Heparanase-2 and syndecan-1 in colon cancer: the ugly ducklings or the beautiful swans?

abstract：BACKGROUND:Mass screening programmes in Europe and in the USA have shown that a 15-18% decrease in mortality rate from colo-rectal cancer can be achieved with biannual testing. In a 10 year screening programme in the Isère region (France), we have noticed that the positivity percentage of Hemoccult II changes significa...

journal_title：European journal of gastroenterology & hepatology

authors： Faure H,Exbrayat C,Winckel P,Bolla M

更新日期：2003-10-01 00:00:00

abstract：AIM:To determine the prevalence of heterotopic gastric mucosa in the upper oesophagus (inlet patch) and the factors that may influence its finding. To study its macroscopic and microscopic characteristics and its relationship with symptoms and oesophago-gastroduodenal diseases. PATIENTS AND METHODS:The study was carri...

journal_title：European journal of gastroenterology & hepatology

authors： Maconi G,Pace F,Vago L,Carsana L,Bargiggia S,Bianchi Porro G

更新日期：2000-07-01 00:00:00

abstract：:This paper reviews the published data on novel drug treatments for inflammatory bowel disease. Steroids that are topically active or rapidly metabolized have a definite therapeutic role and have fewer long-term side-effects than other steroids. Methotrexate can promote remission in approximately 50% of patients, but i...

journal_title：European journal of gastroenterology & hepatology

authors： Debinski HS,Kamm MA

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical and prognostic value of the monoethyl glycine xylidide (MEGX) test in patients with primary biliary cirrhosis (PBC) in comparison with the Mayo score (Mayo). DESIGN:A prospective study. METHODS:MEGX determinations at enrolment were compared to the Mayo score as well as to convention...

journal_title：European journal of gastroenterology & hepatology

authors： Gindro T,Arrigoni A,Martinasso G,Rosina F,Perardi S,Cappello N,Benedetti P,Actis GC,Verme G,Rizzetto M

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To investigate a possible dose-effect relationship with two dosages of oral slow-release mesalazine in patients with quiescent ulcerative colitis. METHOD:One hundred and sixty-nine patients with ulcerative colitis in remission were treated with either 1.5 or 3.0 g/day mesalazine for 1 year or until relapse i...

journal_title：European journal of gastroenterology & hepatology

authors： Fockens P,Mulder CJ,Tytgat GN,Blok P,Ferwerda J,Meuwissen SG,Tuynman HA,Dekker W,Gasthuis K,van Hees PA

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Proton pump inhibitors (PPIs) may reduce iron absorption and serum ferritin levels in patients with homeostatic iron regulator (HFE)-related hemochromatosis, reducing the need for frequent phlebotomies. Our study aimed to perform for the first time a meta-analysis of existing observational and rando...

journal_title：European journal of gastroenterology & hepatology

authors： Dirweesh A,Anugwom CM,Li Y,Vaughn BP,Lake J

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVES:To characterize the antigen specificity of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) in inflammatory bowel disease (IBD). DESIGN:Analysis of the prevalence of circulating ANCAs in patients with ulcerative colitis and Crohn's disease, by both non-specific methods (immunofluorescence against ...

journal_title：European journal of gastroenterology & hepatology

authors： Kossa K,Coulthart A,Ives CT,Pusey CD,Hodgson HJ

更新日期：1995-08-01 00:00:00

abstract：:The question of when and how to drain a malignant biliary obstruction (MBO), both intrinsic or extrinsic, remains a controversial point among endoscopists. An important factor that influences the decision to drain an MBO or not is if the patient is a surgical candidate or not and, in the former case, if the patients m...

journal_title：European journal of gastroenterology & hepatology

authors： Mangiavillano B,Papanikolaou IS,Arvanitakis M,Auriemma F,Bianchetti M,Tarantino I,Traina M,Deviere J,Repici A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:α-Fetoprotein (AFP) and prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) are useful tumor markers for hepatocellular carcinoma (HCC). However, little is known about the clinical characteristics and prognosis of HCC with different levels of AFP and PIVKA-II. METHODS:Consecutive 1447...

journal_title：European journal of gastroenterology & hepatology

authors： Kang SH,Kim DY,Jeon SM,Ahn SH,Park JY,Kim SU,Kim JK,Lee KS,Chon CY,Han KH

更新日期：2012-07-01 00:00:00

abstract：:Genetic polymorphisms adjacent to IL28B have been previously associated with spontaneous clearance of hepatitis C virus (HCV) and a higher rate of sustained virological response to interferon-based treatment in HCV genotype 1-infected patients. A recent study has shown that patients with the CC genotype of the rs12979...

journal_title：European journal of gastroenterology & hepatology

authors： Chin JL,Nicholas RM,Russell J,Carr M,Connell J,Stewart S,McCormick PA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Currently, monitoring hepatic venous pressure gradient (HVPG) have been proved to be the best predictor for the risk of variceal bleeding. We performed the study to evaluate the effect of endoscopic therapy + β-blocker vs. covered transjugular intrahepatic portosystemic shunt (TIPS) for the pre...

journal_title：European journal of gastroenterology & hepatology

authors： Guo H,Zhang F,Yin X,Zhang M,Xiao J,Wang Y,Zhang B,Zhang W,Zou X,Zhuge Y

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:Physical activity affects the functioning of the gastrointestinal system through both local and systemic effects and may play an important role in the aetiology of gastroesophageal reflux disease, Barrett's oesophagus and oesophageal adenocarcinoma. We investigated, for the first time in a large prospective ...

journal_title：European journal of gastroenterology & hepatology

authors： Lam S,Alexandre L,Luben R,Hart AR

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:COX-2, the inducible isoenzyme, was found to be overexpressed in approximately 85% of colorectal adenocarcinomas, contributing to key steps in tumor development. COX-2 polymorphisms that might modify the levels of protein expression would be anticipated to have a substantial influence on disease phenotype. Th...

journal_title：European journal of gastroenterology & hepatology

authors： Pereira C,Pimentel-Nunes P,Brandão C,Moreira-Dias L,Medeiros R,Dinis-Ribeiro M

更新日期：2010-05-01 00:00:00

abstract：:Abdominal pain is a common symptom in individuals with cystic fibrosis (CF). As prognosis has improved, CF has changed from a pediatric disease to the current situation wherein most people with CF are adults. With improved survival, the spectrum of pathologies causing abdominal pain in CF has shifted. Despite this, th...

journal_title：European journal of gastroenterology & hepatology

authors： Nash EF,Ohri CM,Stephenson AL,Durie PR

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:It is known that duodenogastro-oesophageal reflux (DGOR) increases with worsening gastro-oesophageal reflux disease (GORD). It is unclear whether this is accompanied by increasing duodenogastric reflux (DGR). OBJECTIVE:To investigate the extent of DGR in a control group and 66 patients with GORD, using the ...

journal_title：European journal of gastroenterology & hepatology

authors： Marshall RE,Anggiansah A,Owen WA,Manifold DK,Owen WJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:As life expectancy rises worldwide and the prevalence of gallstones increases with age, the number of very elderly patients requiring treatment for gallstone diseases is increasing. The aim of this study was to compare the results of cholecystectomy in patients 80 years or older according to different clinic...

journal_title：European journal of gastroenterology & hepatology

authors： Lupinacci RM,Nadal LR,Rego RE,Dias AR,Marcari RS,Lupinacci RA,Farah JF

更新日期：2013-03-01 00:00:00

abstract：:Idiopathic fibrosing pancreatitis is an uncommon condition in children and adolescents of unknown aetiology. This syndrome has been reported in 36 cases so far. To our knowledge none of these cases was definitively associated with Crohn's disease. In this report we describe a young female patient who developed Crohn's...

journal_title：European journal of gastroenterology & hepatology

authors： Potamianos S,Koutroubakis IE,Chatzicostas C,Rolles K,Burroughs AK,Kouroumalis EA

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:The hepatitis B virus (HBV) and hepatitis C virus (HCV) infections may seriously affect survival rate. The median length of life in developed countries is increasing and the elderly may be considered as an epidemiologically distinct group due to higher whole-life risk of blood-borne viral infections. AIM:To...

journal_title：European journal of gastroenterology & hepatology

authors： Hartleb M,Gutkowski K,Zejda JE,Chudek J,Więcek A

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Radiolucent pancreatic lithiasis (RPL) has been identified as a different entity from calcified pancreatic lithiasis. The purpose of this study is to evaluate the frequency, characteristics and evolution of RPL. PATIENTS:Between 1983 and 1995, 278 consecutive patients who presented with pancreatic lithiasis ...

journal_title：European journal of gastroenterology & hepatology

authors： Barthet M,Daniel R,Bernard JP,Valantin V,Sahel J

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in inflammatory bowel disease (IBD) patients and the risk factors related to the infection and nonimmune status. METHODS:A retrospective study was carried out at two clinical centers. Th...

journal_title：European journal of gastroenterology & hepatology

authors： Chen D,Luo S,Ben Q,Lu L,Wan X,Wu J

更新日期：2017-05-01 00:00:00

abstract：:Fecal calprotectin has been widely studied in inflammatory bowel disease (IBD) under clinical and therapeutic settings. It showed a good correlation with clinical, endoscopic, and histologic findings. For these reasons, fecal calprotectin is currently one of the most useful tools in IBD care, both in diagnosis and in ...

journal_title：European journal of gastroenterology & hepatology

authors： Bertani L,Mumolo MG,Tapete G,Albano E,Baiano Svizzero G,Zanzi F,Ceccarelli L,Bellini M,Marchi S,Costa F

更新日期：2020-09-01 00:00:00

abstract：:A growing amount of evidence indicates that the intestinal flora plays a pathogenic role in inflammatory bowel disease (IBD): hence, the use of anti-bacterial agents as ancillary treatment in patients with ulcerative colitis, or Crohn's disease. While the results with anti-tubercular agents remain inconclusive, antibi...

journal_title：European journal of gastroenterology & hepatology

authors： Guslandi M

更新日期：2005-02-01 00:00:00

abstract：:Adult Still's disease is a well-characterized rheumatic disorder of unknown origin, which may affect multiple organs and may have a fatal course. However, liver failure has rarely been described in adult Still's disease. We present the case of a 25-year-old woman who was admitted with acute liver failure 2 years after...

journal_title：European journal of gastroenterology & hepatology

authors： Ott SJ,Baron A,Berghaus T,Lamerz R,Beuers U

更新日期：2003-01-01 00:00:00

abstract：:Concomitant functional dyspepsia (FD) and psychosocial stressors have been reported; however, the association between FD and depression remains controversial and no quantitative meta-analysis exists. Published articles were identified through a comprehensive review of PubMed, Embase, and Web of Science from inception ...

journal_title：European journal of gastroenterology & hepatology

authors： Lin S,Gao T,Sun C,Jia M,Liu C,Ma A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIMS:There is a continuing demand for the provision of open-access endoscopy services. While open-access gastroscopy is now a well-established practice in most hospitals, open-access flexible sigmoidoscopy (OAS) is not yet available to the same extent. We present our early experience with OAS, a new serv...

journal_title：European journal of gastroenterology & hepatology

authors： Verma S,Giaffer MH

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:A wide range in values of liver stiffness measurement (LSM) is observed among cirrhotic patients. These variations reflect the extent of fibrosis and might influence the risk of hepatocellular carcinoma (HCC) occurrence. METHODS:We compared LSM in 66 Child-Pugh A patients with HCC and alcoholic (n=23) or HCV...

journal_title：European journal of gastroenterology & hepatology

authors： Nahon P,Kettaneh A,Lemoine M,Seror O,Barget N,Trinchet JC,Beaugrand M,Ganne-Carrié N

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Bosnia and Herzegovina (B&H) is one of the Eastern European countries that lacks data on the epidemiology of ulcerative colitis (UC). AIMS:We aimed to assess the epidemiological and clinical characteristics of UC in Tuzla Canton of B&H during a 12-year period (1995-2006). PATIENTS AND METHODS:We retrospect...

journal_title：European journal of gastroenterology & hepatology

authors： Salkic NN,Pavlovic-Calic N,Gegic A,Jovanovic P,Basic M

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate if single nucleotide polymorphisms (SNPs) in a series of inflammatory genes were associated with the development of the most common pathologies thought to precede gastric cancer development namely; Helicobacter pylori (H. pylori)-associated gastritis and intestinal metaplasia....

journal_title：European journal of gastroenterology & hepatology

authors： Murphy G,Thornton J,McManus R,Swan N,Ryan B,Hughes DJ,O'Morain CA,O'Sullivan M

更新日期：2009-06-01 00:00:00

abstract：:Chronic hepatitis B continues to be a major global health burden. It accounts for a substantial impact on health care resources and finances in many parts of the world including Europe. Natural history and disease spectrum are varied, depending on when and how the infection is acquired. The chronic infective state inc...

journal_title：European journal of gastroenterology & hepatology

authors： Massoumi H,Martin P,Tan HH

更新日期：2011-08-01 00:00:00

abstract：:Interferon therapy is the cornerstone of chronic hepatitis C treatment. Side effects of interferon include possible triggering or exacerbation of immune diseases in consequence of immunomodulatory effects. We describe the unique case, in which pyoderma gangrenosum and exacerbation of psoriasis were developed 8 weeks a...

journal_title：European journal of gastroenterology & hepatology

authors： Yurci A,Guven K,Torun E,Gursoy S,Baskol M,Akgun H,Ozbakir O,Yucesoy M

更新日期：2007-09-01 00:00:00