Abstract:
:It seems important to study initial changes in any sort of disease to elucidate its pathologenesis. Arterial atherosclerosis varies in its severity and extent between each artery. By macroscopic and immunocytochemical studies on aortas and coronary arteries of young Japanese people, the following results were obtained. Fatty streaks are more frequently discovered in aortas than in coronary arteries, while coronary arteries tend to disclose a higher frequency of diffuse intimal thickening with more smooth muscle cells and fewer macrophages. But there is not much difference in frequency of fibrous plaques between the two arteries. Lesions of localized elevation appear to have many more macrophages in coronary arteries. There must be significant structural and functional differences in the "normal" state between aortas and coronary arteries, which may suggest that it is necessary to pay attention to the characteristics specific to each artery in studying the pathogenesis of atherosclerosis.
journal_name
Angiologyjournal_title
Angiologyauthors
Nakamura H,Sakurai Idoi
10.1177/000331979204300308subject
Has Abstractpub_date
1992-03-01 00:00:00pages
229-43issue
3 Pt 1eissn
0003-3197issn
1940-1574journal_volume
43pub_type
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