Placebo-controlled, double-blind trial of hemodilution in peripheral occlusive arterial disease.

Abstract:

:A number of uncontrolled trials has suggested that hemodilution is effective in peripheral occlusive arterial disease. This study was aimed at proving or disproving the efficacy of hemodilution by using a randomized, placebo-controlled, double-blind crossover design. Twenty-four stable claudicants with long, collateralized femoropopliteal obstructions were treated with isovolemic hemodilution with 500 mL of 10% hydroxyethyl starch 200 and sham dilutions. Three weeks of hemodilution lowered blood and plasma viscosity, as well as hematocrit, and increased resting blood flow and pain-free walking distance. Placebo treatments produced no such favorable changes. It is concluded that hemodilution therapy can be clinically effective in patients with arterial obstructions in the lower extremities. Hemodilution seems particularly promising under hemodynamic condition of low shear stresses in vivo.

journal_name

Angiology

journal_title

Angiology

authors

Ernst E,Matrai A,Kollar L

doi

10.1177/000331978904000509

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

479-83

issue

5

eissn

0003-3197

issn

1940-1574

journal_volume

40

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::Platelet-derived growth factor (PDGF) and beta-thromboglobulin (beta-TG) are released from alpha granules during platelet activation. PDGF may play a role in the development of atherosclerosis and the late restenosis after percutaneous transluminal coronary angioplasty (PTCA). The effect of acetylsalicylic acid (ASA) ...

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    doi:10.1177/000331979304400807

    authors: Vissinger H,Husted SE,Kristensen SD,Nielsen HK

    更新日期:1993-08-01 00:00:00

  • Pacemaker catheter-induced systolic murmur.

    abstract::Extracardiac sounds secondary to cardiac pacing are well known, but the murmurs originating in the heart after pacemaker insertion are rare. A patient who developed musical systolic murmur following temporary transvenous endocardial pacemaker insertion is described. It is concluded that the murmur was produced by vibr...

    journal_title:Angiology

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    doi:10.1177/000331978203300408

    authors: Gupta SC,Taguchi JT

    更新日期:1982-04-01 00:00:00

  • An unusual increase of blood anti-beta 2-glycoprotein-I antibody but not antiphospholipid antibody in cerebral ischemia--a case report.

    abstract::An abnormal increase in anti-beta2-glycoprotein I antibodies (abeta2GPI) is capable of producing thrombosis and the vasculopathy-simulating antiphospholipid antibody (aPL). However, it is rarely described in cerebral ischemia without an association with aPL. The authors report a middle-aged man who experienced recurre...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331970105200211

    authors: Chen WH,Liu JS

    更新日期:2001-02-01 00:00:00

  • Gastrointestinal complications after open heart surgery: incidence and determinants of risk factors.

    abstract::Acute mesenteric ischemia is a rare but serious complication of open heart surgery. Between January 2009 and January 2012, 1360 adult patients underwent open heart surgery with cardiopulmonary bypass at our institution; 29 patients presented gastrointestinal complications. Eight patients developed acute mesenteric isc...

    journal_title:Angiology

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    doi:10.1177/0003319713482357

    authors: Sever K,Ozbek C,Goktas B,Bas S,Ugurlucan M,Mansuroglu D

    更新日期:2014-05-01 00:00:00

  • Left ventricular systolic and diastolic function in normotensive type 2 diabetic patients with or without autonomic neuropathy: a radionuclide ventriculography study.

    abstract::We investigated the relation between diabetic autonomic neuropathy (DAN) and left ventricular (LV) function in 59 patients with type 2 diabetes mellitus (T2DM) free of coronary artery disease (CAD) or hypertension. Diabetic autonomic neuropathy was established by ≥2 abnormal autonomic nervous function tests. Left vent...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319713510966

    authors: Didangelos TP,Arsos G,Karamitsos T,Iliadis F,Papageorgiou A,Moralidis E,Athyros V

    更新日期:2014-11-01 00:00:00

  • Assessment of collateral perfusion: a pharmacodynamic study with buflomedil hydrochloride.

    abstract::The aim of the study was to assess the influence of Buflomedil hydrochloride on collateral function. Ten patients with isolated superficial femoral occlusions were investigated twice by duplex sonography with measurement sites at the common femoral artery (CF) and the popliteal artery (PA). After the second scan 200 m...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970005100405

    authors: Labs KH,Eichlisberger R,Jeanneret C,Frauchiger B,Aschwanden M,Jäger KA

    更新日期:2000-04-01 00:00:00

  • Left Bundle Branch Block in Acute Cardiac Events: Insights From a 23-Year Registry.

    abstract::Between 1991 and 2013, we evaluated the demographics, presentations, and final diagnosis of patients hospitalized with acute cardiac events and left bundle branch block (LBBB). Of 50 992 patients, 768 (1.5%) had LBBB. Compared with non-LBBB patients, patients with LBBB were mostly older, female, diabetic, and had hype...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319714560223

    authors: Alkindi F,El-Menyar A,Al-Suwaidi J,Patel A,Gehani AA,Singh R,Albinali H,Arabi A

    更新日期:2015-10-01 00:00:00

  • Echocardiographic epicardial adipose tissue predicts subclinical atherosclerosis: epicardial adipose tissue and atherosclerosis.

    abstract::We examined the relationship between coronary flow rate and epicardial adipose tissue (EAT) in patients with slow coronary flow (SCF) and normal coronary arteries. The study included 40 consecutive patients with stable angina pectoris who had normal coronary arteries. All patients underwent echocardiography. To determ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319711432452

    authors: Comert N,Yucel O,Ege MR,Yaylak B,Erdogan G,Yilmaz MB

    更新日期:2012-11-01 00:00:00

  • Nonselective left internal mammary artery angiography during right transradial coronary angiography: a simple, rapid, and safe technique.

    abstract::Internal mammary artery angiography is increasingly required, but the technique for left internal mammary artery (LIMA) angiography during right transradial coronary angiography is not well established. The authors investigated the feasibility and safety of a new, simple, and rapid nonselective technique. Following ri...

    journal_title:Angiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000331970105201107

    authors: Cha KS,Kim MH,Hung JS,Woo JS,Kim YD,Kim JS

    更新日期:2001-11-01 00:00:00

  • Right coronary arteriocameral fistula into the right ventricle. An inspiratory accentuation of continuous murmur: a case report.

    abstract::A case of a right coronary artery fistula into the right ventricle is presented. The clinical diagnosis was based on the presence of a continuous murmur best heard in the epigastrium, which increased in intensity and duration on inspiration . This report stresses the importance of this sign in the localization of the ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977903000310

    authors: Munsi SC,Dalal JJ,Nair KG

    更新日期:1979-03-01 00:00:00

  • Serum uric acid concentration and asymptomatic hyperuricemia with subclinical organ damage in general population.

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    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319713513143

    authors: Li Y,Lu J,Wu X,Yang C

    更新日期:2014-08-01 00:00:00

  • Transcutaneous electrical nerve stimulation in the symptomatic management of thrombophlebitis.

    abstract::Transcutaneous electrical nerve stimulation (TENS) afforded significant relief of the pain associated with acute and recurrent thrombophlebitis in 90% of 39 patients so treated. The method is simple to administer, noninvasive, and apparently free of side effects. It can be self-administered by the patient after approp...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977903000404

    authors: Roberts HJ

    更新日期:1979-04-01 00:00:00

  • Renin responses in patients with orthostatic hypotension: case reports.

    abstract::In orthostatic hypotensive patients renin is reported to increase in response to head-up tilt unless the lesion involves postganglionic sympathetic efferent nerves. The authors examined responses of plasma renin activity (PRA) to acute blood pressure reduction in 4 patients with orthostatic hypotension. When the coexi...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:

    authors: Asato C,Muratani H,Touma T,Kawazoe N,Kimura Y,Takishita S,Fukiyama K

    更新日期:1993-07-01 00:00:00

  • Blood rheology after LDL apheresis using dextran sulfate cellulose absorption--a case report.

    abstract::The authors describe a thirty-eight-year-old woman with familial hypercholesterolemia treated by dextran sulfate cellulose adsorption apheresis. This technique and the selective extracorporeal LDL cholesterol elimination by immunoabsorption or heparin-induced precipitation not only dramatically decrease blood lipids b...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979204300710

    authors: Koenig W,Ditschuneit HH,Hehr R,Grunewald RW,Ernst E,Hombach V

    更新日期:1992-07-01 00:00:00

  • Association between physical activity and endogenous fibrinolysis in peripheral arterial disease: a cross-sectional study.

    abstract::The purpose of this study was to determine whether daily physical activity was independently related to endogenous fibrinolysis in subjects with peripheral arterial disease (PAD). One hundred and six subjects with peripheral arterial disease (PAD) and intermittent claudication were characterized on the activity level ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970205300401

    authors: Gardner AW,Killewich LA

    更新日期:2002-07-01 00:00:00

  • Coronary artery calcification progression in asymptomatic individuals with initial score of zero.

    abstract::The aim of this study is to determine the progression of coronary artery calcification (CAC) using electron beam computed tomography (CT) when the initial CAC score (CACS) is zero and to determine the best interval to repeat a CAC scan. We studied 388 individuals with zero CACS (308 males; mean age: 48.8 ± 8.26 years)...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319712459213

    authors: Koulaouzidis G,Charisopoulou D,Maffrett S,Tighe M,Jenkins PJ,McArthur T

    更新日期:2013-10-01 00:00:00

  • Errors of computer electrocardiography.

    abstract::A review of 6938 computer-generated electrocardiogram interpretations was undertaken by a single cardiologist. The computer-assisted program correctly interpreted 51.6% of the tracings. One or more corrections were necessary in 48.4%. The greatest number of incorrect interpretations involved repolarization (T wave) ab...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704801204

    authors: RuDusky BM

    更新日期:1997-12-01 00:00:00

  • Buerger's disease in women. A case report with critical approach to the literature.

    abstract::The Authors describe a case of arteritis of the lower limbs in a woman, in which the clinico-angiographical features were suggestive for Buerger's disease, and this was confirmed by histological examination of the left posterior tibial artery. A bilateral lumbar sympathectomy was effective at least in slowing the cour...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978503600308

    authors: Cavallaro A,Meloni F,Sciacca V,Transi MG,DiGiacomo V

    更新日期:1985-03-01 00:00:00

  • Delineation of premature P waves on four-dimensional electrocardiography, a new display of electrical forces by computer techniques.

    abstract::This study investigated the feasibility of four-dimensional electrocardiography (4-D ECG), a new display in which the vector loop was rotated and scanned along a timed axis to overcome the shortcomings of vectorcardiography (VCG). The subjects consisted of 38 patients with premature atrial complexes and 30 controls. T...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979604701111

    authors: Morikawa J,Habuchi Y,Nishio M,Yamamoto T,Tanaka H,Kashima K

    更新日期:1996-11-01 00:00:00

  • Association Between the Visceral Adiposity Index and Homeostatic Model Assessment of Insulin Resistance in Participants With Normal Waist Circumference.

    abstract::We assessed the correlation between the visceral adiposity index (VAI; a useful indicator of adipose distribution and function) and homeostatic model assessment of insulin resistance (HOMA-IR) in participants with normal waist circumference. A cross-sectional study was conducted, which included 1834 Chinese adults. Th...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319716682120

    authors: Ji B,Qu H,Wang H,Wei H,Deng H

    更新日期:2017-09-01 00:00:00

  • Cardiovascular disease and high-mobility group box 1--is a new inflammatory killer in town?

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    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/0003319712458032

    authors: Cirillo P,Giallauria F,Di Palma V,Maresca F,Ziviello F,Bevilacqua M,Vigorito C,Trimarco B

    更新日期:2013-07-01 00:00:00

  • Slightly elevated high-sensitivity C-reactive protein (hsCRP) concentrations are associated with carotid atherosclerosis in women with varying degrees of glucose tolerance.

    abstract::We examined whether high-sensitivity C-reactive protein (hsCRP) ≥2.0 mg/L was associated with increased intima-media thickness (IMT), plaque burden, and plaque echolucency in carotid arteries. Women (n = 635) from a population sample of 64-year-old females with varying degrees of glucose tolerance underwent risk facto...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319710370959

    authors: Prahl U,Wikstrand J,Bergström GM,Behre CJ,Hulthe J,Fagerberg B

    更新日期:2010-11-01 00:00:00

  • Effect of pindolol and propranolol on sinus node recovery time and atrioventricular conduction intervals.

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    journal_title:Angiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000331978703800601

    authors: Kostis JB,Binenbaum SZ,Oliveri P,Sclar C,Hosler M

    更新日期:1987-06-01 00:00:00

  • Effects of antiarrhythmic agents on cardiac function.

    abstract::Many, if not most antiarrhythmic drugs, even with differing pharmacologic properties, are capable of myocardial depression. That this has not occurred commonly with most drugs currently available may reflect several factors. These may include depression of myocardial function which is not clinically overt or which is ...

    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331978203300403

    authors: Gottdiener JS,DiBianco R,Fletcher RD

    更新日期:1982-04-01 00:00:00

  • Calf blood flow and systolic blood pressure in patients with hyperviscosity of the blood.

    abstract::The calf blood flow and the ankle blood pressure at rest and during post-ischemic reactive hyperemia were measured by an airfilled rubber segment plethysmograph in 5 patients with hyperviscosity of the blood. The patients had no signs of peripheral arterial disease. A normal flow and pressure pattern was obtained. It ...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331977903000504

    authors: Valnes K,Lorentsen E,Holter B

    更新日期:1979-05-01 00:00:00

  • Central inhibition of sympathetic overdrive by clonidine in acute myocardial infarction with systolic hypertension. Haemodynamic study.

    abstract::Intravenous clonidine was used to treat systolic hypertension (systolic blood pressure greater than 160 mm Hg) in 15 patients with acute myocardial infarction and documented sympathetic overactivity (high plasma norepinephrine). Its effects on haemodynamics and blood gases were studied. After one hour, clonidine signi...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331978603700903

    authors: Renard M,Liebens I,Waterschoot P,Bernard R

    更新日期:1986-09-01 00:00:00

  • Successful treatment of intermittent claudication due to spinal canal stenosis using beraprost sodium, a stable prostaglandin I2 analogue. A case report.

    abstract::The syndrome of intermittent claudication can be induced not only by vascular insufficiency of the lower limbs but also by diseases of the spinal cord and cauda equina. The authors describe a sixty-year-old man with intermittent claudication due to spinal canal stenosis who was successfully treated with beraprost sodi...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331979704800510

    authors: Kato H,Emura S,Ngashima K,Kishikawa H,Takashima T,Ohmori K

    更新日期:1997-05-01 00:00:00

  • Young woman's digestive arterial occlusion--a case report and literature review.

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    journal_title:Angiology

    pub_type: 杂志文章,评审

    doi:10.1177/000331979804901109

    authors: Crètel E,Disdier P,Chagnaud C,Tournigand P,Harlé JR,Piette JC,Weiller PJ

    更新日期:1998-11-01 00:00:00

  • Identification of viable myocardium in patients with chronic coronary artery disease and myocardial dysfunction: comparison of low-dose dobutamine stress echocardiography and echocardiography during glucose-insulin-potassium infusion.

    abstract::Low-dose dobutamine stress echocardiography (LDDSE) is one of the methods most used to assess myocardial viability. Glucose-insulin-potassium (GIK) has been shown to increase contraction of the ischemic zone. The aim of this study was to compare LDDSE and echocardiography during GIK infusion for detection of myocardia...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/000331970205300607

    authors: Yetkin E,Senen K,Ileri M,Atak R,Battaoglu B,Yetkin O,Tandogan I,Turhan H,Cehreli S

    更新日期:2002-11-01 00:00:00

  • Relationship of Endothelial Cell-Specific Molecule 1 Level in Stress Hyperglycemia Patients With Acute ST-Segment Elevation Myocardial Infarction: A Pilot Study.

    abstract::Endothelial cell-specific molecule 1 ([ESM-1], endocan) is a new biomarker of endothelial dysfunction, which may be involved in the pathogenesis of atherosclerosis and stress hyperglycemia in patients with acute ST-segment elevation myocardial infarction (STEMI). Therefore, we investigated serum ESM-1 levels in patien...

    journal_title:Angiology

    pub_type: 杂志文章

    doi:10.1177/0003319715621996

    authors: Qiu C,Sui J,Zhang Q,Wei P,Wang P,Fu Q

    更新日期:2016-10-01 00:00:00