Abstract:
:A severe thrombotic thrombocytopenic status, induced by heparin in a sixty-nine-year-old woman undergoing total hip joint arthroplasty, was treated by switching the anticoagulant therapy to coumarin, which induced skin necrosis. There appeared to be a possible causal relation between the severe immune reaction to heparin and the condition that predisposed to skin necrosis in the presence of coumarin. In patients who express a strong immune response to heparin, a different anticoagulant approach other than use of coumarin congeners appears to be justified.
journal_name
Angiologyjournal_title
Angiologyauthors
Shahak A,Pósán E,Szücs G,Rigó J,Boda Zdoi
10.1177/000331979604700715subject
Has Abstractpub_date
1996-07-01 00:00:00pages
725-7issue
7eissn
0003-3197issn
1940-1574journal_volume
47pub_type
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