Abstract:
:Lower mortality rates from coronary heart disease and higher levels of serum high-density lipoprotein cholesterol (HDL-C) have been observed in populations residing at high altitude. However, this effect has not been investigated in Arab populations, which exhibit considerable genetic homogeneity. We assessed the relationship between residing altitude and HDL-C in 2 genetically similar Omani Arab populations residing at different altitudes. The association between the levels of HDL-C and other metabolic parameters was also investigated. The levels of HDL-C were significantly higher in the high-altitude group compared with the low-altitude group. Stepwise regression analysis showed that altitude was the most significant factor affecting HDL-C, followed by gender, serum triglycerides, and finally the 2-hour postprandial plasma glucose. This finding is consistent with previously published studies from other populations and should be taken into consideration when comparing cardiovascular risk factors in populations residing at different altitudes.
journal_name
Angiologyjournal_title
Angiologyauthors
Al Riyami NB,Banerjee Y,Al-Waili K,Rizvi SG,Al-Yahyaee S,Hassan MO,Albarwani S,Al-Rasadi K,Bayoumi RAdoi
10.1177/0003319714544355subject
Has Abstractpub_date
2015-07-01 00:00:00pages
568-73issue
6eissn
0003-3197issn
1940-1574pii
0003319714544355journal_volume
66pub_type
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