abstract：OBJECTIVES:Alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) are used as tumour markers for the diagnosis of hepatocellular carcinoma (HCC). We investigate whether combined liver function marker such as gamma-glutamyl transferase (GGT) and aspartate aminotransferase (AST) with...

journal_title：European journal of gastroenterology & hepatology

authors： Ekmen N,Akalin Ç,Akyildiz M

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:Studies have suggested that coronavirus disease 2019 (COVID-19) appears to be more serious in patients with gastrointestinal symptoms. This meta-analysis was conducted to explore the relationship between gastrointestinal symptoms and the severity of COVID-19. METHODS:We searched PubMed, Web of Science, Scien...

journal_title：European journal of gastroenterology & hepatology

authors： Zeng W,Qi K,Ye M,Zheng L,Liu X,Hu S,Zhang W,Tang W,Xu J,Yu D,Wei Y

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Patients with nonalcoholic fatty liver disease (NAFLD) have sleep disruption. The aim of this study is to understand how underlying factors such as diet, degree of liver disease and morningness-eveningness tendencies contribute to this sleep disruption. METHODS:Patients with NAFLD were recruited from liver ...

journal_title：European journal of gastroenterology & hepatology

authors： Akram ST,Ewy MW,Said A

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Recent studies have revealed that combining of the platelet to lymphocyte ratio (PLR) and the neutrophil to lymphocyte ratio (NLR) [(combination of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio (CNP)] links with dismal prognosis in diverse cancers. Here, we elucidated the prognostic significance ...

journal_title：European journal of gastroenterology & hepatology

authors： Kong W,Qu E,Sheng N,Zhang J,Li X,Zheng J,Gao Y

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVES:Data on SARS-CoV-2 disease (COVID-19) in adult coeliac disease (CD) are lacking. The aim of the present study is to evaluate the epidemiology and clinical features of COVID-19 in adult coeliac patients regularly followed-up at our centre since January 2015. METHODS:Data about general health status and clini...

journal_title：European journal of gastroenterology & hepatology

authors： Schiepatti A,Alimenti E,Maimaris S,Nicolardi ML,Manzella La Barbera F,Baiardi P,Biagi F

更新日期：2021-01-04 00:00:00

abstract：OBJECTIVES:To assess performance and cutoffs of the 2-dimensional shear wave elastography technique available on the Aplio i800 ultrasound system (Canon Medical Systems, Japan), using transient elastography as reference standard, and to assess the correlation of shear-wave-speed dispersion with liver fibrosis or steato...

journal_title：European journal of gastroenterology & hepatology

authors： Ferraioli G,Maiocchi L,Dellafiore C,Tinelli C,Above E,Filice C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Several studies have reported associations of proton pump inhibitor (PPI) treatment with the incidence of complications and even increased mortality in patients with liver cirrhosis. Up to now, there are no studies on the impact of PPI treatment in patients with hepatocellular carcinoma (HCC). There...

journal_title：European journal of gastroenterology & hepatology

authors： Sturm L,Muller L,Schultheiss M,Binder B,Huber JP,Thimme R,Bettinger D

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Chronic hepatitis C (CHC) is a leading cause of liver fibrosis. OBJECTIVE:To compare utility of liver transient elastography, AST-to-platelet ratio index (APRI), fibrosis-4 index (FIB4), Forns Index and Goteborg University cirrhosis index (GUCI) in predicting fibrosis stage assessed by liver biopsy in Egypt...

journal_title：European journal of gastroenterology & hepatology

authors： Abdelsameea E,Alsebaey A,Abdel-Razek W,Ehsan N,Morad W,Salama M,Waked I

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Under-recognition of alpha-1 antitrypsin deficiency (AATD) is well documented in AATD-lung disease but is rarely reported in patients with liver cirrhosis requiring liver transplantation. This report examines the frequency of newly diagnosed AATD based on pathologic examination of explanted livers following l...

journal_title：European journal of gastroenterology & hepatology

authors： Shah RS,Alsuleiman B,Bena J,Stoller JK,Wakim-Fleming J

更新日期：2020-11-30 00:00:00

abstract：PURPOSE:The model of end-stage liver disease (MELD) score has been shown to predict 3-month prognosis following transjugular intrahepatic portosystemic stent shunt (TIPS) in liver cirrhosis; however, that score was derived from a mixed cohort, including patients with refractory ascites and variceal bleeding. This study...

journal_title：European journal of gastroenterology & hepatology

authors： Pitton MB,Zimmermann T,Mildenberger P,Weinmann A,Kloeckner R,Düber C,Mittler J,Hoppe-Lotichius M,Otto G

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early-onset colorectal cancer (eoCRC), defined as colorectal cancer (CRC) before the age of 50 is increasing in incidence. We evaluated exogenous and endogenous risk factors, and clinical features of eoCRC, compared to late-onset CRC (loCRC). METHODS:In this retrospective case-case study, pat...

journal_title：European journal of gastroenterology & hepatology

authors： Di Leo M,Zuppardo RA,Puzzono M,Ditonno I,Mannucci A,Antoci G,Russo Raucci A,Patricelli MG,Elmore U,Tamburini AM,Albarello L,Azzolini F,Bonura GF,Esposito D,Fanti L,Notaristefano C,Viale E,Perea J,Testoni PA,Rosati R

更新日期：2020-11-17 00:00:00

abstract：:Over the last decade, major advancements have been made in our understanding of both the beneficial and detrimental role that microorganisms play in our innate functioning. Research into the intestinal microbiota has moved from the laboratory into our medical clinics and is being put forth as an effective therapy for ...

journal_title：European journal of gastroenterology & hepatology

authors： Tamilarasan AG,Krishnananthan T

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVES:The primary aim of this study was to evaluate the histological adequacy of the liver tissue specimens obtained with a 20-gauge fine-needle biopsy needle and the secondary aim was to test the safety endoscopic ultrasound-guided liver biopsy with a 20-gauge fine-needle biopsy needle with the wet-heparinized su...

journal_title：European journal of gastroenterology & hepatology

authors： Sisman G,Barbur E,Saka D,Piyade B,Besli S,Boynukara C,Kirimlioglu H

更新日期：2020-11-01 00:00:00

abstract：AIM:Intrahepatic cholestasis of pregnancy (ICP) is associated with safe maternal outcomes but perinatal outcomes have been variable. We assessed clinical factors and impact of bile acid levels on maternal and neonatal outcomes in ICP. METHODS:Patients with ICP (defined as pruritus with serum bile acids ≥ 10 mmol/l) we...

journal_title：European journal of gastroenterology & hepatology

authors： Roy A,Premkumar M,Mishra S,Mehtani R,Suri V,Aggarwal N,Singh S,Dhiman RK

更新日期：2020-10-29 00:00:00

abstract：OBJECTIVE:Increasing attention is paid to measure patient's experience using specific patient-reported experience measures (PREMs) as tool to assess the overall quality of care provided. The European Society of Gastrointestinal Endoscopy and the United European Gastroenterology have recognized the measure of quality of...

journal_title：European journal of gastroenterology & hepatology

authors： Apadula L,Capurso G,Arcidiacono PG

更新日期：2020-10-29 00:00:00

abstract：OBJECTIVES:The hybrid allele of the carboxyl ester lipase gene (CEL-HYB1) is a genetic risk factor for chronic pancreatitis (CP) although the mechanism promoting disease development is largely unknown. Here, we aimed to clinically describe subjects carrying the CEL-HYB1 allele and to elucidate why the protein product i...

journal_title：European journal of gastroenterology & hepatology

authors： Tjora E,Gravdal A,Engjom T,Cnop M,Johansson BB,Dimcevski GG,Molven A,Fjeld K

更新日期：2020-10-16 00:00:00

abstract：:The question of when and how to drain a malignant biliary obstruction (MBO), both intrinsic or extrinsic, remains a controversial point among endoscopists. An important factor that influences the decision to drain an MBO or not is if the patient is a surgical candidate or not and, in the former case, if the patients m...

journal_title：European journal of gastroenterology & hepatology

authors： Mangiavillano B,Papanikolaou IS,Arvanitakis M,Auriemma F,Bianchetti M,Tarantino I,Traina M,Deviere J,Repici A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Massive amounts of patient data are captured daily in electronic medical records (EMR). Utilizing the power of such large data may help identify disease associations and generate hypotheses that can lead to a better understanding of disease associations and mechanisms. We aimed to comprehensively identify an...

journal_title：European journal of gastroenterology & hepatology

authors： Waljee AK,Noureldin M,Berinstein JA,Cohen-Mekelburg SA,Wallace BI,Cushing KC,Hanauer DA,Keeney-Bonthrone TP,Nallamothu B,Higgins PDR

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of thyroid function in the portal hypertension development and prognosis remains unclear. This study aimed to investigate the correlation between serum-free triiodothyronine (fT3) levels and the outcomes of cirrhotic portal hypertension. METHODS:A total of 385 cirrhotic patients with confi...

journal_title：European journal of gastroenterology & hepatology

authors： Huang X,Jiang S,Fan X,Jiang Y,Wu L,Li F,Wang J,Chen S

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Serrated lesions (sessile serrated adenomas/polyps and traditional serrated adenomas) owing to their subtle appearance and proximal location have a high miss rate. The objective of this study is to compare all the available endoscopic interventions for improving serrated adenoma detection rate (SADR) through ...

journal_title：European journal of gastroenterology & hepatology

authors： Aziz M,Fatima R,Lee-Smith W,Khuder S,Nawras A

更新日期：2020-10-01 00:00:00

abstract：:End-stage liver disease and its related complications exert a huge disease burden and reduce the survival rates of many patients. Albumin administration for patients with decompensated liver cirrhosis has been a controversial topic of discussion. The aim of this study is to investigate whether albumin reduces the mort...

journal_title：European journal of gastroenterology & hepatology

authors： Ashour AA,Atta MA,Sadek KW,Obaid KR,Ashour MA,Ashour A,Danjuma MI,Doi SA,ElZouki AN

更新日期：2020-09-23 00:00:00

abstract：:Recently, a controversial approach suggesting the early treatment of chronic infection with hepatitis B "e" antigen-positive patients with hepatitis B virus (HBV) infection, has been proposed. The objective of this study is to systematically review medical literature regarding treatment of HBV infection in adult chron...

journal_title：European journal of gastroenterology & hepatology

authors： Tovo CV,Ahlert M,Panke C,de Mattos ÂZ,de Mattos AA

更新日期：2020-09-15 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of ambulatory seton placement followed by superficial fistulotomy as treatment of perianal fistula. METHODS:Retrospective observational analysis of patients with cryptogenic perianal fistula aged 18-90 years, followed in a central hospital proctology consultation between 200...

journal_title：European journal of gastroenterology & hepatology

authors： Gamelas V,Simões G,Santos S,Loureiro R,Seves I,Costa Simões J,David Marques A,Bettencourt MJ

更新日期：2020-09-09 00:00:00

abstract：:Calprotectin is a promising diagnostic biomarker for spontaneous bacterial peritonitis (SBP) among cirrhotic patients, but published studies report a wide variation of its diagnostic accuracy. We systematically searched six databases for eligible studies (i.e., all original studies that reported ascitic calprotectin a...

journal_title：European journal of gastroenterology & hepatology

authors： Dibas M,Rajab AM,Zaghloul MS,Atiah MJ,Aljundi S,Amir A,Saquib N

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:An association of gastric cancer and precursor lesions with gastric xanthelasma has frequently been reported. However, the incidence of both gastric xanthelasma and gastric cancer precursor lesions increases with age. The aim of this study was to evaluate the frequency and characteristics of atrophic gastriti...

journal_title：European journal of gastroenterology & hepatology

authors： Sayar S,Ayranci G,Kürbüz K,Ak Ç,Tarikçi Kiliç E,Kahraman R,Atalay R,Öztürk O,Çalişkan Z,Adali G,Doganay L,Özdil K

更新日期：2020-09-01 00:00:00

abstract：:Fecal calprotectin has been widely studied in inflammatory bowel disease (IBD) under clinical and therapeutic settings. It showed a good correlation with clinical, endoscopic, and histologic findings. For these reasons, fecal calprotectin is currently one of the most useful tools in IBD care, both in diagnosis and in ...

journal_title：European journal of gastroenterology & hepatology

authors： Bertani L,Mumolo MG,Tapete G,Albano E,Baiano Svizzero G,Zanzi F,Ceccarelli L,Bellini M,Marchi S,Costa F

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Currently, monitoring hepatic venous pressure gradient (HVPG) have been proved to be the best predictor for the risk of variceal bleeding. We performed the study to evaluate the effect of endoscopic therapy + β-blocker vs. covered transjugular intrahepatic portosystemic shunt (TIPS) for the pre...

journal_title：European journal of gastroenterology & hepatology

authors： Guo H,Zhang F,Yin X,Zhang M,Xiao J,Wang Y,Zhang B,Zhang W,Zou X,Zhuge Y

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND AND AIMS:Current guidelines for chronic hepatitis B (CHB) patients are to undergo surveillance for hepatocellular carcinoma (HCC) with 6-month ultrasonography. We aimed to compare detection rates of very-early-stage HCC in two groups: group A, undergoing 6-month ultrasonography versus group B, undergoing 6-m...

journal_title：European journal of gastroenterology & hepatology

authors： Kim JH,Kang SH,Lee M,Choi HS,Jun BG,Kim TS,Choi DH,Suk KT,Kim MY,Kim YD,Cheon GJ,Baik SK,Kim DJ

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND AND AIMS:Proton pump inhibitors (PPIs) may reduce iron absorption and serum ferritin levels in patients with homeostatic iron regulator (HFE)-related hemochromatosis, reducing the need for frequent phlebotomies. Our study aimed to perform for the first time a meta-analysis of existing observational and rando...

journal_title：European journal of gastroenterology & hepatology

authors： Dirweesh A,Anugwom CM,Li Y,Vaughn BP,Lake J

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:This study was conducted to determine which type and dose of sedative drugs should be given to cirrhotic patients with compensation or decompensation during esophagogastroduodenoscopy (EGD) to prevent hepatic encephalopathy (HE) after sedation. METHODS:We reviewed the medical records of cirrhotic patients c...

journal_title：European journal of gastroenterology & hepatology

authors： Jeong J,Jung K,Seo KI,Yun BC,Han BH,Lee SU,Moon W

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Causes of small-bowel villous atrophy (VA) include coeliac disease (CD), its complications and other rare non-coeliac enteropathies. However, forms of VA of unknown aetiology may also exist. We defined them as idiopathic VA (IVA). To retrospectively classify the largest cohort of IVA patients and compare thei...

journal_title：European journal of gastroenterology & hepatology

authors： Schiepatti A,Sanders DS,Aziz I,De Silvestri A,Goodwin J,Key T,Quaye L,Giuffrida P,Vanoli A,Paulli M,Cross SS,Vergani P,Betti E,Maiorano G,Ellis R,Snowden JA,Di Sabatino A,Corazza GR,Biagi F

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:There is a controversy about the performance of blood tests for the diagnostic of metabolic liver disease in patients with type-2-diabetes in comparison with patients without type-2-diabetes. These indirect comparisons assumed that the gold-standard is binary, whereas fibrosis stages, steatosis and nonalcohol...

journal_title：European journal of gastroenterology & hepatology

authors： Poynard T,Peta V,Deckmyn O,Pais R,Ngo Y,Charlotte F,Ngo A,Munteanu M,Imbert-Bismut F,Monneret D,Housset C,Thabut D,Valla D,Boitard C,Castera L,Ratziu V,FLIP consortium, the FibroFrance Group, the EPIC-3 program and the QU

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Most patients with hepatocellular carcinoma are diagnosed at intermediate or advanced stages (BCLC B or C) and undergo palliative local treatments such as transarterial chemoembolization or selective internal radiation therapy, also called radioembolization. In terms of liver function and tumor extent, stages...

journal_title：European journal of gastroenterology & hepatology

authors： Jeliazkova P,Umgelter A,Braren R,Kaissis G,Mustafa M,Einwächter H

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:This work evaluates the burden and trends of hepatitis C virus (HCV)-associated hospitalisations in Spain before and after the implementation of the Strategic Plan for Tackling Hepatitis C in the National Health System in 2015. METHODS:HCV-related hospitalisation discharges from 2005 to 2017 were obtained...

journal_title：European journal of gastroenterology & hepatology

authors： Garrido-Estepa M,Latasa P,Flores-Herrera J,García Comas L

更新日期：2020-07-29 00:00:00

abstract：:Diagnosis of gastric intestinal metaplasia (GIM) under digital chromoendoscopy presents various markers. The diagnostic yield of each marker has shown variable results. A systematic review and meta-analysis were performed to evaluate the following markers: light blue crest (LBC), marginal turbid band (MTB), groove typ...

journal_title：European journal of gastroenterology & hepatology

authors： Wei N,Mulmi Shrestha S,Shi RH

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND/AIMS:The number of cases with coronavirus disease 2019 (COVID-19) has exceeded seven million worldwide. However, the data describing the global prevalence of liver injury associated with COVID-19 is lacking secondary to the novelty of this ongoing pandemic. Therefore, we conducted a meta-analysis to determin...

journal_title：European journal of gastroenterology & hepatology

authors： Wijarnpreecha K,Ungprasert P,Panjawatanan P,Harnois DM,Zaver HB,Ahmed A,Kim D

更新日期：2020-07-03 00:00:00

abstract：OBJECTIVES:Many individuals previously diagnosed with chronic hepatitis C virus (HCV) infection are likely to be lost to medical follow-up and, therefore, remain untreated despite new highly effective drug treatment, direct acting antivirals. We aim to identify and retrieve these chronic HCV-infected individuals to re-...

journal_title：European journal of gastroenterology & hepatology

authors： Heil J,Soufidi K,Stals F,Frantzen H,Robroek-Schaecken A,Bakker CM,van Nunen AB,Dukers-Muijrers NHTM,Hoebe CJPA

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The occurrence of hepatic encephalopathy is one of the main factors limiting the development and application of transjugular intrahepatic portosystemic shunt (TIPS). Our study aimed to verify the efficacy of the albumin-bilirubin score, an objective and simple scoring system, to predict post-TIPS he...

journal_title：European journal of gastroenterology & hepatology

authors： Lin X,Gao F,Wu X,Cai W,Chen X,Huang Z

更新日期：2020-06-11 00:00:00

abstract：INTRODUCTION:Excessive alcohol consumption has steadily risen to become the third leading cause of preventable death in the USA. One consequence of heavy alcohol use recently under considerable investigation is alcoholic hepatitis. Although many risk factors for developing alcoholic hepatitis have been documented, our ...

journal_title：European journal of gastroenterology & hepatology

authors： Al-Azzawi Y,Albo B,Fasullo M,Coukos J,Watts GJ,Tai R,Radcliffe D,Kroll-Desrosiers A,Devuni D,Szabo G

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:The data regarding the microbial spectrum in necrotizing pancreatitis and its impact on mortality is limited. Therefore, in this study, we aimed to investigate the agents identified in cultures and their impact on in-hospital and 1-year all-cause mortality. METHODS:Patients with necrotizing pancr...

journal_title：European journal of gastroenterology & hepatology

authors： Biberci Keskin E,Okay G,Muhiddin D,Sharif R,Taşlidere B,Şentürk H

更新日期：2020-06-01 00:00:00