Abstract:
:Unstable angina and Q wave myocardial infarction are associated with intraluminal coronary thrombosis, a process to which impaired fibrinolysis may contribute. The authors examined the extrinsic fibrinolytic system, including tissue plasminogen activator antigen, plasminogen activator inhibitor activity and antigen, and euglobulin clot lysis time before and after venous occlusion in 56 patients undergoing coronary angiography for chest pain syndromes and in 16 healthy controls. Fibrinolysis variables were similar (with greater than 95% confidence) in the patients with thrombus-associated coronary syndromes as compared with those with chest pain syndromes not due to coronary thrombosis. These fibrinolytic variables were also similar to those in patients without coronary artery disease and in healthy controls. Their data suggest that defective fibrinolysis is not involved, at least systemically, in the pathogenesis of thrombus-associated coronary artery syndromes.
journal_name
Angiologyjournal_title
Angiologyauthors
Meyers DG,Haire WD,Rasmussen JK,Boyd EJdoi
10.1177/000331979104200707subject
Has Abstractpub_date
1991-07-01 00:00:00pages
561-7issue
7eissn
0003-3197issn
1940-1574journal_volume
42pub_type
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