The Effect of Residing Altitude on Levels of High-Density Lipoprotein Cholesterol: A Pilot Study From the Omani Arab Population.

Abstract:

:Lower mortality rates from coronary heart disease and higher levels of serum high-density lipoprotein cholesterol (HDL-C) have been observed in populations residing at high altitude. However, this effect has not been investigated in Arab populations, which exhibit considerable genetic homogeneity. We assessed the relationship between residing altitude and HDL-C in 2 genetically similar Omani Arab populations residing at different altitudes. The association between the levels of HDL-C and other metabolic parameters was also investigated. The levels of HDL-C were significantly higher in the high-altitude group compared with the low-altitude group. Stepwise regression analysis showed that altitude was the most significant factor affecting HDL-C, followed by gender, serum triglycerides, and finally the 2-hour postprandial plasma glucose. This finding is consistent with previously published studies from other populations and should be taken into consideration when comparing cardiovascular risk factors in populations residing at different altitudes.

journal_name

Angiology

journal_title

Angiology

authors

Al Riyami NB,Banerjee Y,Al-Waili K,Rizvi SG,Al-Yahyaee S,Hassan MO,Albarwani S,Al-Rasadi K,Bayoumi RA

doi

10.1177/0003319714544355

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

568-73

issue

6

eissn

0003-3197

issn

1940-1574

pii

0003319714544355

journal_volume

66

pub_type

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