Cardiac amyloidosis presenting as microvascular angina--a case report.

Abstract:

:Cardiac amyloidosis usually presents with heart failure, but rarely leads to coronary insufficiency. The authors report a case of a 69-year-old Japanese woman with cardiac amyloidosis presenting as microvascular angina. She had exertional angina with positive exercise test and normal coronary angiograms. However, heart failure developed, and she died 3 years after symptom onset. On autopsy, coronary arteries were patent. In contrast to that of the epicardial coronary arteries, histologic examination of the heart revealed severe obstructive alterations of the intramural coronary arteries with amyloid. Furthermore, amyloid was present mainly in the endocardium and the intramural coronary arteries, but there was little present in the myocardium. This case was a rare AL amyloidosis. There have been only 4 reported cases of cardiac amyloidosis that presented with exertional angina, a positive exercise test, and normal coronary angiograms and histologic examination.

journal_name

Angiology

journal_title

Angiology

authors

Ogawa H,Mizuno Y,Ohkawara S,Tsujita K,Ando Y,Yoshinaga M,Yasue H

doi

10.1177/000331970105200407

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

273-8

issue

4

eissn

0003-3197

issn

1940-1574

journal_volume

52

pub_type

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