Antihypertriglyceridemic effect of walnut oil.

Abstract:

:Hyperlipidemia is an important modifiable risk factor of coronary heart diseases. So far, several studies, have indicated the beneficial effects of nuts on plasma lipid profile. Previously, in a pilot study the authors have shown that administration of 20 g/day of Persian walnut (Juglans regia L.) for 8 weeks could decrease plasma triglyceride (TG) concentration by 17% (p value < 0.05). Walnut also increased the plasma HDL-cholesterol level markedly (p value < 0.05). To make the measurements more reliable and to avoid the unwanted walnut side effects (eg, rash, pruritus), this randomized, double blind case-control study was conducted to evaluate the lipid-lowering effect of Persian walnut oil in the population of southern Iran. Sixty hyperlipidemic subjects were randomized into 2 groups; group A patients (n = 29) received walnut oil encapsulated in 500 mg capsules, 3 g/day, for 45 days. Group B patients (n = 31) received placebo and served as the control group. Lipid profiles of both groups were checked before; on days 15, 30, and 45 after the beginning; and 15 days after termination of the study. Plasma TG concentrations decreased by 19% to 33% of baseline in group A patients (p value < 0.05). No statistically significant change was observed in other measured parameters. It was concluded that walnut oil is a good antihypertriglyceridemic natural remedy and should be further explored in more detail.

journal_name

Angiology

journal_title

Angiology

authors

Zibaeenezhad MJ,Rezaiezadeh M,Mowla A,Ayatollahi SM,Panjehshahin MR

doi

10.1177/000331970305400404

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

411-4

issue

4

eissn

0003-3197

issn

1940-1574

journal_volume

54

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:1994-09-01 00:00:00

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    journal_title:Angiology

    pub_type: 杂志文章

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    pub_type: 杂志文章,随机对照试验

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    journal_title:Angiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    更新日期:2003-11-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1177/0003319709348296

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    更新日期:2010-02-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1978-01-01 00:00:00

  • Different effects of beta-1-adrenergic blocking agents with ISA or without ISA on peripheral blood flow.

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    journal_title:Angiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000331978703800403

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    更新日期:1987-04-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 历史文章,杂志文章

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    pub_type: 杂志文章

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    pub_type: 杂志文章,评审

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    更新日期:1991-05-01 00:00:00

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    pub_type: 杂志文章,收录出版

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    更新日期:1992-06-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1177/000331978904000413

    authors: Carr ME Jr

    更新日期:1989-04-01 00:00:00

  • Primary stenting of the superior mesenteric artery for treatment of chronic mesenteric ischemia--a case report.

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    pub_type: 杂志文章

    doi:10.1177/000331979905000108

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    更新日期:1999-01-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2017-08-01 00:00:00

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    pub_type: 杂志文章

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