Abstract:
:The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs ( P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (β-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.
journal_name
Angiologyjournal_title
Angiologyauthors
Tyrovolas S,Polychronopoulos E,Mariolis A,Piscopo S,Valacchi G,Makri K,Zeimbekis A,Tyrovola D,Bountziouka V,Gotsis E,Metallinos G,Tur JA,Matalas A,Lionis C,Haro JM,Panagiotakos DBdoi
10.1177/0003319716642140subject
Has Abstractpub_date
2017-02-01 00:00:00pages
124-131issue
2eissn
0003-3197issn
1940-1574pii
0003319716642140journal_volume
68pub_type
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