Telomeres and telomerases: intimations of immortality.

Abstract:

:There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immortalization'. Telomeres, structures that cap the chromosomes, are related to cell longevity and are regulated by a ribonucleoprotein called telomerase. This review describes the possible roles of telomeres and telomerase in the malignant process.

authors

Crocker J

doi

10.1097/00042737-200108000-00002

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

889-90

issue

8

eissn

0954-691X

issn

1473-5687

journal_volume

13

pub_type

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