Experimental cardiac hypertrophy induced by oral administration of mineralocorticoid and saline in rats.


:We suggest a new, easily applicable way of myocardial hypertrophy induction in rats. Forty randomized age-matched male Wistar rats were divided into 2 groups of 20 each: a control group and an orally administered fludrocortisone/salt group. Myocardial hypertrophy was estimated by measuring body weight, heart-weight-to-body-weight ratio and ventricular free wall thickness. Moderate myocardial hypertrophy without heart failure was established in fludrocortisone/salt group in 4 weeks. Our method is effective and low cost, and it provides a model of hypertrophic heart.






Voucharas C,Tagarakis G,Lazou A,Triposkiadis F,Tsilimingas N




Has Abstract


2012-08-01 00:00:00














  • Coronary Computed Tomographic Angiography in the Evaluation of Liver Transplant Candidates.

    abstract::The feasibility, safety, and value of coronary computed tomographic angiography (CCTA) in evaluating orthotopic liver transplant (OLT) candidates are unknown. We studied a cohort of consecutive OLT candidates with intermediate-to-high risk of coronary artery disease (CAD). Intermediate risk candidates received CCTA, a...


    pub_type: 杂志文章


    authors: Poulin MF,Chan EY,Doukky R

    更新日期:2015-10-01 00:00:00

  • Prognostic improvement by multidisciplinary therapy in patients with critical limb ischemia.

    abstract::Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this stu...


    pub_type: 杂志文章


    authors: Hioki H,Miyashita Y,Miura T,Ebisawa S,Motoki H,Izawa A,Tomita T,Koyama J,Ikeda U

    更新日期:2015-02-01 00:00:00

  • Main systolic blood flow patterns in the left and right ventricular outflow tracts determined by Doppler echocardiography.

    abstract::The main blood flow velocity patterns in the LVOT and RVOT were recorded by pulsed Doppler echocardiography in 28 normal healthy cases, in two athletes, and in 85 patients with atrial septal defects, pulmonary regurgitation, tetralogy of Fallot, aortic regurgitation, mitral stenosis, aortic stenosis, mitral regurgitat...


    pub_type: 杂志文章


    authors: Itoh K

    更新日期:1985-03-01 00:00:00

  • Resistance training effects on arterial compliance in premenopausal women.

    abstract:UNLABELLED:Endurance training has been shown to increase arterial compliance; however, the effect of resistance training is unclear. PURPOSE:The purpose of this study was to examine the effect lower body resistance training on arterial compliance in healthy premenopausal women. METHODS:Thirty-two women were assigned ...


    pub_type: 杂志文章,随机对照试验


    authors: Fjeldstad AS,Bemben MG,Bemben DA

    更新日期:2009-12-01 00:00:00

  • Serum zinc concentration in acute myocardial infaction.

    abstract::The serum zinc concentration was examined in 61 patients with acute myocardial infarction who were admitted within twenty-four hours after the onset. Forty-two of 61 patients were admitted within twelve hours. The zinc level fell sharply as early as within three hours after the onset. The minimum values were attained ...


    pub_type: 杂志文章


    authors: Katayama T,Honda Y,Yamasaki H,Kitamura S,Okano Y

    更新日期:1990-06-01 00:00:00

  • Consequence of diseases in aorta on evaluation of aortic regurgitation by aortic flow velocity profiles.

    abstract::The aim of the study was to investigate whether flow velocity profiles of the aorta are related to the severity of aortic valve regurgitation (AR) in patients with diseases of the aorta. Aortic root angiography, abdominal aortic flow velocity measurements by pulsed Doppler method, and regurgitant jet measurements by c...


    pub_type: 杂志文章


    authors: Mitani M,Tamai J,Miyatake K

    更新日期:1994-07-01 00:00:00

  • Differentiating the infarct-related artery on initial electrocardiogram in single or multi-vessel disease in acute inferior myocardial infarction and evaluating involvement of vessels using correspondence analysis.

    abstract::Initial electrocardiography changes were compared prospectively with the findings of coronary angiography to predict the infarct-related artery (IRA) in cases of single- and multi-vessel disease and to demonstrate the relationship between other coexisting coronary involvements and IRA in patients who presented with ac...


    pub_type: 杂志文章


    authors: Kürüm T,Birsin A,Ozbay G,Türe M

    更新日期:2005-07-01 00:00:00

  • Paraumbilical vein aneurysm. Case reports.

    abstract::Two cases of paraumbilical vein aneurysm are reported. The patients were diagnosed as having cirrhotic liver with portal hypertension. Angiography and contrast-enhanced computed tomography demonstrated a dilated paraumbilical vein arising from the left branch of the portal vein. Furthermore, localized dilatation of a ...


    pub_type: 杂志文章


    authors: Ohhira M,Matsumoto A,Ohhira M,Murazumi K,Ohta H,Ono M,Kohgo Y

    更新日期:1996-05-01 00:00:00

  • Pacemaker catheter-induced systolic murmur.

    abstract::Extracardiac sounds secondary to cardiac pacing are well known, but the murmurs originating in the heart after pacemaker insertion are rare. A patient who developed musical systolic murmur following temporary transvenous endocardial pacemaker insertion is described. It is concluded that the murmur was produced by vibr...


    pub_type: 杂志文章


    authors: Gupta SC,Taguchi JT

    更新日期:1982-04-01 00:00:00

  • Early exercise test in acute myocardial infarction treated with intravenous streptokinase.

    abstract::The aim of this study was to assess the value of the early exercise test (ET) in patients with acute myocardial infarction (AMI) treated with IV streptokinase (SK). The authors studied 70 patients with first AMI; 31 were treated with SK and 39 were not. Before discharge everyone was given early exercise up to 5-6 METs...


    pub_type: 杂志文章


    authors: Hamouratidis N,Katsaliakis N,Manoudis F,Lazaridis K,Tselegaridis T,Stravelas V,Simeonidou E,Roussis S

    更新日期:1991-09-01 00:00:00

  • Coronary arteriographic findings during early hours of acute myocardial infarction: response to intracoronary injection of nitrates.

    abstract::We performed coronary arteriography and gave intracoronary injection of nitrates within 8 hours after the onset of symptoms of acute myocardial infarction in eighteen patients. Improved distal filling or patency of the total occluded coronary artery after intracoronary injection of nitrates occurred in 4 of 18 patient...


    pub_type: 杂志文章


    authors: Omote S,Yasue H,Takizawa A,Nagao M,Hyon H,Nishida S,Horie M

    更新日期:1983-08-01 00:00:00

  • Hypereosinophilic syndrome associated with heterozygous factor V gene mutation: an unusual combination resulting in an acute coronary syndrome and recurrent cerebral stroke-a case report.

    abstract::The authors report the first case of a patient with a hypereosinophilic syndrome associated with heterozygous factor V gene mutation, resulting in an acute coronary syndrome and recurrent cerebral stroke despite effective anticoagulation. A 40-year-old man presented with an acute coronary syndrome accompanied by a bra...


    pub_type: 杂志文章


    authors: Engelmann MG,Kolbe T,Faul C,Steinbeck G

    更新日期:2004-03-01 00:00:00

  • Mechanism of rethrombosis after thrombolytic therapy: angioscopic findings and investigation of the coagulation system in dogs.

    abstract::The purpose of this study was to angioscopically observe the process of thrombolysis after intracoronary administration of thrombolytic agents and to investigate the effects of these agents on coagulation/fibrinolysis systems in dogs. The coronary endothelium was removed and thrombus formation was confirmed by angiosc...


    pub_type: 杂志文章


    authors: Maki A,Shirato C,Ohguchi M,Aoki N,Ochiai N,Taguchi S,Aoki I,Ishikawa K

    更新日期:1998-06-01 00:00:00

  • The effect of Valsalva maneuver on P wave in 12-lead surface electrocardiography in patients with paroxysmal atrial fibrillation.

    abstract::The previous studies relating to the effect of the Valsalva maneuver on P wave do not provide detailed information. In those studies, the parameters related to P wave duration during the release phase of the Valsalva maneuver were evaluated. The authors evaluated P wave amplitude as well as P wave duration during the ...


    pub_type: 杂志文章


    authors: Altunkeser BB,Ozdemir K,Gök H,Yazici M,Içli A

    更新日期:2002-07-01 00:00:00

  • Identification of viable myocardium in patients with chronic coronary artery disease and myocardial dysfunction: comparison of low-dose dobutamine stress echocardiography and echocardiography during glucose-insulin-potassium infusion.

    abstract::Low-dose dobutamine stress echocardiography (LDDSE) is one of the methods most used to assess myocardial viability. Glucose-insulin-potassium (GIK) has been shown to increase contraction of the ischemic zone. The aim of this study was to compare LDDSE and echocardiography during GIK infusion for detection of myocardia...


    pub_type: 杂志文章


    authors: Yetkin E,Senen K,Ileri M,Atak R,Battaoglu B,Yetkin O,Tandogan I,Turhan H,Cehreli S

    更新日期:2002-11-01 00:00:00

  • Do vasospasms provoke ocular diseases?

    abstract::Vasospasms in the eye are often combined with digital vasospasms, as can be diagnosed with a nailfold capillaroscopic local cooling test. In 16 patients with a history of cold hands and feet the presence of peripheral vasospasms without any underlying disease was demonstrated by means of nailfold video-capillaroscopy....


    pub_type: 杂志文章


    authors: Gasser P,Flammer J,Guthauser U,Mahler F

    更新日期:1990-03-01 00:00:00

  • Effect of the Kallikrein Inhibitor Aprotinin on Myocardial Ischemia and Necrosis in Man.

    abstract::The effect of administration of aprotinin, a serine esterase inhibitor capable of inactivating kallikrein, on the extent and severity of acute myocardial ischemic injury and subsequent necrosis, was studied in 25 patients. Another group of 25 patients who did not receive aprotinin served as a control group.We administ...


    pub_type: 杂志文章


    authors: Ceceña-Seldner FA,Villarreal J

    更新日期:1980-07-01 00:00:00

  • Anticoagulant-induced shoulder hematoma producing brachial plexus neuropathy--case reports.

    abstract::Hemorrhagic complications from anticoagulants are common and may manifest in any part of the human body. Skin discoloration, pain, tenderness, and soft-tissue swelling may be the main clinical features. The authors present 3 extraordinary cases of brachial plexus neuropathy associated with anticoagulant-induced hemorr...


    pub_type: 杂志文章


    authors: Frangides C,Kounis NG

    更新日期:1992-08-01 00:00:00

  • Possible role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand as markers of plaque instability in coronary artery disease.

    abstract:UNLABELLED:Osteoprotegerin (OPG) produced by cardiovascular system raising the possibility that alterations of OPG serum levels may be associated with coronary artery disease (CAD). Our aim is to assess the possible role of serum OPG and soluble tumor necrosis factor-related apoptosis-inducing ligand (s-TRAIL) in the p...


    pub_type: 杂志文章


    authors: Shaker OG,El-Shehaby A,Nabih M

    更新日期:2010-11-01 00:00:00

  • The significance of Chlamydia pneumoniae in symptomatic carotid stenosis.

    abstract::An association between symptomatic carotid stenosis and recent infection with Chlamydia pneumoniae is reported. Thirty-five patients (20 symptomatic and 15 asymptomatic) with carotid stenosis of 70% to 90% underwent carotid endarterectomy. Endarterectomy was performed without patch and shunt; the average occlusion tim...


    pub_type: 杂志文章


    authors: Katsenis C,Kouskouni E,Kolokotronis L,Rizos D,Dimakakos P

    更新日期:2001-09-01 00:00:00

  • Nonselective left internal mammary artery angiography during right transradial coronary angiography: a simple, rapid, and safe technique.

    abstract::Internal mammary artery angiography is increasingly required, but the technique for left internal mammary artery (LIMA) angiography during right transradial coronary angiography is not well established. The authors investigated the feasibility and safety of a new, simple, and rapid nonselective technique. Following ri...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Cha KS,Kim MH,Hung JS,Woo JS,Kim YD,Kim JS

    更新日期:2001-11-01 00:00:00

  • Methodological issues in the quantitative assessment of quality of life.

    abstract::The term quality of life can be identified in Aristotle's classical writings of 330 BC. In his Nichomachian ethics he recognises the multiple relationships between happiness, well-being, "eudemonia" and quality of life. Historically the concept of quality of life has undergone various interpretations. It involves pers...


    pub_type: 社论


    authors: Panagiotakos DB,Yfantopoulos JN

    更新日期:2011-10-01 00:00:00

  • Prevalence of ventricular premature complexes in healthy and untreated hypertensive elderly people.

    abstract::Twenty-four-hour ambulatory electrocardiographic examination was performed in 130 elderly patients (49 healthy, active subjects; 40 hypertensive without left ventricular hypertrophy; and 41 hypertensive with left ventricular hypertrophy). In the study group, mean age was 72.4 +/- 7.1 (sixty-five to eighty-eight) years...


    pub_type: 杂志文章


    authors: Komsuoğlu B,Duman E,Komsuoğlu SS,Görçin B

    更新日期:1993-06-01 00:00:00

  • Four-barrel aortic dissection involving the ascending aorta. A case report.

    abstract::A fifty-four-year-old woman was evaluated at the authors' hospital for symptoms of repeated chest and back pain. The symptoms had recurred for five months prior to admission. A dynamic computed tomographic scan was performed on admission and demonstrated an enlarged ascending aorta with four barrels secondary to split...


    pub_type: 杂志文章


    authors: Ohte N,Takase R,Hashimoto T,Suzuki K,Narita H,Fujinami T

    更新日期:1995-11-01 00:00:00

  • Differences in vascular reactivity between men and women.

    abstract::The purpose of this study was to compare the gender and age-related differences in vascular reactivity in healthy men and women across a wide age range. Fifty-seven men and 61 women between 20 and 89 years of age, free of cardiovascular disease and risk factors, were categorized into younger (20-39 years), middle-aged...


    pub_type: 杂志文章


    authors: Schank BJ,Acree LS,Longfors J,Gardner AW

    更新日期:2006-12-01 00:00:00

  • Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study.

    abstract::The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 ...


    pub_type: 杂志文章,多中心研究


    authors: Tyrovolas S,Polychronopoulos E,Mariolis A,Piscopo S,Valacchi G,Makri K,Zeimbekis A,Tyrovola D,Bountziouka V,Gotsis E,Metallinos G,Tur JA,Matalas A,Lionis C,Haro JM,Panagiotakos DB

    更新日期:2017-02-01 00:00:00

  • Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland.

    abstract::The aim of this population research was to find out the risk of arterial disease (defined as angina pectoris, myocardial infarction, peripheral occlusive arterial disease, and cerebrovascular disease) and hypertension in persons with varicose veins. A 5-year follow-up study was conducted in Tampere, Finland. A validat...


    pub_type: 杂志文章


    authors: Mäkivaara LA,Ahti TM,Luukkaala T,Hakama M,Laurikka JO

    更新日期:2007-12-01 00:00:00

  • Diagnosis and management of subclavian vein thrombosis: three case reports and review of literature.

    abstract::Axillosubclavian vein thrombosis is seen relatively infrequently in clinical practice when compared with lower limb deep-venous thrombosis; however, it is a condition that can result in significant morbidity if managed suboptimally. A multimodal treatment approach has been increasingly adopted with thrombolysis and/or...


    pub_type: 杂志文章,评审


    authors: Smith RA,Dimitri SK

    更新日期:2008-02-01 00:00:00

  • Is color-flow duplex a good diagnostic test for detection of isolated calf vein thrombosis in high-risk patients?

    abstract::Color-flow duplex scanning (CDS) is a good diagnostic test for lower extremity proximal deep vein thrombosis (DVT). This report aims to evaluate the diagnostic accuracy of CDS in detecting isolated calf DVT in two in-hospital populations. A total of 166 patients had routine DVT testing with both CDS and venography: 99...


    pub_type: 杂志文章


    authors: Eskandari MK,Sugimoto H,Richardson T,Webster MW,Makaroun MS

    更新日期:2000-09-01 00:00:00

  • Association Between Plasma ADAMTS-9 Levels and Severity of Coronary Artery Disease.

    abstract::Genome-wide association studies have shown that a disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS-9) is associated with the development of atherosclerosis. We assessed the level of ADAMTS-9 in patients with coronary artery disease (CAD) and its severity and prognosis. We selected 666 participant...


    pub_type: 杂志文章


    authors: Wei M,Pan H,Guo K

    更新日期:2020-12-14 00:00:00