Audit of a Barrett's epithelium surveillance database.

Abstract:

BACKGROUND:Barrett's epithelium is a premalignant condition in which endoscopic surveillance is recommended but remains contentious. AIM:To audit our Barrett's epithelium surveillance database and to calculate the incidence and natural history of dysplasia and cancer in this cohort. METHODS:A retrospective analysis of a computerised database of patients with columnar lined oesophagus containing specialised intestinal metaplasia was undertaken over a 5-year period. The surveillance protocol was annual endoscopy with 2-cm interval quadrantic biopsies with patients on continuous acid-suppression therapy. RESULTS:A total of 138 (102 men) patients underwent active surveillance. The mean age was 62.1 years and the mean Barrett's epithelium length was 5.9 cm. Ten patients had low-grade dysplasia, with a mean age of 73.5 years, a mean Barrett's epithelium length of 7.8 cm, a prevalence of 7.2% over 5 years and an incidence of 1.4% per annum. Low-grade dysplasia regressed in five patients, persisted in four patients, and was associated with a concurrent squamous carcinoma in one patient. Three patients had high-grade dysplasia at index endoscopy, with no incident cases. One progressed to adenocarcinoma after 2 years. A cancer incidence of one per 202 patient-years of surveillance was found, equivalent to 0.5% per year. CONCLUSION:Short-interval (1-year) endoscopic surveillance of Barrett's epithelium offers little reward. Low-grade dysplasia is uncommon, and no progression to adenocarcinoma was seen in this cohort. No incident high-grade dysplasia was observed. Prospective evaluation of a longer endoscopic surveillance interval in controlled clinical studies is warranted.

authors

Basu KK,Pick B,de Caestecker JS

doi

10.1097/00042737-200402000-00008

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

171-5

issue

2

eissn

0954-691X

issn

1473-5687

pii

00042737-200402000-00008

journal_volume

16

pub_type

杂志文章
  • Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents.

    abstract:OBJECTIVE:To compare the effects of aerobic training (AT) with aerobic plus resistance training (AT+RT) in nonalcoholic fatty liver disease (NAFLD) obese adolescents. DESIGN:Long-term interdisciplinary weight-loss therapy (1 year of clinical, nutritional, psychological, and exercise-related intervention). PARTICIPANT...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MEG.0b013e32835793ac

    authors: de Piano A,de Mello MT,Sanches Pde L,da Silva PL,Campos RM,Carnier J,Corgosinho F,Foschini D,Masquio DL,Tock L,Oyama LM,do Nascimento CM,Tufik S,Dâmaso AR

    更新日期:2012-11-01 00:00:00

  • Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine.

    abstract:OBJECTIVE:To compare the systemic load of 5-aminosalicylic acid (5-ASA) as a basis for potential long-term toxicity during treatment in usual dosage with olsalazine (Dipentum) and one controlled-release mesalazine preparation (Salofalk) in patients with inactive ulcerative colitis. DESIGN:Open, randomized, crossover s...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00042737-199611000-00010

    authors: Karamanolis DG,Papatheodoridis GV,Xourgias V

    更新日期:1996-11-01 00:00:00

  • Trimodal imaging endoscopy reduces the risk of synchronous gastric neoplasia.

    abstract:BACKGROUND AND AIM:The accurate detection of synchronous neoplasia is important to reduce the risk of recurrence after endoscopic resection. Trimodal imaging endoscopy (TMIE) was developed for this purpose. Our aim was to compare the effects of TMIE and white-light imaging endoscopy (WLIE) in gastric neoplasia detectio...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000278

    authors: Gweon TG,Park JM,Lim CH,Kim JS,Cho YK,Kim SW,Choi MG

    更新日期:2015-03-01 00:00:00

  • Ursodeoxycholic acid (UDCA) for the treatment of amoxycillin-clavulanate potassium (Augmentin)-induced intra-hepatic cholestasis: report of two cases.

    abstract::This report describes two patients who developed jaundice within two weeks of receiving an amoxycillin-clavulanate potassium combination. Causes of jaundice, other than drug administration, were excluded. The patients' jaundice and clinical symptoms did not respond to stopping the drug. Ursodeoxycholic acid (750 mg/da...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200012030-00017

    authors: Katsinelos P,Vasiliadis T,Xiarchos P,Patakiouta F,Christodoulou K,Pilpilidis I,Eugenidis N

    更新日期:2000-03-01 00:00:00

  • Leukotriene receptor antagonism in experimental acute pancreatitis in rats.

    abstract:OBJECTIVES:Acute pancreatitis is a multifactorial disease caused by activation of several inflammatory mediators. Leukotrienes, beside other mediators, may be involved in acute pancreatitis. The aim of this study was to investigate the effects of 'zafirlukast', a leukotriene receptor antagonist, in acute pancreatitis a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200404000-00003

    authors: Oruc N,Yukselen V,Ozutemiz AO,Yuce G,Celik HA,Musoglu A,Batur Y

    更新日期:2004-04-01 00:00:00

  • Hyperbaric oxygen as a treatment for malabsorption in a radiation-damaged short bowel.

    abstract::Radiation enteritis can be challenging to diagnose and treat. We report the case of a 44-year-old woman who was diagnosed with a squamous cell carcinoma of the cervix in 1978 and treated with hysterectomy and post-operative radiotherapy. Over the next 20 years she required multiple intestinal operations resulting in s...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200606000-00017

    authors: Huddy JE,Patel P,Johnson MW,Hamilton-Farrell MR,Ede RJ,Sanderson JD

    更新日期:2006-06-01 00:00:00

  • Survival analysis after gastrostomy: a single-centre, observational study comparing radiological and endoscopic insertion.

    abstract:OBJECTIVES:Percutaneous endoscopic gastrostomy (PEG) using the pull through technique is the most widely used insertion method. An alternative is a per-oral image-guided gastrostomy (PIG), which may be advantageous in high-risk patients. As there are no large studies comparing PEG against PIG, we wished to analyse mort...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328332d2dd

    authors: Leeds JS,McAlindon ME,Grant J,Robson HE,Lee FK,Sanders DS

    更新日期:2010-05-01 00:00:00

  • One-week low-dose triple therapy for the eradication of Helicobacter pylori infection.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of two 1-week low-dose triple therapy regimens for the treatment of Helicobacter pylori infection. PATIENTS AND METHODS:Eighty patients with H. pylori infection and peptic ulcer disease (n = 64) or functional dyspepsia (n = 16), with similar demographic and clinical charac...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Labenz J,Stolte M,Rühl GH,Becker T,Tillenburg B,Sollböhmer M,Börsch G

    更新日期:1995-01-01 00:00:00

  • Twenty-four-hour pH measurements in morbid obesity: effects of massive overweight, weight loss and gastric distension.

    abstract:OBJECTIVE:To investigate the influence of untreated (super)morbid obesity and the effects of massive weight loss and chronic gastric distension on gastro-oesophageal reflux. PATIENTS AND METHODS:Seventeen young morbidly obese patients (32 years old; body weight 166.5 kg; body mass index 55 kg/m2) underwent 24-h ambula...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Mathus-Vliegen LM,Tytgat GN

    更新日期:1996-07-01 00:00:00

  • The intestinal lesion of autistic spectrum disorder.

    abstract::This editorial briefly reviews the significance of lymphoid nodular hyperplasia in the intestinal tract of children with autistic spectrum disorder. The distinction between physiological and pathological lymphoid hyperplasia of the intestinal tract is of importance in the context of a possible causative link with auti...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 评论,社论

    doi:10.1097/00042737-200508000-00007

    authors: Jass JR

    更新日期:2005-08-01 00:00:00

  • Stressful life events and recurrent abdominal pain in children in a rural district in Malaysia.

    abstract:OBJECTIVE:The purpose of this study was to look at the correlation between recurrent abdominal pain and the presence of recent stressful life events among schoolchildren in a rural district in Malaysia. METHOD:This is a cross-sectional study of schoolchildren aged 9-15 years based in Kuala Langat, a rural district loc...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200104000-00017

    authors: Boey CC,Goh KL

    更新日期:2001-04-01 00:00:00

  • Acute inflammatory intestinal vascular lesions and in situ abnormalities of the plasminogen activation system in Crohn's disease.

    abstract:OBJECTIVES:The distribution of the intestinal vascular lesions and their relation with the fibrinolysis process are poorly known in Crohn's disease (CD). The mediators of the plasminogen activator system, namely urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and plasminogen activa...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199910000-00007

    authors: Desreumaux P,Huet G,Zerimech F,Gambiez L,Balduyck M,Baron P,Degand P,Cortot A,Colombel JF,Janin A

    更新日期:1999-10-01 00:00:00

  • Characteristics of vacuolating toxin produced by Helicobacter pylori.

    abstract:OBJECTIVE:We sought a good indicator cell line to use in detecting the vacuolating toxin produced by Helicobacter pylori and in examining the characteristics of the toxin. DESIGN AND METHODS:Using five cell lines [baby hamster kidney (BHK-21), human amnion (FL), human uterine cancer (HeLa), rabbit kidney (RK-13) and A...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:

    authors: Kamiya S,Kai M,Ozawa A,Kobayashi H,Shirai T,Harasawa S,Miwa T

    更新日期:1994-12-01 00:00:00

  • Is percutaneous radiofrequency thermal ablation of hepatocellular carcinoma a safe procedure?

    abstract:AIM:To assess the safety and efficacy of percutaneous radiofrequency thermal ablation (RFA) in the treatment of nonsurgical hepatocellular carcinoma (HCC) in daily practice. METHODS:A total of 63 consecutive patients with HCC (solitary nodule

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3282f1cc4a

    authors: Zavaglia C,Corso R,Rampoldi A,Vinci M,Belli LS,Vangeli M,Solcia M,Castoldi C,Prisco C,Vanzulli A,Pinzello G

    更新日期:2008-03-01 00:00:00

  • Quality of Barrett's surveillance in The Netherlands: a standardized review of endoscopy and pathology reports.

    abstract:OBJECTIVE:The quality of Barrett's surveillance relies on an adequate endoscopic inspection, obtaining a sufficient number of biopsy specimens, good communication of the endoscopic findings to the pathologist, and an accurate description of the histological findings by the pathologist. The aim of this study was to asse...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e3282f8295d

    authors: Curvers WL,Peters FP,Elzer B,Schaap AJ,Baak LC,van Oijen A,Mallant-Hent RM,Ten Kate F,Krishnadath KK,Bergman JJ

    更新日期:2008-07-01 00:00:00

  • Abdominal pain in adults with cystic fibrosis.

    abstract::Abdominal pain is a common symptom in individuals with cystic fibrosis (CF). As prognosis has improved, CF has changed from a pediatric disease to the current situation wherein most people with CF are adults. With improved survival, the spectrum of pathologies causing abdominal pain in CF has shifted. Despite this, th...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/MEG.0000000000000011

    authors: Nash EF,Ohri CM,Stephenson AL,Durie PR

    更新日期:2014-02-01 00:00:00

  • Risk factors for symptomatic stone recurrence after transpapillary laser lithotripsy for difficult bile duct stones using a laser with a stone recognition system.

    abstract:BACKGROUND:Laser-induced shock-wave lithotripsy (LISL) is successfully used for the treatment of difficult bile duct stones. The aim of this study was to assess the long-term risk for a symptomatic bile duct stone recurrence after LISL and to detect risk factors predicting recurrence. METHODS:Between 1993 and 2001, 80...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200605000-00003

    authors: Jakobs R,Hartmann D,Kudis V,Eickhoff A,Schilling D,Weickert U,Siegler KE,Riemann JF

    更新日期:2006-05-01 00:00:00

  • Retrograde detection of the intrahepatic portal vein in primary biliary cirrhosis: is sinusoidal blockage the underlying pathophysiology?

    abstract:OBJECTIVE:The aim of this study was to explore the underlying pathophysiological mechanism for portal hypertension in primary biliary cirrhosis (PBC) using radiological findings. PATIENTS AND METHODS:The study included 10 patients with PBC (Scheuer stage I, one patient; stage II, two patients; and cirrhosis, seven pat...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000268

    authors: Maruyama H,Kondo T,Sekimoto T,Takahashi M,Fujiwara K,Imazeki F,Yokosuka O

    更新日期:2015-03-01 00:00:00

  • Liver steatosis in patients with chronic hepatitis B infection: host and viral risk factors.

    abstract:BACKGROUND:Liver steatosis (LS) and chronic infection with hepatitis B virus (HBV) are two common causes of chronic liver disease in Iran. LS is also a common histopathological feature of chronic hepatitis B (CHB). Association of chronic HBV infection and LS has not been extensively studied. AIM:We investigated the pr...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328326792e

    authors: Minakari M,Molaei M,Shalmani HM,Mohammad Alizadeh AH,Jazi AH,Naderi N,Shavakhi A,Mashayekhi R,Zali MR

    更新日期:2009-05-01 00:00:00

  • Recurrent cardiac tamponade as first manifestation of gastric cancer.

    abstract::Malignant pericardial effusion is an uncommon disorder and is usually caused by far advanced lung cancer, breast cancer, lymphoma and leukaemia. Pericardial effusion in recurrent gastric cancer has been reported in only three patients. We report the case of a 53-year-old male with sudden onset of dyspnoea, pericardial...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199807000-00018

    authors: Fazeny B,Meghdadi S,Dejaco C,Kastner J,Marosi C,Schmidinger H

    更新日期:1998-07-01 00:00:00

  • Hepatic stellate cell activation and hepatic fibrosis in children with type 1 autoimmune hepatitis: an immunohistochemical study of paired liver biopsies before treatment and after clinical remission.

    abstract:OBJECTIVES:The activation of hepatic stellate cells (HSC) is considered the most important event in hepatic fibrogenesis. The precise mechanism of this process is unknown in autoimmune hepatitis (AIH), and more evidence is needed on the evolution of fibrosis. The aim of this study was to assess these aspects in childre...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328326cab6

    authors: Maia JM,Maranhão Hde S,Sena LV,Rocha LR,Medeiros IA,Ramos AM

    更新日期:2010-03-01 00:00:00

  • Omeprazole, but not pantoprazole, reduces the antiplatelet effect of clopidogrel: a randomized clinical crossover trial in patients after myocardial infarction evaluating the clopidogrel-PPIs drug interaction.

    abstract:BACKGROUND:Proton pump inhibitors (PPIs) are usually prescribed to patients undergoing dual antiplatelet therapy to decrease the risk of gastrointestinal bleeding. Recent studies have raised concerns that PPIs could reduce clopidogrel's efficacy by competitive inhibition of cytochrome P450 2C19 isoenzyme. All PPIs are ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MEG.0b013e3283460110

    authors: Fontes-Carvalho R,Albuquerque A,Araújo C,Pimentel-Nunes P,Ribeiro VG

    更新日期:2011-05-01 00:00:00

  • Antigen specificity of circulating anti-neutrophil cytoplasmic antibodies in inflammatory bowel disease.

    abstract:OBJECTIVES:To characterize the antigen specificity of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) in inflammatory bowel disease (IBD). DESIGN:Analysis of the prevalence of circulating ANCAs in patients with ulcerative colitis and Crohn's disease, by both non-specific methods (immunofluorescence against ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:

    authors: Kossa K,Coulthart A,Ives CT,Pusey CD,Hodgson HJ

    更新日期:1995-08-01 00:00:00

  • A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care.

    abstract:BACKGROUND:Reports suggest that gluten sensitivity (GS) exists in the absence of coeliac disease (CD). This clinical entity has been termed noncoeliac gluten sensitivity (NCGS). OBJECTIVES:To determine the population prevalence of self-reported GS and referral characteristics to secondary care. PATIENTS AND METHODS:A...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/01.meg.0000435546.87251.f7

    authors: Aziz I,Lewis NR,Hadjivassiliou M,Winfield SN,Rugg N,Kelsall A,Newrick L,Sanders DS

    更新日期:2014-01-01 00:00:00

  • Hodgkin's disease presenting as cholestatic hepatitis with prominent ductal injury.

    abstract::In advanced stages of Hodgkin's disease, liver involvement is common. However, Hodgkin's disease mimicking cholestatic hepatitis at presentation is rare. We describe a patient with Hodgkin's disease who was initially considered to have acute cholestatic hepatitis. Liver biopsy demonstrated prominent bile duct injury a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200203000-00019

    authors: Liangpunsakul S,Kwo P,Koukoulis GK

    更新日期:2002-03-01 00:00:00

  • Proton pump inhibitors reduce phlebotomy burden in patients with HFE-related hemochromatosis: a systematic review and meta-analysis.

    abstract:BACKGROUND AND AIMS:Proton pump inhibitors (PPIs) may reduce iron absorption and serum ferritin levels in patients with homeostatic iron regulator (HFE)-related hemochromatosis, reducing the need for frequent phlebotomies. Our study aimed to perform for the first time a meta-analysis of existing observational and rando...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001857

    authors: Dirweesh A,Anugwom CM,Li Y,Vaughn BP,Lake J

    更新日期:2020-08-04 00:00:00

  • The extent of duodenogastric reflux in gastro-oesophageal reflux disease.

    abstract:BACKGROUND:It is known that duodenogastro-oesophageal reflux (DGOR) increases with worsening gastro-oesophageal reflux disease (GORD). It is unclear whether this is accompanied by increasing duodenogastric reflux (DGR). OBJECTIVE:To investigate the extent of DGR in a control group and 66 patients with GORD, using the ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200101000-00002

    authors: Marshall RE,Anggiansah A,Owen WA,Manifold DK,Owen WJ

    更新日期:2001-01-01 00:00:00

  • Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remission.

    abstract:BACKGROUND:Eosinophilic oesophagitis (EO) is a chronic inflammatory disorder of the oesophagus that is rapidly increasing in prevalence. Although systemic and topical corticosteroids are effective in treating EO, some patients develop corticosteroid dependency. Alternative therapeutic approaches that avoid corticostero...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32825a6ab4

    authors: Netzer P,Gschossmann JM,Straumann A,Sendensky A,Weimann R,Schoepfer AM

    更新日期:2007-10-01 00:00:00

  • Relationship between pre-sarcopenia and quality of life in patients with chronic liver disease: a cross-sectional study.

    abstract:AIM:This study aimed to clarify the relationship between pre-sarcopenia (PS) and quality of life (QOL) in patients with chronic liver disease (CLD). PATIENTS AND METHODS:This cross-sectional study evaluated 335 patients with CLD. PS was diagnosed on the basis of the assessment criteria by the Japan Society of Hepatolo...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001415

    authors: Ohashi K,Ishikawa T,Imai M,Suzuki M,Hoshii A,Abe H,Koyama F,Nakano T,Ueki A,Noguchi H,Hasegawa E,Hirosawa S,Kobayashi M,Hirosawa H,Sato K,Munakata M,Yoshida T

    更新日期:2019-11-01 00:00:00

  • Prevalence and clinical features of heterotopic gastric mucosa in the upper oesophagus (inlet patch).

    abstract:AIM:To determine the prevalence of heterotopic gastric mucosa in the upper oesophagus (inlet patch) and the factors that may influence its finding. To study its macroscopic and microscopic characteristics and its relationship with symptoms and oesophago-gastroduodenal diseases. PATIENTS AND METHODS:The study was carri...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200012070-00005

    authors: Maconi G,Pace F,Vago L,Carsana L,Bargiggia S,Bianchi Porro G

    更新日期:2000-07-01 00:00:00