A combination vaccine confers full protection against co-infections with influenza, herpes simplex and respiratory syncytial viruses.

abstract：BACKGROUND:Worldwide coverage of hepatitis B (HB) vaccination is increasing. This should be considered when determining the best strategy for catch-up HB vaccination in migrant children, who rarely have written proof of past immunizations. This study aimed to estimate HB vaccine protection, chronic HB prevalence and to...

journal_title：Vaccine

authors： Fougère Y,El Houss S,Suris JC,Rouvenaz-Defago S,Miletto D,Von der Weid L,Willen F,Williams-Smith JA,Gehri M,Crisinel PA

更新日期：2018-07-16 00:00:00

abstract：:In future, a policy of "vaccinate-to-live" may be included in the repertoire of foot-and-mouth disease (FMD) control measures and in support of this approach, we have investigated the hypothesis that vaccine-induced reduction in virus replication and excretion from pigs can be correlated to the severity of clinical si...

journal_title：Vaccine

authors： Parida S,Fleming L,Oh Y,Mahapatra M,Hamblin P,Gloster J,Doel C,Gubbins S,Paton DJ

更新日期：2007-11-07 00:00:00

abstract：:In this study, the potential of N-Trimethyl chitosan (TMC, degree of quaternization 50%) and dextran microparticles for pulmonary delivery of diphtheria toxoid (DT) was investigated. The antigen-containing microparticles were prepared by drying of an aqueous solution of polymer and DT through a supercritical fluid (SC...

journal_title：Vaccine

authors： Amidi M,Pellikaan HC,Hirschberg H,de Boer AH,Crommelin DJ,Hennink WE,Kersten G,Jiskoot W

更新日期：2007-09-17 00:00:00

abstract：:In the present study, we investigated the duration of protection afforded to pigs immunized in two different prime-boost regimens: one is homologus priming and boosting with a protein vaccine, and the other is priming with a DNA vaccine and boosting with the protein vaccine. Groups of pigs that received the same vacci...

journal_title：Vaccine

authors： Guo YJ,Sun SH,Zhang Y,Chen ZH,Wang KY,Huang L,Zhang S,Zhang HY,Wang QM,Wu D,Zhu WJ

更新日期：2004-09-28 00:00:00

abstract：:Typhoid vaccination is recommended in the United States before travel to countries where typhoid fever is endemic, though little information is available on its effectiveness in travelers. We estimated typhoid vaccination effectiveness (VE) by comparing vaccination status in cases of typhoid fever and paratyphoid feve...

journal_title：Vaccine

authors： Mahon BE,Newton AE,Mintz ED

更新日期：2014-06-17 00:00:00

abstract：:Recently avian influenza A viruses of the H5N1 subtype were shown to infect humans in the Hong Kong area, resulting in the death of six people. Although these viruses did not efficiently spread amongst humans, these events illustrated that influenza viruses of subtypes not previously detected in humans could be at the...

journal_title：Vaccine

authors： Rimmelzwaan GF,Claas EC,van Amerongen G,de Jong JC,Osterhaus AD

更新日期：1999-03-17 00:00:00

abstract：:Mucin1 (MUC1) is expressed ubiquitously on breast cancer cells and is a potential target for the generation of cytotoxic T cells for vaccination against breast cancer. Thus far studies of the immunogenicity of MUC1 have used peptides from the variable number of tandem repeat (VNTR); mice so immunised can generate stro...

journal_title：Vaccine

authors： Pietersz GA,Li W,Osinski C,Apostolopoulos V,McKenzie IF

更新日期：2000-04-03 00:00:00

abstract：:Understanding the mechanisms of generation and maintenance of immunological memory is crucial for rational vaccine design. A hypothesis known as relay hypothesis was earlier proposed which explains the maintenance of immunological memory through interaction of idiotypic and anti-idiotypic lymphocytes. In the present s...

journal_title：Vaccine

authors： Vani J,Nayak R,Shaila MS

更新日期：2007-06-21 00:00:00

abstract：:Immune responses to poorly immunogenic antigens, such as polysaccharides, can be enhanced by conjugation to carriers. Our previous studies indicate that conjugation to Vi polysaccharide of Salmonella Typhi may also enhance immunogenicity of some protein carriers. We therefore explored the possibility of generating a b...

journal_title：Vaccine

authors： An SJ,Scaria PV,Chen B,Barnafo E,Muratova O,Anderson C,Lambert L,Chae MH,Yang JS,Duffy PE

更新日期：2018-05-17 00:00:00

abstract：BACKGROUND:We assessed 2 investigational 11- and 12-valent vaccines, containing capsular polysaccharides of 10 serotypes as in the pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) and CRM197-conjugated capsular polysaccharides of serotypes 19A (11-valent) or 19A and 6A (12-valent)....

journal_title：Vaccine

authors： Carmona Martinez A,Prymula R,Miranda Valdivieso M,Otero Reigada MDC,Merino Arribas JM,Brzostek J,Szenborn L,Ruzkova R,Horn MR,Jackowska T,Centeno-Malfaz F,Traskine M,Dobbelaere K,Borys D

更新日期：2019-01-03 00:00:00

abstract：AIMS:The study was designed to evaluate a novel cationic lipid DNA adjuvant (N3) and its function for HIV-1gp160/rev DNA plasmid delivered intranasally. The primary N3/HIV-DNA plasmid immunizations were boosted intranasally with a gp41 peptide in a anionic L3 adjuvant. This novel prime-boost strategy of mucosal immuniz...

journal_title：Vaccine

authors： Hinkula J,Devito C,Zuber B,Benthin R,Ferreira D,Wahren B,Schröder U

更新日期：2006-05-22 00:00:00

abstract：OBJECTIVES:We aimed to estimate vaccine effectiveness against severe measles based on the number of vaccine doses administered and the time since last vaccination. PATIENTS AND METHODS:We included measles cases aged at least 2 years and born since 1980 who were notified in France between 2006 and mid-2019. We consider...

journal_title：Vaccine

authors： Bonneton M,Antona D,Danis K,Aït-Belghiti F,Levy-Bruhl D

更新日期：2020-06-15 00:00:00

abstract：:Rubella is a mild disease characterized by low-grade fever, and a morbilliform rash, but causes congenital defects in neonates born from mothers who suffered from rubella during the pregnancy. After many passages of wild-type rubella virus strains in various types of cultured cells, five live attenuated rubella vaccin...

journal_title：Vaccine

authors： Otsuki N,Abo H,Kubota T,Mori Y,Umino Y,Okamoto K,Takeda M,Komase K

更新日期：2011-02-24 00:00:00

abstract：:Viral hemorrhagic septicemia (VHS) in olive flounder (Paralichthys olivaceus) remains an unsolved health problem in Korean aquaculture. Vaccination plays a significant role in modern aquaculture, and the duration of protection provided is of vital importance. Here, we have demonstrated the efficacy, duration of protec...

journal_title：Vaccine

authors： Vinay TN,Kim YJ,Jung MH,Kim WS,Kim DH,Jung SJ

更新日期：2013-09-23 00:00:00

abstract：BACKGROUND:Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2-14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharide vaccines can be overco...

journal_title：Vaccine

authors： Capeding MR,Teshome S,Saluja T,Syed KA,Kim DR,Park JY,Yang JS,Kim YH,Park J,Jo SK,Chon Y,Kothari S,Yang SY,Ham DS,Ryu JH,Hwang HS,Mun JH,Lynch JA,Kim JH,Kim H,Excler JL,Sahastrabuddhe S

更新日期：2018-06-18 00:00:00

abstract：:General vaccination with the 7-valent pneumococcal conjugate vaccine was recommended in Germany in July 2006 for all children <2 years. The proportion of reported invasive pneumococcal disease (IPD) caused by vaccine serotypes before vaccine introduction was considerably lower than in the US. We report data from natio...

journal_title：Vaccine

authors： Rückinger S,van der Linden M,Reinert RR,von Kries R,Burckhardt F,Siedler A

更新日期：2009-06-24 00:00:00

abstract：:We investigated the influence of the site of administration of DNA vaccine on the induced immune response. DNA vaccines were administered by electroporation at three different sites: tibial cranial muscle, abdominal skin and ear pinna. Aiming to draw general conclusions about DNA vaccine delivery, we successively used...

journal_title：Vaccine

authors： Vandermeulen G,Vanvarenberg K,De Beuckelaer A,De Koker S,Lambricht L,Uyttenhove C,Reschner A,Vanderplasschen A,Grooten J,Préat V

更新日期：2015-06-22 00:00:00

abstract：:The glutamate-rich protein (GLURP) of P. falciparum is the target of cytophilic antibodies which are significantly associated with protection against clinical malaria. A phase 1 clinical trial was conducted in healthy adult volunteers with the long synthetic peptide (LSP) GLURP(85-213) combined with either Aluminum Hy...

journal_title：Vaccine

authors： Hermsen CC,Verhage DF,Telgt DS,Teelen K,Bousema JT,Roestenberg M,Bolad A,Berzins K,Corradin G,Leroy O,Theisen M,Sauerwein RW

更新日期：2007-04-12 00:00:00

abstract：:Capsular polysaccharides of Streptococcus pneumoniae are used to formulate polyvalent pneumococcal vaccines. A sensitive method, using high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD), has been developed to quantify the contamination of pneumococcal capsular polysaccharides...

journal_title：Vaccine

authors： Talaga P,Bellamy L,Moreau M

更新日期：2001-04-06 00:00:00

abstract：:The presence of foot-and-mouth disease (FMD) in a country is a major obstacle to the development of agriculture because of its adverse effects on livestock production and agricultural exports. The eradication of FMD in sub-saharan Africa by the implementation of slaughtering-out is impractical for various reasons, but...

journal_title：Vaccine

authors： Hunter P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Since special efforts are necessary to vaccinate people living far from fixed vaccination posts, decision makers are interested in knowing the economic value of such efforts. METHODS:Using our immunization geospatial information system platform and a measles compartment model, we quantified the health and e...

journal_title：Vaccine

authors： Lee BY,Brown ST,Haidari LA,Clark S,Abimbola T,Pallas SE,Wallace AS,Mitgang EA,Leonard J,Bartsch SM,Yemeke TT,Zenkov E,Ozawa S

更新日期：2019-04-17 00:00:00

abstract：:It is accepted that booster vaccinations of chickens with live Salmonella vaccines are essential part of vaccinations schemes to induce an effective adaptive immune response. As manufacturer of registered live Salmonella vaccines recommend different times of booster the question raises whether the duration between the...

journal_title：Vaccine

authors： Methner U

更新日期：2018-05-17 00:00:00

abstract：:We have demonstrated that vaccination of turkeys with an unformulated DNA vaccine induces significant protection against Chlamydophila (Cp.) psittaci infections. Nevertheless, the immunogenicity of the DNA vaccine can still be improved by increasing translation and transfection efficiency. Therefore, the ompA codon wa...

journal_title：Vaccine

authors： Verminnen K,Beeckman DS,Sanders NN,De Smedt S,Vanrompay DC

更新日期：2010-04-19 00:00:00

abstract：:Clostridium difficile is a pathogen with increasing severity for which host antibody responses provide protection from disease. DNA vaccination has several advantages compared to traditional vaccine methods, however no study has examined this platform against C. difficile toxins. A synthetic gene was created encoding ...

journal_title：Vaccine

authors： Gardiner DF,Rosenberg T,Zaharatos J,Franco D,Ho DD

更新日期：2009-06-02 00:00:00

abstract：BACKGROUD:Influenza viruses cause substantial morbidity, especially in older age groups. Thus, they are amongst high priority groups for routine vaccination. However, vaccine-induced immune responses and effectiveness were reported as relatively low. This study aims to systemically compare the immune responses elicited...

journal_title：Vaccine

authors： Boonnak K,Dhitavat J,Thantamnu N,Kosoltanapiwat N,Auayporn M,Jiang L,Puthavathana P,Pitisuttithum P

更新日期：2017-12-19 00:00:00

abstract：:Vaccine safety fears following media reports of adverse events led to low (50.3%) coverage in a supplementary measles-rubella immunization campaign in Georgia in 2008. Review of adverse events associated with the campaign identified 432 reports (<0.1% of ∼ 493,000 vaccinees) including 338 (78.2%) cases of syncope. The...

journal_title：Vaccine

authors： Khetsuriani N,Imnadze P,Baidoshvili L,Jabidze L,Tatishili N,Kurtsikashvili G,Lezhava T,Laurent E,Martin R

更新日期：2010-09-07 00:00:00

abstract：:First year medical students at an allopathic medical school regional campus were asked to complete a 10-question survey at both the beginning and the conclusion of a required course on immunology, hematology and oncology. The survey was designed to solicit student attitudes about vaccination and the students' level of...

journal_title：Vaccine

authors： Onello E,Friedrichsen S,Krafts K,Simmons G Jr,Diebel K

更新日期：2020-01-22 00:00:00

abstract：:New and improved vaccines and delivery systems are increasingly being developed for prevention, treatment and diagnosis of human diseases. Prior to their use in humans, all new biological products must undergo pre-clinical evaluation. These pre-clinical studies are important not only to establish the biological proper...

journal_title：Vaccine

authors： Sesardic D

更新日期：2006-04-12 00:00:00

abstract：:Domestic ducks remain a major source of zoonotic Salmonella enterica infections for man worldwide and approaches to protection should include vaccine-mediated immunity. With this in mind we developed several genetically defined mutants in a virulent duck Salmonella typhimurium isolate TT-1. From initial tests for viru...

journal_title：Vaccine

authors： Tang T,Gao Q,Barrow P,Wang M,Cheng A,Jia R,Zhu D,Chen S,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-10-13 00:00:00

abstract：:Lyme borreliosis (LB) is the most common vector-borne disease in the northern hemisphere and there is no vaccine available for disease prevention. The majority of LB cases in Europe are caused by four different Borrelia species expressing six different OspA serotypes, whereas in the US only one of these serotypes is p...

journal_title：Vaccine

authors： Comstedt P,Hanner M,Schüler W,Meinke A,Schlegl R,Lundberg U

更新日期：2015-11-04 00:00:00