Abstract:
:Intravascular ultrasound (IVUS) frequently reveals plaque formation at sites with a normal angiographic appearance. However, whether angiographically normal coronary arteries undergo adaptive expansion in vivo remains uncertain. The authors studied 12 patients (11 men, 1 woman; mean age fifty-three +/- ten years [mean +/- SD]) with focal coronary stenosis. Sixty IVUS images from angiographically normal coronary segments were analyzed (14 left main, 44 left anterior descending, and 2 left circumflex coronary arteries). The mean percent area stenosis was 36 +/- 5% and the circular shape factor of the lumen cross section averaged 0.97 +/- 0.02. Both total arterial area and internal elastic lamina area increased as the plaque area expanded (y = 2.13x + 8.07, r = 0.87, P = 0.0001; y = 2.06x + 4.57, r = 0.87, P = 0.0001, respectively), suggesting that for every 1 mm2 increase in plaque area, the total arterial area increased by approximately 2.13 mm2 and the internal elastic lamina area increased by approximately 2.06 mm2. The lumen area also increased as the plaque area expanded (y = 1.06x + 4.57, r = 0.68, P = 0.0001), suggesting that for every 1 mm2 increase in plaque area, the lumen area increased by approximately 1.06 mm2. The medial area did not correlate with the plaque area (r = 0.15, P = 0.26). Thus, compensatory enlargement precedes development of angiographically, detectable coronary atherosclerosis. Furthermore, in early stages of atherosclerosis, arterial enlargement may overcompensate for plaque area. The reduction of the total medial mass does not appear to contribute to the mechanism of compensatory enlargement.
journal_name
Angiologyjournal_title
Angiologyauthors
Nakamura Y,Takemori H,Shiraishi K,Inoki I,Sakagami M,Shimakura A,Usuda K,Kubota K,Takata S,Kobayashi Kdoi
10.1177/000331979604700804subject
Has Abstractpub_date
1996-08-01 00:00:00pages
775-81issue
8eissn
0003-3197issn
1940-1574journal_volume
47pub_type
杂志文章相关文献
ANGIOLOGY文献大全abstract::Intravenous naftidrofuryl has been shown to improve transcutaneous oxygen pressure values in patients with severe ischemia of the lower limbs who were considered unsuitable for reconstructive surgery. Although it did not alter the outcome in patients with rest pain, the clinical impression is that it afforded symptoma...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904001007
更新日期:1989-10-01 00:00:00
abstract::Pirmenol hydrochloride (CI-845), a new orally effective antiarrhythmic agent, has undergone a comprehensive preclinical safety evaluation program. Repeated dose studies to evaluate chronic toxicity in rodents revealed few drug-related findings. A dose-related body weight gain suppression occurred in mice receiving up ...
journal_title:Angiology
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract::Serum gamma-glutamyltransferase (GGT) activity is a marker of oxidative stress and activity is associated with cardiovascular disease. Carotid intima-media thickness (IMT) is a noninvasive predictor of atherosclerosis. We investigated the association between serum GGT activity and carotid IMT. Fifty-five persons who h...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319710386471
更新日期:2011-02-01 00:00:00
abstract::The electrocardiographic abnormalities found in 100 patients with acute cerebrovascular disease and previously normal hearts are described. The abnormalities were more often seen in patients with intracerebral and subarachnoid hemorrhages. The most common changes were Q-Tc Prolongation and ST segment and T wave abnorm...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979004100902
更新日期:1990-09-01 00:00:00
abstract::There are only a few data on the relationship of insulin-like growth factor-1 (IGF-1), implicated in glucose homeostasis, and C-reactive protein (CRP), a measure of subclinical systemic inflammation, in patients with the metabolic syndrome (MetS). The authors investigated, in a cross-sectional design, the correlation ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970605700306
更新日期:2006-05-01 00:00:00
abstract::We evaluated the outcomes of revascularization in patients with chronic limb-threatening ischemia (CLTI) treated in real-world settings. This is a prospective multicenter cohort study with 12-month follow-up enrolling patients (n = 287) with CLTI undergoing open, endovascular, or hybrid lower extremity revascularizati...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319720980619
更新日期:2021-01-07 00:00:00
abstract::Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this stu...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319714523113
更新日期:2015-02-01 00:00:00
abstract::Four instances of mediastinal wound infection occurred in 100 patients who underwent bilateral internal mammary artery (IMA) mobilization for coronary bypass. Debridement of 3--5 mm of the sternal edges was performed 6--18 days after the primary operation, and 2 patients required additional, anatomically limited debri...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977802900403
更新日期:1978-04-01 00:00:00
abstract::Elevated plasma levels of asymmetric dimethylarginine (ADMA) are prevalent in patients with hypercholesterolemia and coronary artery disease. A total of 83 patients with hypercholesterolemia and angiographically documented mild coronary artery stenosis were randomized to rosuvastatin treatment (20 mg) or atorvastatin ...
journal_title:Angiology
pub_type: 杂志文章,随机对照试验
doi:10.1177/0003319713507333
更新日期:2014-10-01 00:00:00
abstract::Acute peripheral occlusive arterial disease is an important cause of morbidity and mortality, particularly among older persons. Catheter-directed thrombolytic therapy is the treatment of choice but has limitations: long lytic times, occlusions refractory to thrombolysis, and a high rate of restenosis. We conducted a p...
journal_title:Angiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000331970005101104
更新日期:2000-11-01 00:00:00
abstract::Transcutaneous electrical nerve stimulation (TENS) afforded significant relief of the pain associated with acute and recurrent thrombophlebitis in 90% of 39 patients so treated. The method is simple to administer, noninvasive, and apparently free of side effects. It can be self-administered by the patient after approp...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331977903000404
更新日期:1979-04-01 00:00:00
abstract::The aim of this study was to investigate the behavior of plasma endothelin-1 (ET-1) in 23 patients with acute myocardial infarction, complicated and uncomplicated by left ventricular failure, and treated with and without thrombolytic agents. ET-1 was measured on admission; on days 2, 3, and 5; and again on discharge. ...
journal_title:Angiology
pub_type: 临床试验,杂志文章
doi:10.1177/000331979905000803
更新日期:1999-08-01 00:00:00
abstract::Acute mesenteric ischemia is a rare but serious complication of open heart surgery. Between January 2009 and January 2012, 1360 adult patients underwent open heart surgery with cardiopulmonary bypass at our institution; 29 patients presented gastrointestinal complications. Eight patients developed acute mesenteric isc...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319713482357
更新日期:2014-05-01 00:00:00
abstract::The etiologies of venous leg ulcers have been well known for millennia, and yet there remains no simple solution to this very common problem. Achieving closure of venous leg ulcers is often a lengthy process that is further complicated by the presence of significant comorbidities. The authors present data on healing v...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970605700202
更新日期:2006-03-01 00:00:00
abstract::Nitroglycerin has been the mainstay of the medical management of angina pectoris for over 100 years. The long-held clinical impression of the efficacy of nitroglycerin has now been clearly documented in controlled clinical trials designed to evaluate objective response to antianginal agents. Advances in scientific met...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/000331978303400101
更新日期:1983-01-01 00:00:00
abstract::To evaluate the aortic wall sclerosis in patients with coronary artery disease (CAD), the authors measured the aortic distensibility (AD) at the ascending and descending aorta by using cine magnetic resonance (MR). Cine MR was performed in 15 patients with CAD and 15 normal controls (NCs). Patients with CAD had angiog...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979604700206
更新日期:1996-02-01 00:00:00
abstract::The aim of this study was to analyze the left ventricular (LV) geometric changes occurring in chronic pressure overload due to valvular aortic stenosis (AS). Fifty-six adult patients (30 women, 26 men, mean age seventy-two +/- nine years, range forty-five to eighty-five years) with isolated AS (mean valve area by Dopp...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979404501206
更新日期:1994-12-01 00:00:00
abstract::Changes in plasma fibrinogen concentrations (PFC) and relative plasma viscosity (RPV) were investigated in 61 Nigerian Africans while they were being treated for essential hypertension. The association of these hemorheologic variables with blood pressure was examined. An analogous study was done on 30 normotensive con...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979204301005
更新日期:1992-10-01 00:00:00
abstract::A 38-year-old, previously healthy man presented with flank pain after competing in a marathon. Initial laboratory tests and urinalysis were essentially normal. Both contrast enhanced-computed tomography and magnetic resonance angiography showed an infarcted region of the left lower kidney without renal artery dissecti...
journal_title:Angiology
pub_type: 杂志文章,评审
doi:10.1177/0003319707310278
更新日期:2009-02-01 00:00:00
abstract::Shortly after Dreyfus and his colleagues demonstrated that procainamide was metabolized by acetylation to N-acetylprocainamide (NAPA), Drayer, Reidenberg and Sevy reported that NAPA had antiarrhythmic activity in an animal model. We confirmed these findings and found that plasma levels of NAPA were high enough to warr...
journal_title:Angiology
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract::The patient's position during laparoscopic surgery can have a clinically relevant effect on lower limb and splanchnic circulation; this factor has not yet been investigated with respect to oxidative stress markers. In order to assess this effect, a prospective clinical trial was designed wherein 2 groups of patients w...
journal_title:Angiology
pub_type: 临床试验,杂志文章
doi:10.1177/000331970505600414
更新日期:2005-07-01 00:00:00
abstract::A 13-year-old girl was successfully recuperated from cardiopulmonary arrest shortly after running 80 m in a competition. The electrocardiogram, echocardiogram and 123I-MIBG myocardial scintigraphic imaging indicated myocardial ischemia in the anteroseptal wall of the left ventricle. Coronary angiography during the rec...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331970305400214
更新日期:2003-03-01 00:00:00
abstract::Endothelial cell-specific molecule 1 (ESM-1; endocan) is expressed by endothelial cells, and it can be overexpressed in diabetic patients. However, little is known concerning diabetic patients with acute ST-segment elevation myocardial infarction (STEMI). Therefore, we assessed serum ESM-1 level in patients having typ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319716634581
更新日期:2017-01-01 00:00:00
abstract::The Authors describe a case of arteritis of the lower limbs in a woman, in which the clinico-angiographical features were suggestive for Buerger's disease, and this was confirmed by histological examination of the left posterior tibial artery. A bilateral lumbar sympathectomy was effective at least in slowing the cour...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978503600308
更新日期:1985-03-01 00:00:00
abstract::Hyperlipidemia is an important modifiable risk factor of coronary heart diseases. So far, several studies, have indicated the beneficial effects of nuts on plasma lipid profile. Previously, in a pilot study the authors have shown that administration of 20 g/day of Persian walnut (Juglans regia L.) for 8 weeks could de...
journal_title:Angiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000331970305400404
更新日期:2003-07-01 00:00:00
abstract::Pentoxifylline (PF), known to increase red blood cell (RBC) deformability, has recently attracted much attention because of its possible effect of reducing capillary resistance. There has been practically no reliable demonstration of an increase in capillary blood flow by this drug. This study was intended to examine ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978103201103
更新日期:1981-11-01 00:00:00
abstract::Although the diagnosis of AIDS-associated heart disease is becoming routine, its treatment has not been reported except in anecdote. Also, it has been unclear whether the odds of successful treatment are altered because of the presence of cardiac involvement per se. This communication reports the authors' treatment of...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978904001106
更新日期:1989-11-01 00:00:00
abstract::Thirty patients with intermittent claudication (IC) and treated diabetes mellitus and 30 age- and gender-matched nondiabetic claudicants underwent a vascular examination by noninvasive ultrasound methods (continuous-wave Doppler, duplex scanner). The ankle/arm systolic pressure index did not differ in the two groups. ...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331979104200406
更新日期:1991-04-01 00:00:00
abstract::The calcium-blocking agent nifedipine, which possesses vasodilating potency, was tested in 8 patients with peripheral arterial insufficiency. 10 mg sublingually significantly decreased systolic arm and ankle blood pressure. Neither blood flow nor local peripheral resistance in the calf and the forefoot at rest and the...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/000331978303400106
更新日期:1983-01-01 00:00:00
abstract::We investigated the association between atherosclerosis of the thoracic aorta and the severity and extent of coronary atherosclerosis detected by multidetector computed tomography (MDCT) coronary angiography. In 122 patients, atherosclerotic plaque was scored from 0 to 4 points by the percentage of the luminal surface...
journal_title:Angiology
pub_type: 杂志文章
doi:10.1177/0003319710362976
更新日期:2010-10-01 00:00:00