Non-surgical therapies of hepatocellular carcinoma.

abstract：OBJECTIVE:Enterally administered glucose modifies gut sensation, diminishes hunger, and slows gastric emptying by suppressing antral motility and stimulating pyloric pressures. We aimed to clarify the mechanism of small intestinal glucose sensing. METHODS:We studied eight healthy males twice, in random order. An antro...

journal_title：European journal of gastroenterology & hepatology

authors： Chaikomin R,Jones KL,Feinle-Bisset C,Meyer JH,Horowitz M,Rayner CK

更新日期：2009-03-01 00:00:00

abstract：:Chronic hepatitis B continues to be a major global health burden. It accounts for a substantial impact on health care resources and finances in many parts of the world including Europe. Natural history and disease spectrum are varied, depending on when and how the infection is acquired. The chronic infective state inc...

journal_title：European journal of gastroenterology & hepatology

authors： Massoumi H,Martin P,Tan HH

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Under-recognition of alpha-1 antitrypsin deficiency (AATD) is well documented in AATD-lung disease but is rarely reported in patients with liver cirrhosis requiring liver transplantation. This report examines the frequency of newly diagnosed AATD based on pathologic examination of explanted livers following l...

journal_title：European journal of gastroenterology & hepatology

authors： Shah RS,Alsuleiman B,Bena J,Stoller JK,Wakim-Fleming J

更新日期：2020-11-30 00:00:00

abstract：OBJECTIVE:We sought a good indicator cell line to use in detecting the vacuolating toxin produced by Helicobacter pylori and in examining the characteristics of the toxin. DESIGN AND METHODS:Using five cell lines [baby hamster kidney (BHK-21), human amnion (FL), human uterine cancer (HeLa), rabbit kidney (RK-13) and A...

journal_title：European journal of gastroenterology & hepatology

authors： Kamiya S,Kai M,Ozawa A,Kobayashi H,Shirai T,Harasawa S,Miwa T

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Chronic hepatitis C (CHC) is a leading cause of liver fibrosis. OBJECTIVE:To compare utility of liver transient elastography, AST-to-platelet ratio index (APRI), fibrosis-4 index (FIB4), Forns Index and Goteborg University cirrhosis index (GUCI) in predicting fibrosis stage assessed by liver biopsy in Egypt...

journal_title：European journal of gastroenterology & hepatology

authors： Abdelsameea E,Alsebaey A,Abdel-Razek W,Ehsan N,Morad W,Salama M,Waked I

更新日期：2020-12-01 00:00:00

abstract：:The results of systemic treatments for hepatocellular carcinoma are currently disappointing. In patients with advanced disease, none of the tested treatments (particularly systemic chemotherapy or hormonal treatment, such as tamoxifen) demonstrated an unequivocal benefit in terms of survival, and the trials including ...

journal_title：European journal of gastroenterology & hepatology

authors： Ganne-Carrié N,Trinchet JC

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:One study has suggested that markers of acute hepatitis E virus (HEV) infection are present in 3.6% of patients with severe alcoholic hepatitis (AH). However, validation of these preliminary results is lacking, as well as the impact of HEV infection on the 6-month survival. AIMS:The aims of this study were ...

journal_title：European journal of gastroenterology & hepatology

authors： Rudler M,Thibault V,Mouri S,Akhavan S,Mallet M,Charlotte F,Poynard T,Thabut D

更新日期：2015-12-01 00:00:00

abstract：:Hereditary hyperferritinaemia-cataract syndrome (HHCS) is a relatively rare disorder with an autosomal dominant trait. It can be caused by various mutations within the iron responsive element (IRE) of the L-ferritin gene. These mutations result in an increased translation of L-ferritin mRNA and consequently the accumu...

journal_title：European journal of gastroenterology & hepatology

authors： Ferrante M,Geubel AP,Fevery J,Marogy G,Horsmans Y,Nevens F

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Postinfective bile acid malabsorption comprises a group of patients with a history of an episode of acute gastroenteritis triggering chronic diarrhoea. We identified these patients retrospectively from our medical records and assessed their long-term clinical course. MATERIALS AND METHODS:We examined the re...

journal_title：European journal of gastroenterology & hepatology

authors： Menon S,Jones BJ

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Hyperuricemia is a significant risk factor for nonalcoholic fatty liver disease (NAFLD). It may also have an impact on the histologic severity of NAFLD. However, data on this association are limited. We conducted this meta-analysis to investigate the relationship of serum uric acid with liver histologic seve...

journal_title：European journal of gastroenterology & hepatology

authors： Jaruvongvanich V,Ahuja W,Wirunsawanya K,Wijarnpreecha K,Ungprasert P

更新日期：2017-09-01 00:00:00

abstract：AIM:Transient elastography is a noninvasive and reliable method for the assessment of liver stiffness. This study aimed to assess liver stiffness of asymptomatic liver fluke disease patients by FibroScan and evaluate the factors influencing liver stiffness. METHODS:Overall, 65 patients were prospectively recruited fro...

journal_title：European journal of gastroenterology & hepatology

authors： Gao Q,Shao D,Pan A,Gao M,Liu Z,Liang C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Serum biomarkers of steatosis such as the SteatoTest are recommended for large-scale screening studies, because imaging is less accessible and more expensive. AIMS:The primary aim of this retrospective analysis of prospective studies was to construct a new SteatoTest-2 that was not inferior to the reference...

journal_title：European journal of gastroenterology & hepatology

authors： Poynard T,Peta V,Munteanu M,Charlotte F,Ngo Y,Ngo A,Perazzo H,Deckmyn O,Pais R,Mathurin P,Myers R,Loomba R,Ratziu V,FLIP consortium, the FibroFrance-CPAM group, the FibroFrance-Obese group, and the Selonsertib group.

更新日期：2019-03-01 00:00:00

abstract：:Coeliac disease is a T-cell-mediated enteropathy induced by gluten. A minority of patients who fail to respond to a gluten-free diet may require intervention with immunomodulating drugs. We report a case of refractory coeliac disease where remission was induced by the anti-tumour necrosis factor-alpha antibody inflixi...

journal_title：European journal of gastroenterology & hepatology

authors： Turner SM,Moorghen M,Probert CS

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Correa's hypothesis proposes that gastric carcinogenesis is due to atrophic gastritis and hypochlorhydria which permit gastric bacterial colonization, the reduction of dietary nitrates to nitrites and the formation of potentially carcinogenic N-nitroso compounds (NOCs). OBJECTIVE:To test the hypothesis that...

journal_title：European journal of gastroenterology & hepatology

authors： Viani F,Siegrist HH,Pignatelli B,Cederberg C,Idström JP,Verdu EF,Fried M,Blum AL,Armstrong D

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:As treatment of steroid-dependent patients with inflammatory bowel disease (IBD) is controversial, we analysed the efficacy and tolerance of 6-mercaptopurine (6-MP) and methotrexate (MTX) added to prednisone in increasing and maintaining the disease remission rate. METHODS:Seventy-two steroid-dependent IBD ...

journal_title：European journal of gastroenterology & hepatology

authors： Maté-Jiménez J,Hermida C,Cantero-Perona J,Moreno-Otero R

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Postoperative clinical and endoscopic recurrence is common in Crohn's disease. AIM:We aimed to assess postoperative recurrence and management in a cross-sectional patient cohort in one specialist unit, before the introduction of a uniform postoperative preventive strategy. METHODS:Review of patients who ha...

journal_title：European journal of gastroenterology & hepatology

authors： Ng SC,Lied GA,Arebi N,Phillips RK,Kamm MA

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The PGAA index was one of the first composite liver fibrosis markers. This study aims, prospectively, to confirm the diagnostic value of PGAA and Fibrotest in patients with alcoholic liver disease and to compare their diagnostic performances. PATIENTS AND METHODS:We prospectively included 200 conse...

journal_title：European journal of gastroenterology & hepatology

authors： Naveau S,Essoh BM,Ghinoiu M,Marthey L,Njiké-Nakseu M,Balian A,Lachgar M,Prévot S,Perlemuter G

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Intestinal metaplasia is a well-established risk factor in the development of stomach cancer. However, since the specificity is low it would be of great practical value to find a marker to separate cases of intestinal metaplasia into low and high risk for progression to dysplasia/carcinoma. So far this has no...

journal_title：European journal of gastroenterology & hepatology

authors： Gulmann C,Grace A,Leader M,Butler D,Patchett S,Kay E

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:Hepcidin is an endogenous antimicrobial peptide with a key role in iron homoeostasis. Hepcidin is similar to defensin, the deficiency of which is associated with Crohn's disease. To date there has been no validated method to reliably assay serum hepcidin. We studied iron indices in inflammatory bowel disease ...

journal_title：European journal of gastroenterology & hepatology

authors： Arnold J,Sangwaiya A,Bhatkal B,Geoghegan F,Busbridge M

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Several classifications of mucosal morphology have been proposed in Barrett oesophagus using narrow-band imaging (NBI). We evaluated a simplified classification in which only the regularity of mucosal and vascular patterns were evaluated. AIM:To assess the inter and intraobserver agreement and the correlati...

journal_title：European journal of gastroenterology & hepatology

authors： Alvarez Herrero L,Curvers WL,Bansal A,Wani S,Kara M,Schenk E,Schoon EJ,Lynch CR,Rastogi A,Pondugula K,Weusten B,Sharma P,Bergman JJ

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:It is unclear how the transient remission of nonalcoholic fatty liver disease (NAFLD) affects incident type 2 diabetes mellitus (T2DM). Here, we sought to determine the effect of the transient remission of NAFLD on incident T2DM in Japanese men. MATERIALS AND METHODS:We used a population-based health chec...

journal_title：European journal of gastroenterology & hepatology

authors： Fukuda T,Hamaguchi M,Kojima T,Mitsuhashi K,Hashimoto Y,Ohbora A,Kato T,Nakamura N,Fukui M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Screening colonoscopy is less effective in preventing proximal colon cancers than distal colon cancers. A repeat examination of the right side of the colon may increase the lesion detection. The study aimed to assess the results of a second examination of the right side of the colon with forward-view or retr...

journal_title：European journal of gastroenterology & hepatology

authors： Ai X,Qiao W,Han Z,Tan W,Bai Y,Liu S,Zhi F

更新日期：2018-02-01 00:00:00

abstract：AIM:The aim of this research was to assess how the use of sedation during colonoscopy influences patient anxiety, fear, satisfaction, and acceptance of repeat examinations. MATERIALS AND METHODS:A prospective case-control study quantifying the anxiety and fears of patients appointed for colonoscopy, comparing patients...

journal_title：European journal of gastroenterology & hepatology

authors： Baudet JS,Aguirre-Jaime A

更新日期：2012-07-01 00:00:00

abstract：:Gastrointestinal stromal tumour (GIST) has been immunohistochemically defined as the tumour lacking differentiation towards either leiomyomatous tumour or schwannoma. We report a 75-year-old man who underwent an abdominoperineal resection of a large submucosal tumour of the rectum. The excised specimen was revealed to...

journal_title：European journal of gastroenterology & hepatology

authors： Shibata Y,Ueda T,Seki H,Yagihashi N

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:The potential diagnostic value of performing Doppler measurements of liver vasculature to assess early stages of liver fibrosis has not been established. Due to the potential clinical impact, this study focused on the correlation between Doppler measurements and histologically proven liver fibrosis. METHODS:...

journal_title：European journal of gastroenterology & hepatology

authors： Bernatik T,Strobel D,Hahn EG,Becker D

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of membrane lipid composition on the susceptibility to bile salt damage and protection. DESIGN:Artificial model cholesterol/phospholipid (c/p) membranes (vesicles) with a varying cholesterol (0-15 mM) and phospholipid content (3-30 mM), and with a c/p ratio ranging up to 1.70, were...

journal_title：European journal of gastroenterology & hepatology

authors： van de Heijning BJ,van den Broek AM,van Berge-Henegouwen GP

更新日期：1997-05-01 00:00:00

abstract：:Nitric oxide (NO) can exert both protective and proinflammatory actions in the gastrointestinal tract. NO, formed physiologically by constitutive NO synthases, regulates vascular tone, protects the microvasculature from injury, and modulates adhesion of inflammatory cells. In contrast, expression of an inducible isofo...

journal_title：European journal of gastroenterology & hepatology

authors： Whittle BJ

更新日期：1997-11-01 00:00:00

abstract：:Syndecan expression, or the lack thereof by tumor cells, has been associated with poor prognosis in several types of cancer, including colorectal cancer. Syndecan is a heparan sulfate proteoglycan involved in tumor adhesion, invasion, and metastasis. In addition, the expression of the enzyme heparanase by cancer cells...

journal_title：European journal of gastroenterology & hepatology

authors： Giordano RJ

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:Clostridium difficile infection (CDI) is an acute gastrointestinal infection caused by anaerobic, toxin-producing bacteria. During the course of CDI, there is a general inflammatory state. In order to gain a deeper understanding of the role of fatty acids (FAs) in the pathogenesis of acute infection we analy...

journal_title：European journal of gastroenterology & hepatology

authors： Dróżdż M,Gdula-Argasińska J,Biesiada G,Jurczyszyn A,Perucki W,Wołkow P,Borys A,Sroczyńska K,Zając A,Librowski T,Garlicki A,Czepiel J

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Liver biopsy is considered as the gold standard for assessing nonalcoholic fatty liver disease (NAFLD) histologic lesions in patients with morbid obesity. The aim of this study was to determine the diagnostic utility of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis ...

journal_title：European journal of gastroenterology & hepatology

authors： Lassailly G,Caiazzo R,Hollebecque A,Buob D,Leteurtre E,Arnalsteen L,Louvet A,Pigeyre M,Raverdy V,Verkindt H,Six MF,Eberle C,Patrice A,Dharancy S,Romon M,Pattou F,Mathurin P

更新日期：2011-06-01 00:00:00