A study on left atrial transport function. Effect of age or left ventricular ejection fraction on left atrial storage fraction.

Abstract:

:Left atrial (LA) storage fraction is defined as the ratio of storage volume of the left atrium (LA) during ventricular systole to left ventricular (LV) stroke volume. To test their hypothesis that left atrial (LA) storage fraction is increased to compensate for impaired LV filling in the heart of aged subjects or with impaired LV ejection fraction, the authors studied 33 "normal" subjects and 25 patients with coronary artery disease. LA volume was measured by LA cineangiocardiography, and LV stroke volume and LV ejection fraction were measured by LV cineangiocardiography. To further evaluate the determinants of changes in LA storage fraction, they measured the ratio of LA active release volume to LV stroke volume, and the ratio of LA passive release volume to LV stroke volume. In "normal" subjects, LA storage fraction was increased with age (r = 0.584, P < 0.01). In patients with coronary artery disease, LA storage fraction was increased as LV ejection fraction was decreased (r = -0.525, P < 0.01). In both cases, LA active release fraction was significantly associated with changes in LA storage fraction rather than in LA passive release fraction. They conclude that LA storage fraction may be an important determinant of LV filling mainly through the LA active release fraction.

journal_name

Angiology

journal_title

Angiology

authors

Nishigaki K,Arakawa M,Miwa H,Kagawa K,Noda T,Ito Y

doi

10.1177/000331979404501108

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

953-62

issue

11

eissn

0003-3197

issn

1940-1574

journal_volume

45

pub_type

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