Diagnosis of vasospastic angina by analysis of heart rate response to exercise: effects of different levels of work load.

Abstract:

:To examine alterations in control functions of the heart, which may account for the pathophysiologic conditions precipitating coronary arterial spasm, heart rate response to exercise in vasospastic angina was evaluated by using our previously developed method of frequency analysis. We also examined the effects of three different levels of work load on the heart rate response to treadmill exercise in 9 patients with vasospastic angina and 7 normal controls: stage 1 (2.5 Km/h, 10%), stage 3 (4.5 Km/h, 10%), and stage 5 (5.5 Km/h, 14%). The transfer function of heart rate control in vasospastic angina was characteristically different from that in normal controls: lower gain and more delayed phase angle of the system. Although this abnormality was observed in every test at 3 different levels of work load, the abnormality was more striking in tests at lower levels of work load: stage 1 or 3. The moderately light exercise test at stage 3 is most suitable as a test for detecting abnormal heart rate response to exercise in vasospastic angina because the exercise test at stage 1 had a poor S/N ratio.

journal_name

Angiology

journal_title

Angiology

authors

Sato I,Hasegawa Y,Ohe T,Funahashi T,Tomobuchi Y,Shimomura K

doi

10.1177/000331978503600102

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

9-18

issue

1

eissn

0003-3197

issn

1940-1574

journal_volume

36

pub_type

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