Antibiotics for inflammatory bowel disease: do they work?

abstract：OBJECTIVE:To investigate a possible dose-effect relationship with two dosages of oral slow-release mesalazine in patients with quiescent ulcerative colitis. METHOD:One hundred and sixty-nine patients with ulcerative colitis in remission were treated with either 1.5 or 3.0 g/day mesalazine for 1 year or until relapse i...

journal_title：European journal of gastroenterology & hepatology

authors： Fockens P,Mulder CJ,Tytgat GN,Blok P,Ferwerda J,Meuwissen SG,Tuynman HA,Dekker W,Gasthuis K,van Hees PA

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy of lansoprazole 30 mg given in the morning compared with high-dose ranitidine 300 mg twice daily in the treatment of patients with oesophageal strictures. DESIGN:A multicentre, outpatient, double-blind, parallel group, prospectively randomized clinical trial. PATIENTS:One hundred a...

journal_title：European journal of gastroenterology & hepatology

authors： Swarbrick ET,Gough AL,Foster CS,Christian J,Garrett AD,Langworthy CH

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor (EGF) and transforming growth factor (TGF)-alpha protect the gastrointestinal mucosa against injury. In response to mucosal injury TGF-alpha, but not EGF, is locally increasingly expressed in the mucosa of the rat colon and stomach 4-8 h after injury. The aim of our present study was ...

journal_title：European journal of gastroenterology & hepatology

authors： Hoffmann P,Dignass AU,Zeeh JM,Mazurkiewicz J,Holtmann G,Gerken G

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical presentation, biochemical (ascites and serum) and laparoscopic findings, and to assess the efficacy of triple antituberculous therapy without rifampicin for 6 months in patients with tuberculous peritonitis. METHODS:Twenty-six tuberculous peritonitis patients (11 male, 15 female) wit...

journal_title：European journal of gastroenterology & hepatology

authors： Demir K,Okten A,Kaymakoglu S,Dincer D,Besisik F,Cevikbas U,Ozdil S,Bostas G,Mungan Z,Cakaloglu Y

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Barrett's epithelium is a premalignant condition in which endoscopic surveillance is recommended but remains contentious. AIM:To audit our Barrett's epithelium surveillance database and to calculate the incidence and natural history of dysplasia and cancer in this cohort. METHODS:A retrospective analysis o...

journal_title：European journal of gastroenterology & hepatology

authors： Basu KK,Pick B,de Caestecker JS

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic variceal band ligation (EVBL) aims to eradicate high-risk oesophageal varices. There is a small risk of precipitating bleeding from EVBL-induced oesophageal ulceration, which is associated with significant mortality. We explore the risk factors and outcome of EVBL-induced ulcer bleeding. ...

journal_title：European journal of gastroenterology & hepatology

authors： Sinclair M,Vaughan R,Angus PW,Gow PJ,Parker F,Hey P,Efthymiou M

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:For palliation of extrahepatic bile duct obstruction, self-expandable metal stents (SEMS) are superior to plastic stents in terms of stent patency and occurrence of stent dysfunction. We assessed health-related quality of life (HRQoL) after stent placement to investigate whether this also results in a differe...

journal_title：European journal of gastroenterology & hepatology

authors： Walter D,van Boeckel PG,Groenen MJ,Weusten BL,Witteman BJ,Tan G,Brink MA,Nicolai J,Tan AC,Alderliesten J,Venneman NG,Laleman W,Jansen JM,Bodelier A,Wolters FL,van der Waaij LA,Breumelhof R,Peters FT,Scheffer RC,Stey

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:The model of end-stage liver disease (MELD) score has been shown to predict 3-month prognosis following transjugular intrahepatic portosystemic stent shunt (TIPS) in liver cirrhosis; however, that score was derived from a mixed cohort, including patients with refractory ascites and variceal bleeding. This study...

journal_title：European journal of gastroenterology & hepatology

authors： Pitton MB,Zimmermann T,Mildenberger P,Weinmann A,Kloeckner R,Düber C,Mittler J,Hoppe-Lotichius M,Otto G

更新日期：2020-11-20 00:00:00

abstract：AIMS:The purpose of this study was to investigate the expression level of KAI-1 in gastric carcinomas and compare with the clinicopathological characteristics. METHODS:KAI-1 expressions were detected with immunohistochemical methods in 257 patients with gastric carcinomas. RESULTS:KAI-1 was highly expressed in normal...

journal_title：European journal of gastroenterology & hepatology

authors： Ilhan O,Celik SY,Han U,Onal B

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:A wide range in values of liver stiffness measurement (LSM) is observed among cirrhotic patients. These variations reflect the extent of fibrosis and might influence the risk of hepatocellular carcinoma (HCC) occurrence. METHODS:We compared LSM in 66 Child-Pugh A patients with HCC and alcoholic (n=23) or HCV...

journal_title：European journal of gastroenterology & hepatology

authors： Nahon P,Kettaneh A,Lemoine M,Seror O,Barget N,Trinchet JC,Beaugrand M,Ganne-Carrié N

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Minimal hepatic encephalopathy (MHE) impairs daily functioning and health-related quality of life (HRQoL). The modalities of treatment of MHE have not been adequately studied. AIMS:To compare lactulose, probiotics, and L-ornithine L-aspartate (LOLA) in treatment of MHE and effect on HRQoL by Sickness Impact...

journal_title：European journal of gastroenterology & hepatology

authors： Mittal VV,Sharma BC,Sharma P,Sarin SK

更新日期：2011-08-01 00:00:00

abstract：:Improved technology and new clinical methods have expanded the possibilities of using ultrasound in the daily routine of gastroenterology. Gastrointestinal ultrasonography can, in principle, be applied in two different ways in patient management. It can be used as one imaging modality among others, for which the clini...

journal_title：European journal of gastroenterology & hepatology

authors： Gilja OH,Hausken T,Ødegaard S,Berstad A

更新日期：2005-03-01 00:00:00

abstract：:Over the last decade, major advancements have been made in our understanding of both the beneficial and detrimental role that microorganisms play in our innate functioning. Research into the intestinal microbiota has moved from the laboratory into our medical clinics and is being put forth as an effective therapy for ...

journal_title：European journal of gastroenterology & hepatology

authors： Tamilarasan AG,Krishnananthan T

更新日期：2020-11-10 00:00:00

abstract：:Here we report two cases of inverted hyperplastic polyps of the colon. The first patient showed three inverted hyperplastic polyps in the ascending colon, one of which was associated with adenoma. We immunostained this adenoma-associated polyp using anti-beta-catenin antibody and found accumulation of beta-catenin in ...

journal_title：European journal of gastroenterology & hepatology

authors： Kuribayashi K,Ishii T,Ishidate T,Ban N,Hirata Y,Hashida H,Saito K,Iwashiro N,Ohara M,Ishizaka M,Azumad M,Hayashi T,Takayama T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Liver steatosis (LS) and chronic infection with hepatitis B virus (HBV) are two common causes of chronic liver disease in Iran. LS is also a common histopathological feature of chronic hepatitis B (CHB). Association of chronic HBV infection and LS has not been extensively studied. AIM:We investigated the pr...

journal_title：European journal of gastroenterology & hepatology

authors： Minakari M,Molaei M,Shalmani HM,Mohammad Alizadeh AH,Jazi AH,Naderi N,Shavakhi A,Mashayekhi R,Zali MR

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Cells infected with the hepatitis B or C virus can be eliminated by an immune response mediated by cytotoxic T cells. Recently, the Fas Ligand has been detected on the surface of cytotoxic T cells, and is thought to induce cells to apoptosis by adhering to the Fas antigen. METHODS:To evaluate the role of th...

journal_title：European journal of gastroenterology & hepatology

authors： Oksuz M,Akkiz H,Isiksal YF,Seydaoglu G,Serin M,Kayaselcuk F,Abayli B,Tuncer I

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although the number of ulcerative colitis patients has increased rapidly in Japan, few reports have been published regarding their clinical aspects. We investigated the clinical characteristics and chronological change of ulcerative colitis in Japanese patients. METHODS:Patients diagnosed with ulcerative co...

journal_title：European journal of gastroenterology & hepatology

authors： Fujimoto T,Kato J,Nasu J,Kuriyama M,Okada H,Yamamoto H,Mizuno M,Shiratori Y,Japan West Ulcerative Colitis (JWUC) Study Group.

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The role of heterozygosity for alpha-1 antitrypsin (A1AT) alleles in patients with chronic hepatitis C virus (HCV) is unclear. There is limited evidence to suggest that there is an increased prevalence of heterozygous A1AT carriers in HCV, but it is unclear how this affects treatment success. AIM:To investi...

journal_title：European journal of gastroenterology & hepatology

authors： Kok KF,van Soest H,van Herwaarden AE,van Oijen MG,Boland GJ,Halangk J,Berg T,de Vries RA,Drenth JP

更新日期：2010-07-01 00:00:00

abstract：:We studied the role of brain electrical activity mapping (BEAM) in the assessment of neuropsychiatric disturbances in 48 cirrhotic patients without clinical evidence of hepatic encephalopathy (no HE, n = 19), with subclinical HE (grade 0, denoting pathological psychometric tests, n = 13) and mild-to-moderate HE (grade...

journal_title：European journal of gastroenterology & hepatology

authors： Kullmann F,Hollerbach S,Lock G,Holstege A,Dierks T,Schölmerich J

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Complementary and alternative medicine (CAM) seems to be frequently used among patients with inflammatory bowel disease (IBD). We aimed to determine the prevalence and indicators of CAM use in Austrian IBD patients. METHODS:In a multicentre cross-sectional study, adult patients with IBD attending 18 Austrian...

journal_title：European journal of gastroenterology & hepatology

authors： Gröchenig HP,Waldhör T,Haas T,Wenzl H,Steiner P,Koch R,Feichtenschlager T,Eckhardt G,Mayer A,Kirchgatterer A,Ludwiczek O,Platzer R,Papay P,Gartner J,Fuchssteiner H,Miehsler W,Peters PG,Reicht G,Kutschera M,Dejaco C

更新日期：2019-10-01 00:00:00

abstract：:A 46-year-old woman was admitted to our department with symptoms of nausea, anorexia and asthenia. Serum alanine aminotransferase and aspartate aminotransferase levels were increased; all serological tests for viral hepatitis and autoimmune disorders were negative. She had taken Lycopodium similiaplex solution as seda...

journal_title：European journal of gastroenterology & hepatology

authors： Conti E,De Checchi G,Mencarelli R,Pinato S,Rovere P

更新日期：2008-05-01 00:00:00

abstract：:Esophageal variceal bleeding can be serious or life threatening. Drug-induced thrombocytopenia can further complicate such bleeding episodes. Thrombocytopenia because of sandostatin has been reported in the literature only once previously. We describe a case of sandostatin-induced reversible thrombocytopenia with a po...

journal_title：European journal of gastroenterology & hepatology

authors： Chisholm S,Gummadi B,Vega KJ,House J

更新日期：2009-04-01 00:00:00

abstract：:Idiopathic fibrosing pancreatitis is an uncommon condition in children and adolescents of unknown aetiology. This syndrome has been reported in 36 cases so far. To our knowledge none of these cases was definitively associated with Crohn's disease. In this report we describe a young female patient who developed Crohn's...

journal_title：European journal of gastroenterology & hepatology

authors： Potamianos S,Koutroubakis IE,Chatzicostas C,Rolles K,Burroughs AK,Kouroumalis EA

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:As treatment of steroid-dependent patients with inflammatory bowel disease (IBD) is controversial, we analysed the efficacy and tolerance of 6-mercaptopurine (6-MP) and methotrexate (MTX) added to prednisone in increasing and maintaining the disease remission rate. METHODS:Seventy-two steroid-dependent IBD ...

journal_title：European journal of gastroenterology & hepatology

authors： Maté-Jiménez J,Hermida C,Cantero-Perona J,Moreno-Otero R

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To examine the influence of dietary factors in Italian patients with ulcerative colitis and Crohn's disease. DESIGN:We studied dietary habits immediately prior to the onset of disease in 104 patients enrolled in a prospective, epidemiological study of the incidence of inflammatory bowel disease in Italy. ME...

journal_title：European journal of gastroenterology & hepatology

authors： Tragnone A,Valpiani D,Miglio F,Elmi G,Bazzocchi G,Pipitone E,Lanfranchi GA

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Intestinal metaplasia is a well-established risk factor in the development of stomach cancer. However, since the specificity is low it would be of great practical value to find a marker to separate cases of intestinal metaplasia into low and high risk for progression to dysplasia/carcinoma. So far this has no...

journal_title：European journal of gastroenterology & hepatology

authors： Gulmann C,Grace A,Leader M,Butler D,Patchett S,Kay E

更新日期：2003-09-01 00:00:00

abstract：:Nitric oxide (NO) can exert both protective and proinflammatory actions in the gastrointestinal tract. NO, formed physiologically by constitutive NO synthases, regulates vascular tone, protects the microvasculature from injury, and modulates adhesion of inflammatory cells. In contrast, expression of an inducible isofo...

journal_title：European journal of gastroenterology & hepatology

authors： Whittle BJ

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVES:Nitric oxide (NO) is involved in the control of pancreatic blood flow and secretion, and its role in the maintenance of pancreatic tissue has been suggested. The aim of our study was to evaluate the influence of NO on pancreatic trophic parameters during acute pancreatitis induction and the pancreas recovery...

journal_title：European journal of gastroenterology & hepatology

authors： Jurkowska G,Rydzewska G,Gabryelewicz A,Dzieciol J

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Serum IgG4 levels are frequently elevated in patients with autoimmune pancreatitis (AIP). AIP is sometimes associated with various extrapancreatic lesions. This study examined whether there is a correlation between serum IgG4 levels and associated extrapancreatic lesions in AIP patients. METHODS:Serum IgG4 l...

journal_title：European journal of gastroenterology & hepatology

authors： Kamisawa T,Imai M,Egawa N,Tsuruta K,Okamoto A

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Spontaneous bacterial peritonitis (SBP) is a common bacterial infection with life-threatening sequelae in cirrhotic ascites. The purpose of this retrospective cohort study was to recognize the predictors of SBP to build up a noninvasive system to exclude or establish an episode of SBP. PATIENT...

journal_title：European journal of gastroenterology & hepatology

authors： Abdel-Razik A,Mousa N,Abdel-Aziz M,Elsherbiny W,Zakaria S,Shabana W,Abed S,Elhelaly R,Elzehery R,Eldars W,El-Bendary M

更新日期：2019-08-01 00:00:00