Morphologic changes in pulmonary vasculature with arteriographic correlation.

Abstract:

:During fetal life the pulmonary circulation is one of high resistance. Soon after birth with the onset of breathing and thereafter, sequential structural changes in pulmonary vasculature take place. Several authors have reported differently on this structural remodeling. This study describes the changes in the pulmonary vasculature occurring following birth. Twenty-five cases submitted to autopsy with ages ranging from newborns up to fourteen years were studied. Postmortem arteriography was undertaken in most of the cases and arterial morphology was quantitated by histomorphometry. It was found that the thick-walled pulmonary arteries of the newborn show a reduction in medial thickness over a period of one month, the reduction being most rapid in the first three days. After one month there is no significant change in medial thickness until fourteen years of age.

journal_name

Angiology

journal_title

Angiology

authors

Basu S,Datta BN,Khandelwal N

doi

10.1177/000331979604700408

subject

Has Abstract

pub_date

1996-04-01 00:00:00

pages

375-80

issue

4

eissn

0003-3197

issn

1940-1574

journal_volume

47

pub_type

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