Gastrointestinal stromal tumour of the rectum.

Abstract:

:Gastrointestinal stromal tumour (GIST) has been immunohistochemically defined as the tumour lacking differentiation towards either leiomyomatous tumour or schwannoma. We report a 75-year-old man who underwent an abdominoperineal resection of a large submucosal tumour of the rectum. The excised specimen was revealed to be an elastic soft tumour, 8 x 7 x 6 cm in size, which histologically consisted of spindle-shaped cells without nuclear atypia. The mitotic count was fewer than 2 per 10 high-power fields. The tumour cells were positive for staining of CD34 and c-kit protein, while the lesions were negative for alpha-smooth muscle actin, HHF-35, neuron-specific enolase, and S-100 protein. The diagnosis of GIST was confirmed by immunohistochemical examination of the tumour. From these findings, the present case is thought to be potentially malignant, and a long-term follow-up observation is needed for the case.

authors

Shibata Y,Ueda T,Seki H,Yagihashi N

doi

10.1097/00042737-200103000-00012

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

283-6

issue

3

eissn

0954-691X

issn

1473-5687

journal_volume

13

pub_type

杂志文章
  • Immunoproliferative small intestinal disease in Greece: presentation of 13 cases including two from Albania.

    abstract:OBJECTIVES:Immunoproliferative small intestinal disease (IPSID) represents a spectrum of clinicopathological entities including alpha-chain disease and other types of lymphoplasmacytic proliferations of the lamina propria of the small intestine, presenting with severe malabsorption. IPSID has been described mainly in t...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/01.meg.0000228976.64774.04

    authors: Economidou I,Manousos ON,Triantafillidis JK,Vaslamatzis MM,Zafiropoulou R,Papadakis T

    更新日期:2006-09-01 00:00:00

  • Ethnic variation in colorectal cancer risk following a positive faecal occult blood test in an English bowel cancer screening programme centre.

    abstract:BACKGROUND AND AIMS:The literature on colorectal cancer (CRC) screening and ethnic diversity is dominated by studies from the USA. There are no such published data from the UK bowel cancer screening programme (BCSP) population. The Wolverhampton Bowel Cancer Screening Centre serves a population of 900,000 in the Black ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000443

    authors: Padmanabhan H,Widlak M,Nevill A,McKaig B,Brookes M,Veitch A

    更新日期:2015-11-01 00:00:00

  • Survival analysis after gastrostomy: a single-centre, observational study comparing radiological and endoscopic insertion.

    abstract:OBJECTIVES:Percutaneous endoscopic gastrostomy (PEG) using the pull through technique is the most widely used insertion method. An alternative is a per-oral image-guided gastrostomy (PIG), which may be advantageous in high-risk patients. As there are no large studies comparing PEG against PIG, we wished to analyse mort...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328332d2dd

    authors: Leeds JS,McAlindon ME,Grant J,Robson HE,Lee FK,Sanders DS

    更新日期:2010-05-01 00:00:00

  • Perceptions of gastroenterologists and nurses regarding irritable bowel syndrome and inflammatory bowel disease.

    abstract:OBJECTIVE:Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) have similar symptoms, and both adversely affect patients' quality of life. The objective of this study was to compare the perceptions of physicians and nurses regarding IBS and IBD. METHODS:The Illness Perception Questionnaire Revised, adap...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328348a552

    authors: Dickman R,Segev M,Levi S,Reicher-Atir R,Steinmetz A,Horev N,Niv Y

    更新日期:2011-09-01 00:00:00

  • Anticardiolipin antibodies in chronic viral hepatitis. Do they have clinical consequences?

    abstract::Antiphospholipid antibodies are a heterogeneous group of acquired autoantibodies that react with anionic phospholipids, such as cardiolipin. Anticardiolipin antibodies (ACAs) are frequently found in patients with systemic lupus erythematosus and other autoimmune disorders and can react with the phospholipid alone or b...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 评论,杂志文章

    doi:10.1097/01.meg.0000059144.68845.61

    authors: Yuste JR,Prieto J

    更新日期:2003-07-01 00:00:00

  • Primary biliary cirrhosis and idiopathic retroperitoneal fibrosis: a rare association.

    abstract::Primary biliary cirrhosis has rarely been reported to be associated with idiopathic retroperitoneal fibrosis. We describe the case of a 57-year-old man who was confirmed to have both conditions, reflecting the likely autoimmune aetiopathogenesis common to both disorders. ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200207000-00013

    authors: Tang KH,Schofield JB,Powell-Jackson PR

    更新日期:2002-07-01 00:00:00

  • Small mucosal carcinoma of the stomach with para-aortic lymph node metastasis: a case report and review of the literature.

    abstract::A 38-year-old woman presented with a mucosal gastric carcinoma measuring 0.7 x 0.5 cm and para-aortic lymph node metastasis. Radiographic and endoscopic studies showed a small depressed lesion on the anterior border of the gastric angle, which was classified as a type II c + III lesion. Histological examination of the...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:

    authors: Miyaji M,Ogoshi K,Nakamura K,Kondo Y,Tajima T,Makuuchi H,Sato S,Osamura Y

    更新日期:1999-03-01 00:00:00

  • Short-acting general anaesthesia facilitates therapeutic ERCP in frail elderly patients with benign extra-hepatic biliary disease.

    abstract:AIMS AND OBJECTIVES:To ascertain whether therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for benign biliary disease in frail elderly patients with comorbid conditions can be safely undertaken in a district general hospital, and whether the procedure is facilitated by the use of short-acting general an...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200012040-00014

    authors: Cocking JB,Ferguson A,Mukherjee SK,Giancola G

    更新日期:2000-04-01 00:00:00

  • In-vivo effect of nicotine on cytokine production by human non-adherent mononuclear cells.

    abstract:OBJECTIVE:Ulcerative colitis (UC) is predominantly a disease of non-smokers and treatment with transdermal nicotine improves symptoms in UC patients, whereas smoking seems to have a deleterious effect in patients with Crohn's disease (CD). In CD the cytokine profile is of a dominant TH1 (T helper 1) pattern whereas in ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199610000-00016

    authors: Madretsma S,Wolters LM,van Dijk JP,Tak CJ,Feyerabend C,Wilson JH,Zijlstra FJ

    更新日期:1996-10-01 00:00:00

  • Intra-oesophageal pH profiles and pharmacokinetics of pantoprazole and esomeprazole: a crossover study in patients with gastro-oesophageal reflux disease.

    abstract:AIM:To compare the effect of pantoprazole and esomeprazole on intra-oesophageal pH and investigate their pharmacokinetics in patients with symptomatic gastro-oesophageal reflux disease (GORD). METHODS:Double-blind, randomized, two-period crossover study. Caucasian men with symptomatic GORD (n=48) were selected on the ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.meg.0000059157.46867.42

    authors: Simon B,Müller P,Pascu O,Gatz G,Sander P,Huber R,Mascher H

    更新日期:2003-07-01 00:00:00

  • Expression of Fas antigen in liver tissue of patients with chronic hepatitis B and C.

    abstract:OBJECTIVES:Cells infected with the hepatitis B or C virus can be eliminated by an immune response mediated by cytotoxic T cells. Recently, the Fas Ligand has been detected on the surface of cytotoxic T cells, and is thought to induce cells to apoptosis by adhering to the Fas antigen. METHODS:To evaluate the role of th...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200403000-00015

    authors: Oksuz M,Akkiz H,Isiksal YF,Seydaoglu G,Serin M,Kayaselcuk F,Abayli B,Tuncer I

    更新日期:2004-03-01 00:00:00

  • Acute inflammatory intestinal vascular lesions and in situ abnormalities of the plasminogen activation system in Crohn's disease.

    abstract:OBJECTIVES:The distribution of the intestinal vascular lesions and their relation with the fibrinolysis process are poorly known in Crohn's disease (CD). The mediators of the plasminogen activator system, namely urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and plasminogen activa...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199910000-00007

    authors: Desreumaux P,Huet G,Zerimech F,Gambiez L,Balduyck M,Baron P,Degand P,Cortot A,Colombel JF,Janin A

    更新日期:1999-10-01 00:00:00

  • Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection.

    abstract::Treatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the i...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200102000-00016

    authors: Campbell S,Ghosh S

    更新日期:2001-02-01 00:00:00

  • Hepatitis C treatment for multimorbid patients with substance use disorder in a primary care-based integrated treatment centre: a retrospective analysis.

    abstract:OBJECTIVES/BACKGROUND:The population of people who use drugs (PWUD) has the highest prevalence of hepatitis C virus (HCV) infections in Europe. PWUD are multimorbid patients who are difficult to integrate into existing healthcare systems. In our study, we evaluated the feasibility of providing HCV treatment within opio...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e32836140bb

    authors: Brunner N,Senn O,Rosemann T,Falcato L,Bruggmann P

    更新日期:2013-11-01 00:00:00

  • Prevention of recurrence of oesophageal stricture, a comparison of lansoprazole and high-dose ranitidine.

    abstract:OBJECTIVE:To determine the efficacy of lansoprazole 30 mg given in the morning compared with high-dose ranitidine 300 mg twice daily in the treatment of patients with oesophageal strictures. DESIGN:A multicentre, outpatient, double-blind, parallel group, prospectively randomized clinical trial. PATIENTS:One hundred a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Swarbrick ET,Gough AL,Foster CS,Christian J,Garrett AD,Langworthy CH

    更新日期:1996-05-01 00:00:00

  • Computer simulator among experts involved in screening colonoscopy.

    abstract:BACKGROUND:In the era of screening colonoscopy, assessment of operator competence is warranted. AIM:To evaluate feasibility of a computer simulator (CS) use for assessment of competence in colonoscopy by investigating performance of expert endoscopists at CS. SUBJECTS:Twenty expert endoscopists involved in screening ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e32832ad615

    authors: Cantù P,Grigolon A,Caparello C,Bravi I,Tenca A,Elvevi A,Nicita MT,Duca P,Conte D,Penagini R

    更新日期:2010-01-01 00:00:00

  • Hepatitis C in a Mobile Low-Threshold Methadone Program.

    abstract:INTRODUCTION:Data on the epidemiology of hepatitis C among individuals who use drugs in low-threshold settings are lacking, although crucial to assess the burden of disease and aid in the design of treatment strategies. OBJECTIVE:The aim of this study was to characterize the epidemiology and disease related to hepatit...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000843

    authors: Silva MJ,Pereira C,Loureiro R,Balsa C,Lopes P,Água-Doce I,Belo E,Martins HC,Coutinho R,Pádua E

    更新日期:2017-06-01 00:00:00

  • One-week therapy with pantoprazole versus ranitidine bismuth citrate plus two antibiotics for Helicobacter pylori eradication.

    abstract:AIM:A combination of omeprazole plus amoxycillin (Amo) and clarithromycin (CIa) for 7 days has been studied extensively. However, the role of other proton pump inhibitors, such as pantoprazole (Pan), in this therapy is not well known. On the other hand, ranitidine bismuth citrate (RBC) also seems to be effective when c...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00042737-200012050-00003

    authors: Gisbert JP,Carpio D,Marcos S,Gisbert JL,García Grávalos R,Pajares JM

    更新日期:2000-05-01 00:00:00

  • Influence of biliary anastomosis on recovery from secondary biliary cirrhosis.

    abstract:OBJECTIVE:The influence of choledochoduodenostomy and choledochojejunostomy on the repair of hepatic lesions secondary to biliary obstruction is not well known. The aim of the present study was to compare the effects of choledochoduodenostomy and choledochojejunostomy on the recovery of these lesions in rats with bilia...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283551fed

    authors: dos Santos JS,Kemp R,de Andrade MF,Neder L

    更新日期:2012-09-01 00:00:00

  • Hyperuricemia is associated with nonalcoholic fatty liver disease activity score in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis.

    abstract:BACKGROUND:Hyperuricemia is a significant risk factor for nonalcoholic fatty liver disease (NAFLD). It may also have an impact on the histologic severity of NAFLD. However, data on this association are limited. We conducted this meta-analysis to investigate the relationship of serum uric acid with liver histologic seve...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MEG.0000000000000931

    authors: Jaruvongvanich V,Ahuja W,Wirunsawanya K,Wijarnpreecha K,Ungprasert P

    更新日期:2017-09-01 00:00:00

  • The long-term follow-up of patients with endoscopically diagnosed reflux oesophagitis with specific emphasis to complaints.

    abstract:INTRODUCTION:Patients with gastroesophageal reflux disease (GERD) need long-term treatment with acid-suppressive therapy. Data on long-term follow-up are very rare. For this reason, a study was performed to detect complaints many years after diagnosis. PATIENTS AND METHODS:All patients diagnosed with reflux oesophagit...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32834b8d18

    authors: Loffeld SM,Dackus GM,Loffeld RJ

    更新日期:2011-11-01 00:00:00

  • Length of endoscopic workup in gastrointestinal bleeding.

    abstract:BACKGROUND:The number of procedures utilized in the general management of gastrointestinal bleeding (GIB) has not been investigated previously. We used the National Endoscopic Database of the Clinical Outcomes Research Initiative for an observational study to analyze the average length of workup in GIB. METHODS:The el...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000693

    authors: Woodward Z,Williams JL,Sonnenberg A

    更新日期:2016-10-01 00:00:00

  • Hepatic stellate cell activation and hepatic fibrosis in children with type 1 autoimmune hepatitis: an immunohistochemical study of paired liver biopsies before treatment and after clinical remission.

    abstract:OBJECTIVES:The activation of hepatic stellate cells (HSC) is considered the most important event in hepatic fibrogenesis. The precise mechanism of this process is unknown in autoimmune hepatitis (AIH), and more evidence is needed on the evolution of fibrosis. The aim of this study was to assess these aspects in childre...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328326cab6

    authors: Maia JM,Maranhão Hde S,Sena LV,Rocha LR,Medeiros IA,Ramos AM

    更新日期:2010-03-01 00:00:00

  • hMLH1 promoter methylation and JC virus T antigen presence in the tumor tissue of colorectal cancer Israeli patients of different ethnic groups.

    abstract:BACKGROUND:Hypermethylation of tumor suppressor genes' promoter and JC virus infection may be etiologic factors in the development of colorectal cancer (CRC). OBJECTIVES:To look at both JC virus T antigen and hMLH1 promoter methylation in CRC tissue in Israeli ethnic groups with different incidence of CRC. METHODS:Tw...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32832e9d2c

    authors: Niv Y,Vilkin A,Brenner B,Kendel Y,Morgenstern S,Levi Z

    更新日期:2010-08-01 00:00:00

  • Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease.

    abstract:OBJECTIVE:Recent studies have suggested that endotoxin-induced cytokines play an important role in nonalcoholic fatty liver disease (NAFLD). Rifaximin is a nonabsorbable antibiotic that might act on Gram-negative bacteria, thereby inhibiting endotoxin proinflammatory cytokine production in patients with NAFLD. Our aim ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000348

    authors: Gangarapu V,Ince AT,Baysal B,Kayar Y,Kılıç U,Gök Ö,Uysal Ö,Şenturk H

    更新日期:2015-07-01 00:00:00

  • Characterization of serum irisin in patients with severe acute pancreatitis.

    abstract:BACKGROUND:Irisin, as a novel and versatile hormone secreted by skeletal myocytes and fat tissues, is reported to be involved in inflammation-related diseases; one of the main characteristics of severe acute pancreatitis (SAP) is inflammatory responses. This study aims to describe the characteristics of irisin in SAP. ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001454

    authors: Chen S,Wang L,Gao X,Chen M,Zeng Z,Zhao L

    更新日期:2019-08-01 00:00:00

  • Total bile acid levels are associated with left atrial volume and cardiac output in patients with cirrhosis.

    abstract:BACKGROUND AND AIMS:Bile acids (BAs) are potent signaling molecules involved in the regulation of several metabolic and functional aspects of cardiovascular homeostasis. BA pool alteration in cirrhosis may contribute toward the development of hemodynamic and cardiac disturbances. We aimed to investigate the association...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001043

    authors: Voiosu AM,Wiese S,Voiosu TA,Hove J,Bendtsen F,Møller S

    更新日期:2018-04-01 00:00:00

  • Infliximab in refractory coeliac disease.

    abstract::Coeliac disease is generally well controlled with gluten-free diet but a small proportion of patients require corticosteroids or immunomodulatory agents. Response to anti-tumour necrosis factor (anti-TNF) agents raises interesting questions about both the pathogenesis of coeliac disease and the mechanism of action of ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200506000-00002

    authors: Chaudhary R,Ghosh S

    更新日期:2005-06-01 00:00:00

  • Management of bleeding gastric varices: a single session of histoacryl injection may be sufficient.

    abstract:OBJECTIVE:Gastric variceal bleeding is one of the most feared complications of portal hypertension and hence merits investigation for its optimal therapy. We aimed to evaluate the efficacy and long-term outcome(s) of patients treated with a single session of histoacryl sclerotherapy for active gastric variceal bleeding...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000080

    authors: Khawaja A,Sonawalla AA,Somani SF,Abid S

    更新日期:2014-06-01 00:00:00

  • Colonic endocrine cells in patients with carcinoma of the colon.

    abstract:OBJECTIVE:To investigate the colonic endocrine cells in patients with colon carcinoma in order to establish a possible abnormality. PATIENTS:Twelve patients with colon adenocarcinoma (eight women and four men; mean age 69 years; range 52-88 years) were studied. As controls, macroscopically and histologically normal ti...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199806000-00015

    authors: El-Salhy M,Mahdavi J,Norrgård O

    更新日期:1998-06-01 00:00:00