Abstract:
BACKGROUND AND AIMS:The role of thyroid function in the portal hypertension development and prognosis remains unclear. This study aimed to investigate the correlation between serum-free triiodothyronine (fT3) levels and the outcomes of cirrhotic portal hypertension. METHODS:A total of 385 cirrhotic patients with confirmed portal hypertension underwent computed tomography angiography and thyroid function test at a tertiary care referral center from January 2009 to December 2017. The patients were assigned to the low-fT3 (n = 98) and normal-fT3 groups (n = 287). RESULTS:Child-Pugh (8.88 ± 0.22 vs. 7.09 ± 0.12, P < 0.001) and model for end-stage liver disease (MELD) scores (14.75 ± 0.57 vs. 10.59 ± 0.23, P < 0.001) significantly increased in the low-fT3 group. The hemoglobin level correlated with fT3 (R = 0.299, P < 0.0001) and fT4 (R = 0.310, P < 0.0001), while only fT3 significantly correlated with the albumin level (R = 0.537, P < 0.001). The Kaplan-Meier analysis indicated that the two-year survival rate was 74.51% in the low-fT3 group vs. 94.25% in the normal-fT3 group (P < 0.0001). The Cox regression analysis demonstrated that the serum level of fT3 [hazard ratio: 0.478; 95% confidence interval (CI) 0.391-0.758; P = 0.002] and prothrombin time (hazard ratio: 2.247; 95% CI: 1.316-3.838; P = 0.003) were independent prognostic factors in cirrhotic patients. CONCLUSION:The low fT3 level was associated with poor prognosis and the progression of cirrhotic portal hypertension.
journal_name
Eur J Gastroenterol Hepatoljournal_title
European journal of gastroenterology & hepatologyauthors
Huang X,Jiang S,Fan X,Jiang Y,Wu L,Li F,Wang J,Chen Sdoi
10.1097/MEG.0000000000001658subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1358-1363issue
10eissn
0954-691Xissn
1473-5687journal_volume
32pub_type
杂志文章abstract:OBJECTIVE:To investigate gallbladder function by use of cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage. DESIGN:A cholescintigraphy was performed in 40 patients with acute cholecystitis before and after the performance of percutaneous gallbladder drainage. Duri...
journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/00042737-199511000-00013
更新日期:1995-11-01 00:00:00
abstract::This review presents the data that are now available concerning the effects of dietary polyamines at either postnatal or adult stages in non-neoplastic growth and disease. Polyamines provided by food have a potential role in growth and development of the digestive system in neonatal mammals (and fishes). In humans, th...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
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abstract:BACKGROUND:Initial venesection therapy in dysmetabolic iron overload syndrome (DIOS) was shown to improve insulin resistance. However, no data are available on the long-term outcome of iron store, thus questioning the relevance of maintenance therapy. AIM:The aim of the study was to describe the long-term evolution of...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0000000000000058
更新日期:2014-04-01 00:00:00
abstract::A 46-year-old woman was admitted to our department with symptoms of nausea, anorexia and asthenia. Serum alanine aminotransferase and aspartate aminotransferase levels were increased; all serological tests for viral hepatitis and autoimmune disorders were negative. She had taken Lycopodium similiaplex solution as seda...
journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/MEG.0b013e3282f1623d
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abstract:BACKGROUND AND AIM:Body composition has emerged as a prognostic factor for end-stage liver disease. We therefore investigated muscle mass, body fat and other clinical-pathological variables as predictors of posttransplant survival. METHODS:A total of 368 patients, who underwent orthotopic liver transplantation (OLT) a...
journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/MEG.0000000000001234
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journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/00042737-200509000-00018
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abstract:BACKGROUND:Variceal bleeding is a medical emergency with 20% mortality at 6 weeks. The role of vasoactive agents in achieving hemostasis and preventing rebleeding has been well documented. The optimal duration of these agents has not been well established. There are no previous studies yielding the exact duration of oc...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,随机对照试验
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0b013e32834dfdfa
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abstract:BACKGROUND:Studying factors associated with positive gastroscopies in dyspeptic patients can help limit and rationalize waiting lists for endoscopies. Dyspepsia guidelines have a controversial role because their main purpose is to provide specifications on efficient global management of primary care patients. AIM:To a...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/01.meg.0000216942.42306.d5
更新日期:2007-07-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-200306000-00015
更新日期:2003-06-01 00:00:00
abstract::We report the case of a 66-year-old man with chronic hepatitis C and a slowly growing left chest wall mass. Two years after the patient first noticed the mass, it was resected. A diagnosis of hepatocellular carcinoma (HCC) was established. The liver was studied by ultrasound, computed tomography (CT), magnetic resonan...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-200107000-00018
更新日期:2001-07-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/00042737-200206000-00011
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abstract:BACKGROUND AND AIMS:The literature on colorectal cancer (CRC) screening and ethnic diversity is dominated by studies from the USA. There are no such published data from the UK bowel cancer screening programme (BCSP) population. The Wolverhampton Bowel Cancer Screening Centre serves a population of 900,000 in the Black ...
journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0000000000000443
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:The high vascularity of hepatocellular carcinoma (HCC) seems to be a potential therapeutic target. We evaluated the efficacy, toxicity, and histologic response to thalidomide in advanced HCC in a single center phase I/II pilot trial. METHODS:Between September 2000 and August 2004 patients with HCC uneligibl...
journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/MEG.0b013e3283036740
更新日期:2008-10-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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doi:10.1097/MEG.0000000000000468
更新日期:2015-12-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
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更新日期:1999-04-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 评论,杂志文章
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更新日期:2003-07-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,多中心研究
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更新日期:2012-07-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
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journal_title:European journal of gastroenterology & hepatology
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更新日期:2013-09-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章,评审
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更新日期:2017-02-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/01.meg.0000216928.91618.9a
更新日期:2006-07-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0000000000000072
更新日期:2014-05-01 00:00:00
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journal_title:European journal of gastroenterology & hepatology
pub_type: 杂志文章
doi:10.1097/MEG.0b013e3282f5dda4
更新日期:2008-09-01 00:00:00