Do men and women respond differently to percutaneous renal artery interventions?

Abstract:

BACKGROUND:Women have higher risk of contrast-induced nephropathy than men. The purpose of this study was to determine the relative impact of gender on long-term renal function after percutaneous renal interventions (PRI). METHODS AND RESULTS:We included all patients undergoing PRI. Men (n = 72) and women (n = 28) had similar age, men had more diabetes, coronary and peripheral artery disease, higher serum creatinine and similar glomerular filtration rate (GFR), and prevalence of chronic kidney disease (CKD) stage > or =3 when compared with females. At follow-up, men had a significant improvement in GFR and systolic blood pressure, while females did not. The presence of severe CKD and male gender were the only predictors of long-term GFR improvement. CONCLUSION:Male patients and patients with poor baseline renal function showed an important benefit with PRI, suggesting that it is not too late for renal revascularization if properly indicated.

journal_name

Angiology

journal_title

Angiology

authors

Albertal M,Nau G,Padilla LT,Cura FA,Thierer J,Belardi JA

doi

10.1177/0003319709337306

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

216-21

issue

2

eissn

0003-3197

issn

1940-1574

pii

0003319709337306

journal_volume

61

pub_type

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