc Prolongation and ST segment and T wave abnorm...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979004100902

    authors: Ramani A,Shetty U,Kundaje GN

    更新日期:1990-09-01 00:00:00

  • Plaque rupture on the carotid artery observed by Doppler ultrasonography--a case report.

    abstract::Plaque rupture may play an important role in acute cerebral events. Recent technological advances in ultrasonographic systems provide a feasible diagnostic modality of atherosclerotic lesion by clearly visualizing flow conditions and vessel morphology. A 58-year-old man with chronic renal failure underwent duplex Dopp...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970105201210

    authors: Ohyama H,Mizushige K,Takahashi T,Hosomi N,Kohno M

    更新日期:2001-12-01 00:00:00

  • Circumferential spontaneous coronary artery dissection in an elderly man: a case report.

    abstract::An 82-year-old man developed acute inferior myocardial infarction. Emergent coronary angiography demonstrated thrombotic occlusion in the right coronary artery. Intracoronary thrombolytic therapy was performed with successful recanalization. However, circumferential dissection with luminal stenosis was revealed at the...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979804900112

    authors: Koga T,Sakamoto A,Nakamura Y,Kawazoe N,Sadoshima S,Onoyama K,Fujishima M

    更新日期:1998-01-01 00:00:00

  • Mitral valve prolapse: whiplike motion of the posterior mitral leaflet detected by two-dimensional echocardiography.

    abstract::Thirty-four patients with symptoms suggesting mitral valve prolapse were evaluated by M-mode echocardiography, real time, two-dimensional, phase array echocardiography, and cardiac catheterization. Ten of these patients had unequivocal evidence of mitral valve prolapse during cardiac catheterization. This diagnosis wa...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978003100307

    authors: Kounis NG

    更新日期:1980-03-01 00:00:00

  • Effects of intravenous streptokinase and CLS 2210 (calcium dobesilate) on the biochemical markers of early acute myocardial infarction: a historic comparison with both studies.

    abstract::In a previous double-blind, randomized study, CLS 2210 (a new formulation of calcium dobesilate) or placebo was administered by intravenous infusion to 41 patients having their first acute myocardial infarction. In the present study 19 comparable patients were treated intravenously with streptokinase under identical c...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979204300904

    authors: Szlavy L,Repa I,Lengye I,Lamboy L

    更新日期:1992-09-01 00:00:00

  • Anomalous chordae tendinae. A source of echocardiographic confusion.

    abstract::A unique instance of an anomalous chorda tendinae visualized in the left ventricular outflow tract during M-Mode and two-dimensional echocardiography, and subsequently confirmed during surgery for concomitant severe rheumatic valvular disease, is described. The M-Mode appearance can be confused with more serious forms...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978203301108

    authors: Choo MH,Chia BL,Wu DC,Tan AT,Ee BK

    更新日期:1982-11-01 00:00:00

  • Bifascicular block complicating blunt cardiac injury. A case report and review of the literature.

    abstract::A thirty-five-year-old horse trainer presented to the emergency room of the authors' hospital with minimal nonpenetrating chest injury after having been kicked by a horse. No rib or sternum fractures were demonstrated. The admission ECG demonstrated a right bundle branch block and a left anterior hemiblock that were p...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331979404501008

    authors: Pontillo D,Capezzuto A,Achilli A,Serraino L,Savelli S,Guerra R

    更新日期:1994-10-01 00:00:00

  • High 2,3-DPG blood cardioplegia and myocardial preservation during cardiopulmonary bypass.

    abstract::Blood may provide superior cardioplegia compared with crystalloid cardioplegic solution. However, the results are controversial. This may be due to a leftward shift of the hemoglobin (Hb)-O2 dissociation curve induced by hypothermia, increasing the oxygen affinity for Hb. This effect may negate the potential benefit o...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978803900201

    authors: Card RT,Prasad K,Bharadwaj B,Hnatuk LA,MacFadyen MA

    更新日期:1988-02-01 00:00:00

  • Lysis block treatment: a new form of local thrombolysis.

    abstract::Lysis block treatment (LBT) is a new form of fibrinolytic therapy for deep vein thrombosis and arterial occlusion in the distal parts of the limbs. Strictly local lysis was achieved by placing a cuff around the thigh or the upper arm, inflating the cuff to a pressure of 500 mmHg ("Bier's blockade"), and giving heparin...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979404500210

    authors: Martin M,Heimig T,Fiebach BJ,Magnus L,Riedel C

    更新日期:1994-02-01 00:00:00

  • Effect of long-term administration of buflomedil on regional cerebral blood flow in chronic cerebral infarction.

    abstract::The influence of long-term oral administration of buflomedil on regional cerebral blood flow was investigated in 10 patients with chronic cerebral infarction and mild to moderate mental deterioration. Patients were given 150 mg buflomedil three times daily for a period of eight weeks. Regional cerebral blood flow (rCB...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978803901102

    authors: Kobayashi S,Yamaguchi S,Okada K,Kitani M,Yamashita K,Shimote K,Tsunematsu T

    更新日期:1988-11-01 00:00:00

  • The clinical impact of the newer research in blood rheology: an overview.

    abstract::Over the last two decades concepts of hemorheology became established and required methods and techniques developed. Progress was made in the formation of a field of clinical hemorheology. The role of viscosity factors in various disorders has been established, especially in heart disease and diabetes. It has been rec...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978103200401

    authors: Dintenfass L

    更新日期:1981-04-01 00:00:00

  • Reversal of gangrenous lesions in the blue toe syndrome with lovastatin--a case report.

    abstract::A seventy-six-year-old man with ischemic heart disease, peripheral vascular disease, and chronic renal failure developed bilateral cyanotic toes, which upon muscle biopsy, were shown to be caused by atheromatous emboli. The probable source was atheromatosis of the abdominal aorta. The toes became gangrenous, but surgi...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979304401010

    authors: Cabili S,Hochman I,Goor Y

    更新日期:1993-10-01 00:00:00

  • Thromboangiitis obliterans (Buerger's disease) in women (a reevaluation).

    abstract::Thromboangiitis obliterans (TAO) is an occlusive vascular disease traditionally known to be almost exclusive to young male smokers. The disease was considered to be extremely rare in women, seen only as isolated, novel case reports in the literature. In the past decade, however, a dramatic increase in the incidence of...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979304400704

    authors: Yörükoğlu Y,Ilgit E,Zengin M,Nazliel K,Salman E,Yucel E

    更新日期:1993-07-01 00:00:00

  • Effects of verapamil and magnesium sulfate on electrophysiologic changes during acute myocardial ischemia and following reperfusion in dogs: comparative effects of administration by intravenous and coronary sinus retroperfusion routes.

    abstract::The authors evaluated the effects of verapamil (Ve) and magnesium sulfate (Mg) on the electrophysiologic changes induced in dogs during acute myocardial ischemia and following reperfusion. The effects of their intravenous (i.v.) administration and administration by coronary sinus retroperfusion (CSR) were also compare...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979604700604

    authors: Yamamoto K,Bando S

    更新日期:1996-06-01 00:00:00

  • Patient assessment and examples of a method of treatment. Use of the circulator boot in peripheral vascular disease.

    abstract::Effective peripheral blood flow is positively related to cardiac output and gravity (part dependent) and inversely related to gravity (part elevated), venous pressure, interstitial fluid pressure, degree of peripheral neuropathy, arteriosclerotic and thrombotic arterial obstructions, and infection. These factors are c...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319797048005S04

    authors: Dillon RS

    更新日期:1997-05-01 00:00:00

  • Systolic time intervals and heart sounds in left bundle branch block.

    abstract::Systolic time intervals and heart sounds were studied in twenty patients with left bundle branch block. A definite cause for the organic heart disease was not ascertained. Abnormal duration of the electromechanical systole (Q-A2), due to a prolongation both of the preejection period (PEP) and of the Q-M1 intervals, wa...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977602700705

    authors: Macieira-Coelho E,Lema-Santos A,Machado HB,Faleiro LL

    更新日期:1976-07-01 00:00:00

  • Quantitative assessment of peripheral arterial obstruction in Raynaud's phenomenon: development of a predictive model of obstructive arterial cross-sectional area and validation with a Doppler blood flow study.

    abstract::The objective of this study was to develop a method for the analytical assessment of arterial obstruction in conditions of Raynaud's phenomenon capable of providing diagnostic criteria. Numerous attempts have been made to determine and quantify arterial obstruction in terms of Doppler ultrasound measurements of arteri...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970005101202

    authors: Seitz WS,Kline HJ,McIlroy MB

    更新日期:2000-12-01 00:00:00