Abstract:
:Low albumin and the albumin-globulin ratio (AGR) were associated with vascular adverse events. Our study explores the AGR as a predictor of mortality after non-ST-segment elevation myocardial infarction (NSTEMI). In an observational study of 570 NSTEMI patients admitted to a tertiary center between 2004 and 2006, patients were stratified into equal tertiles according to AGR. The primary outcome was 4-year all-cause mortality. The 4-year mortality rates in the first, second, and third AGR tertiles were 88 (47%) of 189, 48 (25%)of 190 , and 19 (10%) of 191, respectively (P < .0001). After adjusting for 20 confounding variables, AGR first tertile (AGR <1.12) had a higher mortality versus second tertile (hazard ratio [HR] 2.6, P < .001). Likewise, the AGR second tertile had higher mortality versus the third tertile (AGR ≥1.34; HR 2.3, P = .004). The albumin-globulin ratio is a significant independent predictor of long-term mortality after NSTEMI in patients with normal serum albumin levels. Further studies are needed to explain the underlying mechanisms.
journal_name
Angiologyjournal_title
Angiologyauthors
Azab B,Bibawy J,Harris K,Khoueiry G,Akerman M,Selim J,Khalil S,Bloom S,McGinn JT Jrdoi
10.1177/0003319712436577subject
Has Abstractpub_date
2013-02-01 00:00:00pages
137-45issue
2eissn
0003-3197issn
1940-1574pii
0003319712436577journal_volume
64pub_type
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