Unmodified and phosphorylated prolactin and gamma delta T cell development and function.

abstract：:This study assessed the expression of complement receptor 1 (CR1), decay accelerating factor (DAF) and membrane inhibitor of reactive lysis (CD59) on the erythrocytes and glomerulus of diffuse proliferative glomerulonephritis (DPGN) of systemic lupus erythematosus (SLE) patients using flow cytometry and immunofluoresc...

journal_title：Lupus

authors： Arora M,Arora R,Tiwari SC,Das N,Srivastava LM

更新日期：2000-01-01 00:00:00

abstract：:The purpose of the present study was to evaluate patients with the antiphospholipid syndrome with particular attention to their initial clinical features, final diagnoses and the course of thrombotic events in association with therapy. The methodology applied was the following: retrospective analysis of 30 patient fil...

journal_title：Lupus

authors： Vlachoyiannopoulos PG,Tsiakou E,Chalevelakis G,Raptis SA,Moutsopoulos HM

更新日期：1994-04-01 00:00:00

abstract：:Thrombosis in the presence of persistently positive tests for antiphospholipid antibodies is termed thrombotic antiphospholipid syndrome (APS). At present, 'standard' secondary thromboprophylaxis in thrombotic APS is treatment with moderate intensity oral anticoagulants for life after a first venous thrombosis and wit...

journal_title：Lupus

authors： Derksen RH,de Groot PG

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence of idiopathic intracranial hypertension (IIH) in patients with systemic lupus erythematosus (SLE) and to describe the manifestations, treatments and outcomes in these patients. METHODS:We reviewed the medical records of 1084 patients with SLE followed up from January 1997 to June 2...

journal_title：Lupus

authors： Kim JM,Kwok SK,Ju JH,Kim HY,Park SH

更新日期：2012-04-01 00:00:00

abstract：:Eosinophilic gastroenteritis (EGE) is an uncommon disease and has rarely been reported in association with connective tissue diseases as systemic lupus erythematosus. We report a 36-year-old woman who developed recurrent episodes of abdominal pain, nausea, vomiting and melena. Complete blood counts showed elevated eos...

journal_title：Lupus

authors： Jaimes-Hernandez J,Aranda-Peirera P,Melendez-Mercado CI

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:The feed-forward loop of type I interferons (IFNs) production and subsequent immunopathology of systemic lupus erythematosus (SLE) has been hypothesised to be disrupted with inhibition of IFNα or type I IFN receptor subunit 1 (IFNAR). This systematic review and meta-analysis present the treatment efficacy and...

journal_title：Lupus

authors： Koh JWH,Ng CH,Tay SH

更新日期：2020-12-01 00:00:00

abstract：:Endothelial and/or platelet activation likely initiates thrombus formation. Whether antiphospholipid antibody (aPL) is an activator, a toxic response, or a protective response is not clear, nor is it certain whether aPL is germ-line encoded or antigen-driven. The pregnancy model is particularly informative. Alternativ...

journal_title：Lupus

authors： Lockshin MD

更新日期：1996-10-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) positivity may disappear over time in some SLE patients. Anti-double-stranded DNA (dsDNA) antibody titers and complement levels may vary with time and...

journal_title：Lupus

authors： Ippolito A,Wallace DJ,Gladman D,Fortin PR,Urowitz M,Werth V,Costner M,Gordon C,Alarcón GS,Ramsey-Goldman R,Maddison P,Clarke A,Bernatsky S,Manzi S,Bae SC,Merrill JT,Ginzler E,Hanly JG,Nived O,Sturfelt G,Sanchez-Gu

更新日期：2011-03-01 00:00:00

abstract：:The purpose of study was to determine the nature, outcomes and associated risk factors of invasive fungal infection (IFI) in patients with systemic lupus erythematosus (SLE), and compare the incidence of IFI in patients with rheumatoid arthritis (RA). A total of 1155 patients with SLE and 2004 patients with RA were re...

journal_title：Lupus

authors： Kim HJ,Park YJ,Kim WU,Park SH,Cho CS

更新日期：2009-06-01 00:00:00

abstract：:Patients with chronic hepatitis C virus (HCV) infection frequently present with extrahepatic manifestations covering a large spectrum, involving different organ systems leading to the concept of systemic HCV infection. These manifestations include autoimmune phenomena and frank autoimmune and/or rheumatic diseases and...

journal_title：Lupus

authors： Rosenthal E,Cacoub P

更新日期：2015-04-01 00:00:00

abstract：:Neuropsychiatric manifestations of systemic lupus erythematosus are common and disabling yet their pathogenesis is poorly understood. We investigated the role of cerebrovascular endothelial dysfunction in systemic lupus erythematosus and its neuropsychiatric manifestations. Subjects with systemic lupus erythematosus w...

journal_title：Lupus

authors： Davey R,Bamford J,Emery P

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:The objectives of this paper are to compare sexual function and distress in women with systemic lupus erythematosus (SLE) and in healthy controls; to determine the association between disease characteristics, quality of life, psychopathology and sexual function; and to compare sexual function and distress of ...

journal_title：Lupus

authors： García Morales M,Callejas Rubio JI,Peralta-Ramírez MI,Henares Romero LJ,Ríos Fernández R,Camps García MT,Navarrete Navarrete N,Ortego Centeno N

更新日期：2013-09-01 00:00:00

abstract：:Previous studies in our laboratory showed a dose-dependent and hormone-specific increase in CD154 expression in T cells from females with systemic lupus erythematosus (SLE). This present study investigates if the estrogen-dependent increase in CD154 expression is due to stabilization of the messenger RNA. T cells from...

journal_title：Lupus

authors： Li X,Rider V,Kimler BF,Abdou NI

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:High-mobility group box 1 protein (HMGB-1) has been implicated in the pathogenesis of lupus nephritis (LN). There is increased HMGB-1 expression in the kidneys and increased levels are observed in serum and urine of patients with LN. This study was performed to determine whether the increased urinary HMGB-...

journal_title：Lupus

authors： Jog NR,Blanco I,Lee I,Putterman C,Caricchio R

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore the risk factors for 'severe' neuropsychiatric (NP) flare in patients with systemic lupus erythematosus (SLE). METHODS:This retrospective study comprised newly diagnosed 184 adult SLE patients who visited Hokkaido University Hospital between 2006 and 2017. In this study, severe NP...

journal_title：Lupus

authors： Aso K,Kono M,Kono M,Watanabe T,Shimizu Y,Ogata Y,Fujieda Y,Kato M,Oku K,Amengual O,Yasuda S,Atsumi T

更新日期：2020-09-01 00:00:00

abstract：:The complexity of the therapeutic approach in systemic lupus erythematosus (SLE) is increased by the large number of patients who do not respond to the first-line therapies and by relapses after initial clinical remission. In these patients, second-line drugs are often prescribed according to individual clinical decis...

journal_title：Lupus

authors： Ramos-Casals M,Soto MJ,Cuadrado MJ,Khamashta MA

更新日期：2009-08-01 00:00:00

abstract：:The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) Damage Index (SDI) is an accepted instrument to ascertain damage. It has been shown to vary among different SLE populations. The aim of this study was to assess SDI score, pattern and factors related to damage in Brazilian SL...

journal_title：Lupus

authors： Soares M,Reis L,Papi JA,Cardoso CR

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Systemic lupus erythematosus (SLE) is regarded as a prototype autoimmune disease because it can serve as a means for studying differences between ethnic minorities and sex. Traditionally, all Hispanics have been bracketed within the same ethnic group, but there are differences between Hispanics from Spain an...

journal_title：Lupus

authors： Hernández Cruz B,Alonso F,Calvo Alén J,Pego-Reigosa JM,López-Longo FJ,Galindo-Izquierdo M,Olivé A,Tomero E,Horcada L,Uriarte E,Erausquin C,Sánchez-Atrio A,Montilla C,Santos Soler G,Fernández-Nebro A,Blanco R,Rodríguez-Góm

更新日期：2020-01-01 00:00:00

abstract：:This study was designed to investigate whether Foxp3( +) regulatory T (Treg) cells play a role in the histopathologic changes of primary Sjögren's Syndrome (pSS) and to evaluate other factors possibly associated with Foxp3(+) Treg cells in pSS patients. The number of FoxP3-expressing T cells in peripheral blood (PB) o...

journal_title：Lupus

authors： Sarigul M,Yazisiz V,Bassorgun CI,Ulker M,Avci AB,Erbasan F,Gelen T,Gorczynski RM,Terzioglu E

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The objective of this paper is to evaluate whether the different International Society of Nephrology/Renal Pathology Society (ISN/RPS) classes of proliferative lupus nephritis (LN) have a distinct baseline presentation, short-term response to immunosuppression (IS) and long-term prognosis. METHODS:Ninety-eig...

journal_title：Lupus

authors： Vandepapelière J,Aydin S,Cosyns JP,Depresseux G,Jadoul M,Houssiau FA

更新日期：2014-02-01 00:00:00

abstract：:The objective was to investigate the relation between serum levels of interferon-alpha (IFN-alpha), the activity of an endogenous IFN-alpha inducing factor (SLE-IIF), clinical and immunological disease activity as well as serum levels of antiretroviral antibodies in SLE. Serum levels of IFN-alpha were measured in seri...

journal_title：Lupus

authors： Bengtsson AA,Sturfelt G,Truedsson L,Blomberg J,Alm G,Vallin H,Rönnblom L

更新日期：2000-01-01 00:00:00

abstract：:It is well known that women with systemic lupus erythematosus (SLE) who have antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss. Additionally, other reproductive processes, such as unexplained infertility and implantation failure after in vitro fertilization and embryo transfer may be affected ...

journal_title：Lupus

authors： Balasch J,Cervera R

更新日期：2002-01-01 00:00:00

abstract：:Background While thrombopoeitin (TPO) agonists that act to simulate platelet production have been approved for use in steroid-refractory chronic immune thrombocytopenia purpura (ITP), there are few data on the safety and efficacy of these medications in patients with concurrent systemic lupus erythematosus (SLE) or an...

journal_title：Lupus

authors： Lusa A,Carlson A

更新日期：2018-09-01 00:00:00

abstract：:This work describes the development of sideroblastic anemia (SA) during the clinical activity of systemic lupus erythematosus (SLE) in two patients. The cases refer to two women with SLE who developed SA during a relapse of the illness. Both patients fulfilled at least four criteria of the American Association of Rheu...

journal_title：Lupus

authors： Jiménez-Balderas FJ,Morales-Polanco MR,Gutierrez L

更新日期：1994-06-01 00:00:00

abstract：:Objective The objectives of this paper are to objectively measure habitual physical activity levels in patients with primary Sjögren's syndrome (pSS) with mild disease activity and to determine to which extent it may be associated with physical capacity and function and clinical features. Methods In this cross-section...

journal_title：Lupus

authors： Dassouki T,Benatti FB,Pinto AJ,Roschel H,Lima FR,Augusto K,Pasoto S,Pereira RMR,Gualano B,de Sá Pinto AL

更新日期：2017-06-01 00:00:00

abstract：:Autoantibodies against prothrombin, including lupus anticoagulant antibodies (LAC), have been identified in patients with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). To identify the epitopes of LAC in patients with SLE and APS, we analyzed B cell epitopes of anti-prothrombin Abs. Prothrombi...

journal_title：Lupus

authors： Akimoto T,Akama T,Kono I,Sumida T

更新日期：1999-01-01 00:00:00

abstract：:Chronic intestinal pseudo-obstruction (CIPO) is a rare clinical syndrome of ineffective intestinal motility characterised by clinical and radiological evidence of intestinal obstruction with no identifiable mechanical lesion. CIPO can either be idiopathic or secondary to a systemic disease, like systemic lupus erythem...

journal_title：Lupus

authors： Khairullah S,Jasmin R,Yahya F,Cheah TE,Ng CT,Sockalingam S

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:There is no report about the association between GATA3 rs3824662 polymorphism and systemic lupus erythematosus (SLE). OBJECTIVE:To investigate the possible role of GATA3 rs3824662 polymorphism as a susceptibility risk factor for either adult SLE (aSLE) or pediatric SLE (pSLE) and to evaluate its role in the...

journal_title：Lupus

authors： Mosaad YM,Hammad A,Elghzaly AA,Tawhid ZME,Hammad EM,Showma A,Abdelsalam R,Elmoughy A,Fawzy IM,Anber N

更新日期：2018-11-01 00:00:00

abstract：:The effect of beta 2glycoprotein I (beta 2GPI) and human monoclonal anticardiolipin antibody (aCL) on the protein S/C4b-binding protein (C4BP) system was evaluated. The binding of C4BP to protein S was assessed by ELISA in the presence of beta 2GPI with/without human monoclonal aCL. beta 2GPI downregulated the binding...

journal_title：Lupus

authors： Atsumi T,Khamashta MA,Ames PR,Ichikawa K,Koike T,Hughes GR

更新日期：1997-01-01 00:00:00

abstract：:Lupus nephritis during pregnancy increases morbidity and mortality for mother and baby. Flares are difficult to treat as many therapeutic options are teratogenic or fetotoxic. Steroids alone may be unable to control disease activity and are associated with higher rates of preterm delivery, sepsis and gestational diabe...

journal_title：Lupus

authors： Webster P,Wardle A,Bramham K,Webster L,Nelson-Piercy C,Lightstone L

更新日期：2014-10-01 00:00:00