Abstract:
:We suggest a new, easily applicable way of myocardial hypertrophy induction in rats. Forty randomized age-matched male Wistar rats were divided into 2 groups of 20 each: a control group and an orally administered fludrocortisone/salt group. Myocardial hypertrophy was estimated by measuring body weight, heart-weight-to-body-weight ratio and ventricular free wall thickness. Moderate myocardial hypertrophy without heart failure was established in fludrocortisone/salt group in 4 weeks. Our method is effective and low cost, and it provides a model of hypertrophic heart.
journal_name
Angiologyjournal_title
Angiologyauthors
Voucharas C,Tagarakis G,Lazou A,Triposkiadis F,Tsilimingas Ndoi
10.1177/0003319711423529subject
Has Abstractpub_date
2012-08-01 00:00:00pages
416-9issue
6eissn
0003-3197issn
1940-1574pii
0003319711423529journal_volume
63pub_type
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