Abstract:
:The influence of long-term oral administration of buflomedil on regional cerebral blood flow was investigated in 10 patients with chronic cerebral infarction and mild to moderate mental deterioration. Patients were given 150 mg buflomedil three times daily for a period of eight weeks. Regional cerebral blood flow (rCBF) was measured in patients before they began buflomedil treatment and during the last week of treatment. The interval of the rCBF measurements in the control subjects (n = 12) ranged from seven to forty-eight days. Mental function in the patients studied was evaluated by use of Hasegawa's simple intelligence scale for the aged and Zung's self-rating depression scale, before and during the last week of buflomedil treatment. The results showed a mean increase in rCBF of 10.5% +/- 12.1% in the patient group. The control group demonstrated virtually no change in rCBF measurements. Improvements in the mental function scores of the buflomedil-treated group were noted, and 5 of the 10 patients reported improvement in subjective symptoms.
journal_name
Angiologyjournal_title
Angiologyauthors
Kobayashi S,Yamaguchi S,Okada K,Kitani M,Yamashita K,Shimote K,Tsunematsu Tdoi
10.1177/000331978803901102subject
Has Abstractpub_date
1988-11-01 00:00:00pages
934-41issue
11eissn
0003-3197issn
1940-1574journal_volume
39pub_type
杂志文章相关文献
ANGIOLOGY文献大全abstract::The surgical approach-of-choice for the management of popliteal artery aneurysms (PAAs) remains controversial. We compared the results of the medial (MA) and dorsal (posterior) surgical approach (DA). Fifty patients (44 males/6 females; median age [range]: 59 [49-84] years) treated for 58 atherosclerotic PAAs were stu...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319709355802
更新日期:2010-04-01 00:00:00
abstract::The objective of this study was to develop a method for the analytical assessment of arterial obstruction in conditions of Raynaud's phenomenon capable of providing diagnostic criteria. Numerous attempts have been made to determine and quantify arterial obstruction in terms of Doppler ultrasound measurements of arteri...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970005101202
更新日期:2000-12-01 00:00:00
abstract::Many recent studies have suggested that psoriasis, a chronic, inflammatory, immune-mediated skin disease, is associated with increased risk of cardiovascular disease (CVD). We aimed to compare arterial stiffness in psoriasis and control patient groups using the cardio-ankle vascular index (CAVI) and to determine wheth...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319716652284
更新日期:2017-08-01 00:00:00
abstract::Blood may provide superior cardioplegia compared with crystalloid cardioplegic solution. However, the results are controversial. This may be due to a leftward shift of the hemoglobin (Hb)-O2 dissociation curve induced by hypothermia, increasing the oxygen affinity for Hb. This effect may negate the potential benefit o...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978803900201
更新日期:1988-02-01 00:00:00
abstract::The aim of our study was to evaluate the sensitivity, the specificity, and the positive and negative predictive values of a recently developed computerized impedance plethysmography (CIP) in the diagnosis of deep vein thrombosis (DVT); 117 consecutive outpatients with a clinical suspicion of DVT were evaluated. After ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979004100709
更新日期:1990-07-01 00:00:00
abstract::The authors used the microcorrosion cast technique to study the localization and the role of pericytes in the microcirculation of skeletal muscle. Both fast twitch muscles, the tibialis anterior and the pectineus muscles, and a slow twitch one, the soleus muscle, were studied, because of morphological differences of t...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978503600708
更新日期:1985-07-01 00:00:00
abstract::We used the National Heart, Lung, and Blood Institute Limited Access Dataset of Prevention of Events with Angiotensin-Converting Enzyme Inhibition (PEACE) Trial (n = 8290) which included patients with stable coronary artery disease (CAD) and preserved ejection fraction (>40%). We identified risk factors for the develo...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319711398650
更新日期:2011-08-01 00:00:00
abstract::Modifications in transcutaneous oxygen pressure (TcPO2), induced by the administration of 3 mg/kg/day buflomedil chlorhydrate for seven days were evaluated in 12 subjects suffering from peripheral vascular disease (PVD). After the treatment a significant increase in TcPO2 basal values was observed in Stage III and Sta...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904000607
更新日期:1989-06-01 00:00:00
abstract::Direct coronary stenting without balloon predilation has the potential benefits of a reduced risk of extended dissections, reduced fluoroscopy exposure, reduced procedural time, and potential cost savings. The purpose of the study was to compare the effects of angiographically successful direct stent implantation and ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970405500503
更新日期:2004-09-01 00:00:00
abstract::Activated protein C resistance (APC-R) is the most common inherited cause of clinically apparent venous thromboembolism. Previous data indicate that left atrial thrombus (LAT) formation is a common complication in mitral stenosis (MS) and a hypercoagulable state exists in these patients. The aim of this study was to i...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970005101008
更新日期:2000-10-01 00:00:00
abstract::The authors previously reported a new syndrome, angiotensin-converting enzyme dysfunction syndrome (ACEDS), which is clinically characterized by mild systemic hypertension, a hypokalemic alkalosis, and hyperreninism with a high concentration of angiotensin-I (ANG-I), a normal angiotensin-II (ANG-II) value, and a norma...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978803900110
更新日期:1988-01-01 00:00:00
abstract:UNLABELLED:From a sample of 1,824 patients with coronary artery disease (CAD) at the time of their interview, 827 males (M) and 251 females (F), had at least one distinct recurrence of their disease--some type of angina (A) or myocardial infarction (MI). In these patients, the age and type of CAD at the first and secon...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904000709
更新日期:1989-07-01 00:00:00
abstract::Patients with mitral stenosis have usually blunted pulmonary venous (PV) flow, because of decreased mitral valve area and diastolic dysfunction. The authors compared changes in Doppler PV velocities by using transesophageal echocardiography (TEE) against hemodynamics parameters before and after mitral balloon valvotom...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970205300310
更新日期:2002-05-01 00:00:00
abstract::Advanced chronic heart failure (ACHF) patients often require inotropes before transplantation or ventricular assist device implantation. Milrinone, an inotrope and vasodilator, may accumulate in cardiorenal syndrome with serious adverse effects. We investigated the potential for therapeutic drug monitoring of milrinon...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319713485808
更新日期:2014-04-01 00:00:00
abstract::Systemic arteriovenous (AV) fistulas are a rare but correctable cause of hyperkinetic circulation and congestive heart failure. They are generally due to catheterization procedures, surgery, trauma, or aneurysms. A case of truly spontaneous AV fistula between left subclavian artery and left innominate vein is describe...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979204300807
更新日期:1992-08-01 00:00:00
abstract::Axillosubclavian vein thrombosis is seen relatively infrequently in clinical practice when compared with lower limb deep-venous thrombosis; however, it is a condition that can result in significant morbidity if managed suboptimally. A multimodal treatment approach has been increasingly adopted with thrombolysis and/or...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/0003319707305917
更新日期:2008-02-01 00:00:00
abstract::We investigated the relation between diabetic autonomic neuropathy (DAN) and left ventricular (LV) function in 59 patients with type 2 diabetes mellitus (T2DM) free of coronary artery disease (CAD) or hypertension. Diabetic autonomic neuropathy was established by ≥2 abnormal autonomic nervous function tests. Left vent...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319713510966
更新日期:2014-11-01 00:00:00
abstract::A 76-year-old man without any prior history of abnormal urinalysis findings or renal insufficiency demonstrated mild renal dysfunction after coronary bypass graft surgery (CABG). Two months after CABG, pain and blueness in the toes (blue toe syndrome) appeared and, the serum creatinine level (S-Cr) increased from 1.2 ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970605700316
更新日期:2006-05-01 00:00:00
abstract::Systolic time intervals and heart sounds were studied in twenty patients with left bundle branch block. A definite cause for the organic heart disease was not ascertained. Abnormal duration of the electromechanical systole (Q-A2), due to a prolongation both of the preejection period (PEP) and of the Q-M1 intervals, wa...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977602700705
更新日期:1976-07-01 00:00:00
abstract::Acute peripheral occlusive arterial disease is an important cause of morbidity and mortality, particularly among older persons. Catheter-directed thrombolytic therapy is the treatment of choice but has limitations: long lytic times, occlusions refractory to thrombolysis, and a high rate of restenosis. We conducted a p...
journal_title:Angiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000331970005101104
更新日期:2000-11-01 00:00:00
abstract::The clinical angiographic, and available autopsy data of 32 patients with cardiomyopathy with cardiomegaly were reviewed. Twenty-six patients had alcoholic cardiomyopathy. Of these, 20 patients had patient coronary arteries, and 6 had significant occlusive coronary artery disease. Six patients denied any history of ex...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978103200707
更新日期:1981-07-01 00:00:00
abstract::The possibility that a familial background of hypertension might influence the blood pressure response to a calcium entry blocker was evaluated in 15 normotensive relatives of patients with essential hypertension and 18 normotensive subjects with no family history of hypertension. Under control conditions, blood press...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978703801203
更新日期:1987-12-01 00:00:00
abstract::The transradial approach (TRA) has been used as access site for percutaneous coronary intervention (PCI) for years. However, no large sample study has evaluated the effect of TRA in elderly patients. A total of 1098 elderly patients (age ≥ 75 years) who underwent PCI by TRA or transfemoral approach were recruited. A 1...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319714535971
更新日期:2015-05-01 00:00:00
abstract::The authors investigated the time-dependent action of atorvastatin and simvastatin on oxidative stress and cytokine levels immediately after the start of treatment. These factors play a role in endothelial dysfunction. Hyperlipidemic patients (n = 132) were assigned to treatment with 40 mg atorvastatin, 40 mg simvasta...
journal_title:Angiology
pub_type: 杂志文章,随机对照试验
doi:10.1177/000331970605700212
更新日期:2006-03-01 00:00:00
abstract::Timolol is a new beta blocker with cardioselective properties. A single blind controlled study was performed to assess the efficacy of timolol maleate in doses of 10 to 30 mg per day in 20 patients affected by stable angina pectoris. The patients received a placebo for a baseline period of 2 weeks, followed by 12 week...
journal_title:Angiology
pub_type: 临床试验,杂志文章
doi:10.1177/000331978003100403
更新日期:1980-04-01 00:00:00
abstract::Increased mean platelet volume (MPV) is associated with poor clinical outcome in patients with acute coronary syndrome. We evaluated the predictive role of MPV in young patients with acute myocardial infarction (AMI). This study includes 373 patients who presented to our hospital with AMI (group 1: 134 young patients,...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712448834
更新日期:2013-07-01 00:00:00
abstract::The relationship between echocardiographically measured epicardial fat thickness (EFT) and plasma concentrations of leptin, ghrelin, and adiponectin has not been evaluated in patients with noncachectic heart failure (HF). Patients with noncachectic HF and age- and sex-matched controls did not differ significantly in E...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712447978
更新日期:2013-04-01 00:00:00
abstract::Endothelial cell-specific molecule 1 ([ESM-1], endocan) is a new biomarker of endothelial dysfunction, which may be involved in the pathogenesis of atherosclerosis and stress hyperglycemia in patients with acute ST-segment elevation myocardial infarction (STEMI). Therefore, we investigated serum ESM-1 levels in patien...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319715621996
更新日期:2016-10-01 00:00:00
abstract::Different patterns of flow and valve gradients can lead to diagnostic uncertainty about the severity of aortic stenosis (AS). Consecutive patients with severe AS (valve area <1 cm(2)) underwent echocardiography and computed tomography. Patients were classified into 4 groups (high-gradient/normal flow [HGNF], high-grad...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319715611804
更新日期:2016-08-01 00:00:00
abstract::Part I of this review discussed pharmacotherapy of primary pulmonary hypertension (PHT). Part II describes the value and limitations of oxygen and vasodilator therapy of secondary PHT, focusing on patients with PHT associated with selected connective tissue disease and chronic nonthrombotic hypoxic lung disease. ...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/000331979404500902
更新日期:1994-09-01 00:00:00