Intimal cell population and location in arteries of Japanese children and youth.

Abstract:

:It seems important to study initial changes in any sort of disease to elucidate its pathologenesis. Arterial atherosclerosis varies in its severity and extent between each artery. By macroscopic and immunocytochemical studies on aortas and coronary arteries of young Japanese people, the following results were obtained. Fatty streaks are more frequently discovered in aortas than in coronary arteries, while coronary arteries tend to disclose a higher frequency of diffuse intimal thickening with more smooth muscle cells and fewer macrophages. But there is not much difference in frequency of fibrous plaques between the two arteries. Lesions of localized elevation appear to have many more macrophages in coronary arteries. There must be significant structural and functional differences in the "normal" state between aortas and coronary arteries, which may suggest that it is necessary to pay attention to the characteristics specific to each artery in studying the pathogenesis of atherosclerosis.

journal_name

Angiology

journal_title

Angiology

authors

Nakamura H,Sakurai I

doi

10.1177/000331979204300308

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

229-43

issue

3 Pt 1

eissn

0003-3197

issn

1940-1574

journal_volume

43

pub_type

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