Abstract:
:High-mobility group box 1 (HMGB-1) is a nuclear protein physiologically involved in the maintaining of DNA structure in the nucleus. When tissue damage occurs, necrotic cells as well as inflammatory cells, once activated, release this protein in circulating blood, where it seems to exert a direct proinflammatory action. Thus, HMGB-1 might be involved in the pathophysiology of several diseases, including cardiovascular disease. However, the experimental evidence has not yet clarified its cardiovascular role which is still debated. Specifically, it is still not completely resolved whether HMGB-1 plays a protective or detrimental role on cardiovascular function. In this review, we consider the role of HMGB-1 in pathological conditions and comment on the role of this protein in the cardiovascular disease.
journal_name
Angiologyjournal_title
Angiologyauthors
Cirillo P,Giallauria F,Di Palma V,Maresca F,Ziviello F,Bevilacqua M,Vigorito C,Trimarco Bdoi
10.1177/0003319712458032subject
Has Abstractpub_date
2013-07-01 00:00:00pages
343-55issue
5eissn
0003-3197issn
1940-1574pii
0003319712458032journal_volume
64pub_type
杂志文章,评审相关文献
ANGIOLOGY文献大全abstract::To examine alterations in control functions of the heart, which may account for the pathophysiologic conditions precipitating coronary arterial spasm, heart rate response to exercise in vasospastic angina was evaluated by using our previously developed method of frequency analysis. We also examined the effects of thre...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978503600102
更新日期:1985-01-01 00:00:00
abstract::Six cases of coronary artery fistulae surgically treated are presented. All patient but one was male; the ages varied from 4 to 44 years. The fistulae originated from the left coronary artery in three cases from the right in two cases and from both arteries in one case. The draining heart chambers were the right atriu...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977602701108
更新日期:1976-11-01 00:00:00
abstract::The junctions between endothelial cells in lymph capillaries may have different degrees of complexity and have been classified as three types: "end to end" (EE), "overlapping" (OVL), and "interdigitating" (ID). Under normal conditions, the more complex junction types (ID and OVL) are more frequent than the simple type...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979104201109
更新日期:1991-11-01 00:00:00
abstract::The hypothesis that blood rheology is of prognostic value in patients with arteriosclerotic diseases was tested in a prospective study of 843 patients at a rehabilitation clinic. They were tested for blood serum and plasma viscosity, hematocrit, fibrinogen, red cell aggregation and deformability, erythrocyte sedimenta...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979104201204
更新日期:1991-12-01 00:00:00
abstract::Vascular malformations of the mediastinum including mediastinal lymphangioma are exceedingly rare in adults. A resected case of mediastinal cystic lymphangioma (cystic hygroma) that presented with acute onset of retrosternal chest pain is reported in a 45-year-old man. Cystic hygromas are benign cysts frequently disco...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970405500513
更新日期:2004-09-01 00:00:00
abstract::Abdominal aortic aneurysm is common. The aim of this study was to assess the effect of smoking on prevalence and management. Patients attending the vascular unit and appropriate controls were prospectively recruited. A smoking history revealed tobacco exposure in pack years. Serum cotinine was assessed biochemically. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319708318380
更新日期:2009-02-01 00:00:00
abstract::A 78-year-old man was admitted to hospital with heart failure and chronic bronchitis. A computed tomographic scan of the chest incidentally demonstrated bilateral abnormal vessels near the left atrium. Selective angiography showed that both internal mammary arteries and bronchial arteries communicated with the pulmona...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979804901010
更新日期:1998-09-01 00:00:00
abstract::This study assesses measurement variation in the measurement of ankle systolic blood pressure (ABP) when measured with Doppler ultrasound and with the strain gauge method. Ninety-seven patients were included. ABP was measured with Doppler ultrasound and with the strain gauge method. The methods were compared graphical...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319707308198
更新日期:2008-06-01 00:00:00
abstract::"Micro" and "macro" peripheral embolisms during coronary angiography have been described. In all these cases, the aorta or the left heart chambers have been the source of embolus. A patient who during coronary angiography for acute inferior myocardial infarction experienced acute embolism of the left common femoral ar...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970105200709
更新日期:2001-07-01 00:00:00
abstract::The present study aimed to investigate the long-term effects of transradial procedures on the radial artery diameter and vasodilator properties. The study included a total of 35 patients (28 males and 7 females) who underwent left transradial coronary angiography with an appropriate indication. The radial artery diame...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319712458450
更新日期:2013-10-01 00:00:00
abstract::Thirty-four patients with symptoms suggesting mitral valve prolapse were evaluated by M-mode echocardiography, real time, two-dimensional, phase array echocardiography, and cardiac catheterization. Ten of these patients had unequivocal evidence of mitral valve prolapse during cardiac catheterization. This diagnosis wa...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978003100307
更新日期:1980-03-01 00:00:00
abstract::Ostial left main coronary stenosis has a poor prognosis and increased mortality rate with coronary arteriography. Due to its anatomic location, visualization of the stenosis may be difficult. A high index of suspicion based upon only a few signs should prompt the physician to perform certain maneuvers to obtain the co...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978603700809
更新日期:1986-08-01 00:00:00
abstract::The syndrome of nonejection click-late systolic murmur and mitral valve prolapse is reviewed. A patient with this syndrome is reported. Physical findings, important diagnostic studies, and possible complications are discussed. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977602701006
更新日期:1976-10-01 00:00:00
abstract::Two cases of catheter embolization from implanted venous access devices are reported and the available literature is reviewed. The catheter from an implanted venous access device migrated into the right heart after slippage of the O-ring, which attaches the catheter to the infusion port. The distal 6 cm of an infusion...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904000413
更新日期:1989-04-01 00:00:00
abstract::A subgroup of patients with normal stress myocardial perfusion imaging (MPI) have obstructive coronary artery disease (CAD) on coronary computed tomographic angiography (CCTA). A retrospective study was performed to identify factors associated with obstructive CAD in patients with normal MPI. Bivariate differences bet...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319711415392
更新日期:2012-05-01 00:00:00
abstract::Swallow syncope is usually caused by organic or functional disorders of the esophagus due to abnormal vasovagal reflex. In elderly patients this situation could be confused with postprandial hypotension. We present a case of an elderly patient who presented with swallow syncope that was caused by a waist in the midpor...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319706295514
更新日期:2007-02-01 00:00:00
abstract::Under certain conditions laser Doppler flowmeter (LDF) signals obtained from the finger pulp may appear very similar to those obtained by use of a direct current (dc) photoplethysmograph (PPG). A combined LDF/PPG system was used in conjunction with a circumference strain gauge as an index of volume change to identify ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978803900906
更新日期:1988-09-01 00:00:00
abstract::The angiographic appearance of arterio-venous shunting has been reported in one previous case of a patient with acute severe transplant rejection. Two additional cases are presented here. In the first the arteriovenous shunting is massive, and the venous filling is within the first second of the study. In the second t...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977802900106
更新日期:1978-01-01 00:00:00
abstract::Systolic pressures and skin temperatures were studied in 23 patients with severe Raynaud's syndrome who were given oral phenoxybenzamine. There was a relationship between the measurements and the severity of the disease. Statistically significant correlation was found between the measurements and the time for healing ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978103200502
更新日期:1981-05-01 00:00:00
abstract::We assessed the clinical echocardiograhic, hematological, and biochemical parameters in patients with dilated cardiomyopathy (DCMP) and control individuals mainly focusing on the mean platelet volume (MPV) in terms of DCMP and left ventricle (LV) thrombus formation. Consecutive patients (n = 251) with DCMP and 266 pat...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319711435146
更新日期:2012-10-01 00:00:00
abstract::Changes in plasma fibrinogen concentrations (PFC) and relative plasma viscosity (RPV) were investigated in 61 Nigerian Africans while they were being treated for essential hypertension. The association of these hemorheologic variables with blood pressure was examined. An analogous study was done on 30 normotensive con...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979204301005
更新日期:1992-10-01 00:00:00
abstract::The effect of enalapril on cerebral blood flow (CBF) was studied in 11 patients with chronic heart failure (NYHA II or III, dilated cardiomyopathy in 6 and old myocardial infarction in 5). CBF was evaluated by analyzing the Patlak-Plot curve obtained from radionuclide angiography with technetium-99m hexamethylpropylen...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979704800806
更新日期:1997-08-01 00:00:00
abstract::Intravascular ultrasound (IVUS) frequently reveals plaque formation at sites with a normal angiographic appearance. However, whether angiographically normal coronary arteries undergo adaptive expansion in vivo remains uncertain. The authors studied 12 patients (11 men, 1 woman; mean age fifty-three +/- ten years [mean...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700804
更新日期:1996-08-01 00:00:00
abstract::Pulmonary edema of non-cardiac origin is usually an urgent clinical problem, which has recently increased in frequency throughout the world in the past few years. This is partly due to sociological factors and to pre-eminent advances in industrial technology. Recent severe massive toxic gas explosions have had nationa...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978603700603
更新日期:1986-06-01 00:00:00
abstract::Four instances of mediastinal wound infection occurred in 100 patients who underwent bilateral internal mammary artery (IMA) mobilization for coronary bypass. Debridement of 3--5 mm of the sternal edges was performed 6--18 days after the primary operation, and 2 patients required additional, anatomically limited debri...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977802900403
更新日期:1978-04-01 00:00:00
abstract::Nine patients with alcoholic cardiomyopathy and 8 patients with mitral stenosis were studied by right and left heart catheterization. Hemodynamic observations were made during control period and during the infusion of phentolamine at a rate of 0.3 mg per minute. The patients with the cardiomyopathy responded to phento...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977903000708
更新日期:1979-07-01 00:00:00
abstract::Modifications in transcutaneous oxygen pressure (TcPO2), induced by the administration of 3 mg/kg/day buflomedil chlorhydrate for seven days were evaluated in 12 subjects suffering from peripheral vascular disease (PVD). After the treatment a significant increase in TcPO2 basal values was observed in Stage III and Sta...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904000607
更新日期:1989-06-01 00:00:00
abstract::This study consists of a retrospective evaluation of microbiologic, echocardiographic, and clinical characteristics of patients with infective endocarditis seen at Türkiye Yüksek Ihtisas and SSK Ihtisas Hospitals during the previous 5 years to provide a basis for comparison with other series. The study was performed r...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970205300210
更新日期:2002-03-01 00:00:00
abstract::Neointimal hyperplasia is in the forefront in in-stent restenosis. Prevention of in-stent restenosis is possible by reducing and inhibiting the hyperplasia of smooth muscle cells. The authors planned this study to test the hypothesis that when administered orally, mycophenolate mofetil (MMF) could inhibit in-stent neo...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319706293120
更新日期:2006-10-01 00:00:00
abstract::An eighty-one-year-old woman received quinidine in order to convert atrial fibrillation to a sinus rhythm. The patient developed a prolonged QT interval on the EKG, as well as episodes of torsade de pointes. With the administration of intravenous magnesium sulfate, the abnormal rhythm was suppressed within minutes. Th...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979004100712
更新日期:1990-07-01 00:00:00