Abstract:
:The incidence of contrast-induced acute kidney injury (CI-AKI) is rising due to increased use of coronary angiography and percutaneous coronary intervention. Many agents, including statins, have been evaluated in several studies for the prevention of CI-AKI. To date, there have been 14 prospective randomized studies regarding the efficacy of statins on the patient. Most of these studies and 3 recent meta-analyses have concluded that statins should be used for this purpose, even in patients with reduced low-density lipoprotein cholesterol levels. However, there are also conflicting results, most likely due to marked heterogeneity of patient characteristics, dosage and administration patterns of statins, definition of CI-AKI, and different statistical analyses. In conclusion, it is uncertain whether statins should be prescribed to prevent CI-AKI in the absence of other indications.
journal_name
Angiologyjournal_title
Angiologyauthors
Akyuz S,Yaylak B,Altay S,Kasikcioglu H,Cam Ndoi
10.1177/0003319714549556subject
Has Abstractpub_date
2015-09-01 00:00:00pages
701-7issue
8eissn
0003-3197issn
1940-1574pii
0003319714549556journal_volume
66pub_type
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