Novel drug therapies in inflammatory bowel disease.

abstract：OBJECTIVE:To investigate a possible dose-effect relationship with two dosages of oral slow-release mesalazine in patients with quiescent ulcerative colitis. METHOD:One hundred and sixty-nine patients with ulcerative colitis in remission were treated with either 1.5 or 3.0 g/day mesalazine for 1 year or until relapse i...

journal_title：European journal of gastroenterology & hepatology

authors： Fockens P,Mulder CJ,Tytgat GN,Blok P,Ferwerda J,Meuwissen SG,Tuynman HA,Dekker W,Gasthuis K,van Hees PA

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of thyroid function in the portal hypertension development and prognosis remains unclear. This study aimed to investigate the correlation between serum-free triiodothyronine (fT3) levels and the outcomes of cirrhotic portal hypertension. METHODS:A total of 385 cirrhotic patients with confi...

journal_title：European journal of gastroenterology & hepatology

authors： Huang X,Jiang S,Fan X,Jiang Y,Wu L,Li F,Wang J,Chen S

更新日期：2020-10-01 00:00:00

abstract：:Interferon therapy is the cornerstone of chronic hepatitis C treatment. Side effects of interferon include possible triggering or exacerbation of immune diseases in consequence of immunomodulatory effects. We describe the unique case, in which pyoderma gangrenosum and exacerbation of psoriasis were developed 8 weeks a...

journal_title：European journal of gastroenterology & hepatology

authors： Yurci A,Guven K,Torun E,Gursoy S,Baskol M,Akgun H,Ozbakir O,Yucesoy M

更新日期：2007-09-01 00:00:00

abstract：:Encephalopathy is a significant complication of transjugular intrahepatic portosystemic stent-shunt (TIPSS). The majority respond to medical treatment but a proportion prove recalcitrant to conservative measures and eventually require some modulation of shunt blood flow in order to ameliorate their symptoms. This is p...

journal_title：European journal of gastroenterology & hepatology

authors： Clarke G,Patel R,Tsao S,Blanshard K

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Radiolucent pancreatic lithiasis (RPL) has been identified as a different entity from calcified pancreatic lithiasis. The purpose of this study is to evaluate the frequency, characteristics and evolution of RPL. PATIENTS:Between 1983 and 1995, 278 consecutive patients who presented with pancreatic lithiasis ...

journal_title：European journal of gastroenterology & hepatology

authors： Barthet M,Daniel R,Bernard JP,Valantin V,Sahel J

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in inflammatory bowel disease (IBD) patients and the risk factors related to the infection and nonimmune status. METHODS:A retrospective study was carried out at two clinical centers. Th...

journal_title：European journal of gastroenterology & hepatology

authors： Chen D,Luo S,Ben Q,Lu L,Wan X,Wu J

更新日期：2017-05-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic inflammatory process, the aetiology of which is complex and probably multi-factorial. Nutrition has been proposed to be an important aetiological factor for IBD. The present review critically examines the relationship between components of the diet (such as sugar, fat, fib...

journal_title：European journal of gastroenterology & hepatology

authors： Cashman KD,Shanahan F

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Perihilar cholangiocarcinoma (PHCC) is a rare tumor with a poor prognosis. Outcomes may be optimized by centralization. Recent trends suggest further improvement by localization to transplant centers. This study examines outcomes from the management of PHCC in a nontransplant hepatopancreatobiliary center. ...

journal_title：European journal of gastroenterology & hepatology

authors： Jegatheeswaran S,Sheen AJ,Siriwardena AK

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the potential usefulness of contrast-enhanced power Doppler ultrasound in the detection and follow-up of local complications (phlegmon and abscess) in Crohn's disease. METHODS:With this aim, 28 patients with suspected abdominal inflammatory mass were examined with po...

journal_title：European journal of gastroenterology & hepatology

authors： Esteban JM,Aleixandre A,Hurtado MJ,Maldonado L,Mora FJ,Nogués E

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:Data on SARS-CoV-2 disease (COVID-19) in adult coeliac disease (CD) are lacking. The aim of the present study is to evaluate the epidemiology and clinical features of COVID-19 in adult coeliac patients regularly followed-up at our centre since January 2015. METHODS:Data about general health status and clini...

journal_title：European journal of gastroenterology & hepatology

authors： Schiepatti A,Alimenti E,Maimaris S,Nicolardi ML,Manzella La Barbera F,Baiardi P,Biagi F

更新日期：2021-01-04 00:00:00

abstract：OBJECTIVE:To evaluate the clinical presentation, biochemical (ascites and serum) and laparoscopic findings, and to assess the efficacy of triple antituberculous therapy without rifampicin for 6 months in patients with tuberculous peritonitis. METHODS:Twenty-six tuberculous peritonitis patients (11 male, 15 female) wit...

journal_title：European journal of gastroenterology & hepatology

authors： Demir K,Okten A,Kaymakoglu S,Dincer D,Besisik F,Cevikbas U,Ozdil S,Bostas G,Mungan Z,Cakaloglu Y

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Symptoms due to slowing of gastrointestinal motility constitute an important problem in most patients with primary hypothyroidism. The purpose of this study was to calculate gastric emptying time in patients with primary hypothyroidism using a radioisotopic method. PATIENTS AND METHODS:Fiftee...

journal_title：European journal of gastroenterology & hepatology

authors： Kahraman H,Kaya N,Demirçali A,Bernay I,Tanyeri F

更新日期：1997-09-01 00:00:00

abstract：:We report on four cases displaying the wide range of aetiological risk factors (presence or absence of family history of dyslipidaemia and cryptogenic cirrhosis, from subnormal body mass index through morbid obesity, from absent through hepatotoxic alcohol consumption), laboratory test results (from subnormal through ...

journal_title：European journal of gastroenterology & hepatology

authors： Lonardo A,Bagni A,Tarugi P,Loria P

更新日期：2004-10-01 00:00:00

abstract：:The first-line management of the later complications of severe acute pancreatitis has moved increasingly towards a non-operative approach. Asymptomatic pseudocysts may be safely observed while awaiting spontaneous resolution. Symptomatic, enlarging or complicated pseudocysts, particularly those with an immature wall, ...

journal_title：European journal of gastroenterology & hepatology

authors： Wilson C

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:To investigate gallbladder function by use of cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage. DESIGN:A cholescintigraphy was performed in 40 patients with acute cholecystitis before and after the performance of percutaneous gallbladder drainage. Duri...

journal_title：European journal of gastroenterology & hepatology

authors： Borly L,Stage JG,Grønvall S,Højgaard L

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Several classifications of mucosal morphology have been proposed in Barrett oesophagus using narrow-band imaging (NBI). We evaluated a simplified classification in which only the regularity of mucosal and vascular patterns were evaluated. AIM:To assess the inter and intraobserver agreement and the correlati...

journal_title：European journal of gastroenterology & hepatology

authors： Alvarez Herrero L,Curvers WL,Bansal A,Wani S,Kara M,Schenk E,Schoon EJ,Lynch CR,Rastogi A,Pondugula K,Weusten B,Sharma P,Bergman JJ

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:The prognostic value of p53 protein accumulation in colonic adenomas is still controversial. The aim of the present study was to determine whether the evaluation of p53 protein accumulation in newly diagnosed colonic adenomas could predict the development of metachronous adenomas. DESIGN/METHODS:Fifty-five ...

journal_title：European journal of gastroenterology & hepatology

authors： Triantafyllou K,Paspatis GA,Zizi A,Papatheodoridis GV,Tzouvala M,Chlouverakis GJ,Elemenoglou I,Karamanolis DG

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:To characterize the antigen specificity of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) in inflammatory bowel disease (IBD). DESIGN:Analysis of the prevalence of circulating ANCAs in patients with ulcerative colitis and Crohn's disease, by both non-specific methods (immunofluorescence against ...

journal_title：European journal of gastroenterology & hepatology

authors： Kossa K,Coulthart A,Ives CT,Pusey CD,Hodgson HJ

更新日期：1995-08-01 00:00:00

abstract：:Hereditary hyperferritinaemia-cataract syndrome (HHCS) is a relatively rare disorder with an autosomal dominant trait. It can be caused by various mutations within the iron responsive element (IRE) of the L-ferritin gene. These mutations result in an increased translation of L-ferritin mRNA and consequently the accumu...

journal_title：European journal of gastroenterology & hepatology

authors： Ferrante M,Geubel AP,Fevery J,Marogy G,Horsmans Y,Nevens F

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Varices are a late complication in primary biliary cirrhosis (PBC). However, patients without clinical jaundice do bleed from varices; whether their prognosis differs is unknown. AIM:Evaluate PBC patients, particularly those with bilirubin

journal_title：European journal of gastroenterology & hepatology

authors： Vlachogiannakos J,Carpenter J,Goulis J,Triantos C,Patch D,Burroughs AK

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The detection of bacterial DNA in serum and ascitic fluid from patients with cirrhosis and ascites is interpreted as molecular evidence of intestinal bacterial translocation and considered sufficient to activate the cellular immune response. In vitro studies on ascitic fluid culture have shown a close relati...

journal_title：European journal of gastroenterology & hepatology

authors： Francés R,Rodríguez E,Muñoz C,Zapater P,De la ML,Ndongo M,Pérez-Mateo M,Such J

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Spontaneous bacterial peritonitis (SBP) is one of the potentially life-threatening complications in ascitic cirrhotic patients with a mortality rate ranging between 30 and 50%. The improved survival might be explained by a more rapid diagnosis and treatment. The aim of our study was to assess the utility of t...

journal_title：European journal of gastroenterology & hepatology

authors： Thévenot T,Cadranel JF,Nguyen-Khac E,Tilmant L,Tiry C,Welty S,Merzoug N

更新日期：2004-06-01 00:00:00

abstract：:Prophylaxis with norfloxacin has been shown to be effective in preventing spontaneous bacterial peritonitis (SBP) in liver cirrhosis. This therapy is associated with the appearance of quinolone-resistant Escherichia coli. However, only four cases of SBP caused by quinolone-resistant E. coli have been reported so far. ...

journal_title：European journal of gastroenterology & hepatology

authors： Cereto F,Genescà J,Smithson A,González A,Moreno G,del Valle Ortiz O,Esteban R,Guardia J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are usually prescribed to patients undergoing dual antiplatelet therapy to decrease the risk of gastrointestinal bleeding. Recent studies have raised concerns that PPIs could reduce clopidogrel's efficacy by competitive inhibition of cytochrome P450 2C19 isoenzyme. All PPIs are ...

journal_title：European journal of gastroenterology & hepatology

authors： Fontes-Carvalho R,Albuquerque A,Araújo C,Pimentel-Nunes P,Ribeiro VG

更新日期：2011-05-01 00:00:00

abstract：:Gilbert's syndrome is a common inherited disorder, in which genetic defects in uridine diphosphate-glucuronosyltransferase 1A1 lead to deficient glucuronidation of bilirubin and hence hyperbilirubinaemia. Although usually considered asymptomatic, Gilbert's syndrome can be associated with gastrointestinal and psychiatr...

journal_title：European journal of gastroenterology & hepatology

authors： Lee P,Jones G,Seibel MJ

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIM:There are millions of chronic hepatitis C (CHC) virus-infected patients who have been treated with a combination therapy (interferon and ribavirin) and have achieved a virological response (SVR) worldwide. The aim of this study is to evaluate the risk factors for de-novo diabetes mellitus in CHC pati...

journal_title：European journal of gastroenterology & hepatology

authors： Mousa N,Abdel-Razik A,Farag R,Shabana W,Elgamal A,El-Wakeel N,Elzehery R,Elkashef W,Eldars W

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The diagnostic and prognostic value of critical flicker frequency (CFF) analysis for assessment of severity and dynamics of hepatic encephalopathy (HE) was studied before and after implantation of a transjugular intrahepatic portosystemic shunt (TIPS). BASIC METHODS:Sixty-three cirrhotic patients were retro...

journal_title：European journal of gastroenterology & hepatology

authors： Kircheis G,Bode JG,Hilger N,Kramer T,Schnitzler A,Häussinger D

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:The early identification of factors contributing to the successful treatment of hepatitis C infection is important for researchers and clinicians. Studies carried out on the role of an ultrarapid viral response (URVR) for the prediction of a sustained viral response (SVR) have shown its high positive predict...

journal_title：European journal of gastroenterology & hepatology

authors： Karchava M,Sharvadze L,Chkhartishvili N,Nelson K,Gochitashivli N,Gatserelia L,Dvali N,Dolmazashvili E,Dzigua L,Badridze N,Zhamutashvili M,Tsertsvadze T

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus can occur after acute pancreatitis (AP), but there are currently no tools for evaluating the risk of developing diabetes after an attack of AP. The aim of the study was to develop a nomogram for prediction of new-onset diabetes mellitus after the first attack of AP. PATIENTS AND METHODS:We...

journal_title：European journal of gastroenterology & hepatology

authors： Ma JH,Yuan YJ,Lin SH,Pan JY

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To determine the efficacy of a three times daily (t.i.d.) versus a twice daily (b.i.d.) regimen of combination amoxycillin and metronidazole and famotidine in the eradication of Helicobacter pylori and the influence of metronidazole resistance on the outcome of treatment. PATIENTS:Patients selected had uneq...

journal_title：European journal of gastroenterology & hepatology

authors： Goh KL,Parasakthi N,Chuah SY,Toetsch M

更新日期：1997-11-01 00:00:00