The effect of incisura angularis biopsy sampling on the assessment of gastritis stage.

Abstract:

OBJECTIVES:It is important to stratify patients according to the magnitude of risk for gastric cancer development; the OLGA (Operative Link for Gastritis Assessment) and OLGIM (Operative Link on Gastric Intestinal Metaplasia) staging systems of lesions in the stomach mucosa have been proposed for this purpose. There are some discrepancies in the current guidelines regarding the value of incisura angularis biopsies. The aim of our study was to assess the value of incisura angularis biopsy in staging gastritis according to the OLGA and OLGIM systems by examining the atrophic, metaplastic and inflammatory changes in the antrum, incisura angularis and corpus. PATIENTS AND METHODS:We enrolled 835 patients undergoing upper endoscopy. Three expert gastrointestinal pathologists graded biopsy specimens according to the Sydney classification and the stage of gastritis was assessed by the OLGA and OLGIM systems. RESULTS:The results demonstrated that severe atrophic, metaplastic and chronic inflammatory changes were more frequently observed in the incisura angularis mucosa than in the antrum or corpus mucosae (P<0.05). There was a general downgrading of stage by 18.0% for OLGA and by 4.0% for OLGIM when the incisura angularis was excluded from the staging. Furthermore, there was a 30-35% downgrading for high-risk OLGA/OLGIM stages. CONCLUSION:The incisura angularis undergoes more severe atrophic, metaplastic and chronic inflammatory changes than the antrum and corpus. Incisura angularis biopsies should be routinely included in the biopsy sampling protocol.

authors

Isajevs S,Liepniece-Karele I,Janciauskas D,Moisejevs G,Funka K,Kikuste I,Vanags A,Tolmanis I,Leja M

doi

10.1097/MEG.0000000000000082

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

510-3

issue

5

eissn

0954-691X

issn

1473-5687

journal_volume

26

pub_type

杂志文章
  • Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis.

    abstract:OBJECTIVES:The hybrid allele of the carboxyl ester lipase gene (CEL-HYB1) is a genetic risk factor for chronic pancreatitis (CP) although the mechanism promoting disease development is largely unknown. Here, we aimed to clinically describe subjects carrying the CEL-HYB1 allele and to elucidate why the protein product i...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001963

    authors: Tjora E,Gravdal A,Engjom T,Cnop M,Johansson BB,Dimcevski GG,Molven A,Fjeld K

    更新日期:2020-10-16 00:00:00

  • Guidelines for the management of dyspepsia.

    abstract::Dyspepsia is a common problem necessitating strategies for investigation and management because of the scarcity of available resources for investigation, i.e. endoscopy, and the need to focus on those at risk of serious disease. It is agreed that those in the older age group, with the presence of alarm symptoms or non...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 评论,杂志文章

    doi:10.1097/00042737-199903000-00001

    authors: Mullins PD,Colin-Jones DG

    更新日期:1999-03-01 00:00:00

  • Hepatitis C virus treatment rates and outcomes in HIV/hepatitis C virus co-infected individuals at an urban HIV clinic.

    abstract:OBJECTIVES:The factors associated with hepatitis C virus (HCV) treatment uptake and responses were assessed among HCV/HIV co-infected individuals referred for HCV therapy at an urban HIV clinic. METHODS:Retrospective review of HIV/HCV patients enrolled in the HCV treatment program at the John Ruedy Immunodeficiency Cl...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328341ef54

    authors: Murray MC,Barrios R,Zhang W,Hull M,Montessori V,Hogg RS,Montaner JS

    更新日期:2011-01-01 00:00:00

  • Mechanisms of liver cell damage and repair.

    abstract::Acute liver failure arises from an imbalance between liver cell death and regeneration. The severity of the insult determines whether liver cells die by apoptosis or necrosis, and this in turn affects the magnitude of the inflammatory reaction. Liver cell death occurs through complex cellular interactions and is media...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-199909000-00002

    authors: Thomson RK,Arthur MJ

    更新日期:1999-09-01 00:00:00

  • Prognosis of patients with gastric variceal bleeding after endoscopic variceal obturation according to the type of varices.

    abstract:BACKGROUND AND AIMS:This study was performed to evaluate the treatment efficacy of endoscopic variceal obturation (EVO) in patients with gastric variceal bleeding (GVB) according to the type of varices. PATIENTS AND METHODS:All patients who were treated with EVO for bleeding from gastric varices (GVs) were included. P...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001271

    authors: Lee HA,Chang JM,Goh HG,Kim TH,Lee YS,Suh SJ,Jung YK,Choi HS,Kim ES,Kim JH,An H,Seo YS,Yim HJ,Jeen YT,Yeon JE,Chun HJ,Byun KS,Um SH,Kim CD,Korean Portal Hypertension Study Group.

    更新日期:2019-02-01 00:00:00

  • Haemodynamic changes after high-volume plasmapheresis in patients with chronic and acute liver failure.

    abstract:OBJECTIVE:To evaluate the haemodynamic changes during treatment with high-volume plasmapheresis in patients with chronic liver failure compared to patients with acute liver failure. METHODS:Haemodynamic measurements were performed with a Swan-Ganz catheter and thermodilution technique. High-volume plasmapheresis (mean...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199701000-00014

    authors: Clemmesen JO,Larsen FS,Ejlersen E,Schiødt FV,Ott P,Hansen BA

    更新日期:1997-01-01 00:00:00

  • Sclerosing peritonitis complicated by sepsis: a potential cause of portal hypertension.

    abstract::A 27-year-old woman with chronic renal failure, who had been treated with chronic ambulatory peritoneal dialysis and had developed sclerosing peritonitis, was admitted to the hospital with intra-abdominal sepsis. In spite of antibiotic therapy, sepsis recurred and was associated with intrahepatic cholestasis. In addit...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199801000-00017

    authors: Jones EA,Bronkhorst CM,de Jonge E,ten Kate FJ

    更新日期:1998-01-01 00:00:00

  • A systematic review and meta-analysis on outcomes after Rx or R1 endoscopic resection of superficial gastric cancer.

    abstract:OBJECTIVE:Endoscopic resection is a standard treatment for gastric superficial lesions. A positive or a nonevaluable margin is considered a noncurative criterion. We aimed to systematically review recurrence, residual disease, lymph node metastasis (LNM) and cancer-related death following Rx/R1 resection of gastric les...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MEG.0000000000000440

    authors: Figueiredo PC,Pimentel-Nunes P,Libânio D,Dinis-Ribeiro M

    更新日期:2015-11-01 00:00:00

  • Clinical and microbiological characteristics associated with mortality in spontaneous bacterial peritonitis: a multicenter cohort study.

    abstract:OBJECTIVES:Spontaneous bacterial peritonitis (SBP) is a prevalent and high mortality complication of cirrhosis. We aimed to describe these patients' clinical and microbiological characteristics and evaluate their impact on outcomes. METHODS:This was a retrospective cohort study including 139 consecutive patients with ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000700

    authors: Oliveira AM,Branco JC,Barosa R,Rodrigues JA,Ramos L,Martins A,Karvellas CJ,Cardoso FS

    更新日期:2016-10-01 00:00:00

  • Heterotopic gastric mucosa of the proximal oesophagus (inlet patch): endoscopic prevalence, histological and clinical characteristics in paediatric patients.

    abstract:BACKGROUND:Heterotopic gastric mucosa is found in the proximal oesophagus, just below the upper oesophageal sphincter, and is encountered when the oesophagus is examined carefully during endoscopy. AIMS:In this study on paediatric patients, we aimed to determine the endoscopic prevalence of heterotopic gastric mucosa ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000177

    authors: Rodríguez-Martínez A,Salazar-Quero JC,Tutau-Gómez C,Espín-Jaime B,Rubio-Murillo M,Pizarro-Martín A

    更新日期:2014-10-01 00:00:00

  • Quality of life in patients with functional dyspepsia: a prospective 1-year follow-up study in Spanish patients.

    abstract:BACKGROUND AND AIMS:The natural history of functional dyspepsia is not well known. We prospectively assess the quality of life and severity of symptoms in a group of Spanish patients with functional dyspepsia. PATIENTS AND METHODS:One hundred and twelve consecutive patients with functional dyspepsia, according to Rome...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200311000-00005

    authors: Gutiérrez A,Rodrigo L,Riestra S,Fernández E,Cadahia V,Tojo R,Fuentes D,Niño P,Olcoz JL

    更新日期:2003-11-01 00:00:00

  • Efficacy of albumin-bilirubin score to predict hepatic encephalopathy in patients underwent transjugular intrahepatic portosystemic shunt.

    abstract:BACKGROUND AND AIMS:The occurrence of hepatic encephalopathy is one of the main factors limiting the development and application of transjugular intrahepatic portosystemic shunt (TIPS). Our study aimed to verify the efficacy of the albumin-bilirubin score, an objective and simple scoring system, to predict post-TIPS he...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001801

    authors: Lin X,Gao F,Wu X,Cai W,Chen X,Huang Z

    更新日期:2020-06-11 00:00:00

  • Spontaneous bacterial peritonitis caused by quinolone-resistant Escherichia coli: could steroid therapy play a role?

    abstract::Prophylaxis with norfloxacin has been shown to be effective in preventing spontaneous bacterial peritonitis (SBP) in liver cirrhosis. This therapy is associated with the appearance of quinolone-resistant Escherichia coli. However, only four cases of SBP caused by quinolone-resistant E. coli have been reported so far. ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200201000-00014

    authors: Cereto F,Genescà J,Smithson A,González A,Moreno G,del Valle Ortiz O,Esteban R,Guardia J

    更新日期:2002-01-01 00:00:00

  • Higher quality of life after metal stent placement compared with plastic stent placement for malignant extrahepatic bile duct obstruction: a randomized controlled trial.

    abstract:OBJECTIVE:For palliation of extrahepatic bile duct obstruction, self-expandable metal stents (SEMS) are superior to plastic stents in terms of stent patency and occurrence of stent dysfunction. We assessed health-related quality of life (HRQoL) after stent placement to investigate whether this also results in a differe...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/MEG.0000000000000762

    authors: Walter D,van Boeckel PG,Groenen MJ,Weusten BL,Witteman BJ,Tan G,Brink MA,Nicolai J,Tan AC,Alderliesten J,Venneman NG,Laleman W,Jansen JM,Bodelier A,Wolters FL,van der Waaij LA,Breumelhof R,Peters FT,Scheffer RC,Stey

    更新日期:2017-02-01 00:00:00

  • In-vivo effect of nicotine on cytokine production by human non-adherent mononuclear cells.

    abstract:OBJECTIVE:Ulcerative colitis (UC) is predominantly a disease of non-smokers and treatment with transdermal nicotine improves symptoms in UC patients, whereas smoking seems to have a deleterious effect in patients with Crohn's disease (CD). In CD the cytokine profile is of a dominant TH1 (T helper 1) pattern whereas in ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199610000-00016

    authors: Madretsma S,Wolters LM,van Dijk JP,Tak CJ,Feyerabend C,Wilson JH,Zijlstra FJ

    更新日期:1996-10-01 00:00:00

  • Open-access versus hospital-initiated flexible sigmoidoscopy: a comparative audit of efficacy.

    abstract:BACKGROUND AND AIMS:There is a continuing demand for the provision of open-access endoscopy services. While open-access gastroscopy is now a well-established practice in most hospitals, open-access flexible sigmoidoscopy (OAS) is not yet available to the same extent. We present our early experience with OAS, a new serv...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200106000-00007

    authors: Verma S,Giaffer MH

    更新日期:2001-06-01 00:00:00

  • Prognostic significance of inflammation-based score in patients with hepatocellular carcinoma after liver transplantation.

    abstract:BACKGROUND:Recent studies have revealed that combining of the platelet to lymphocyte ratio (PLR) and the neutrophil to lymphocyte ratio (NLR) [(combination of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio (CNP)] links with dismal prognosis in diverse cancers. Here, we elucidated the prognostic significance ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000002037

    authors: Kong W,Qu E,Sheng N,Zhang J,Li X,Zheng J,Gao Y

    更新日期:2021-01-06 00:00:00

  • Decreased parasympathetic activity in patients with functional dyspepsia.

    abstract:OBJECTIVE:Functional dyspepsia (FD) can be described as the presence of symptoms such as bothersome postprandial fullness, early satiation, epigastric pain, and burning without any evidence of structural disease. The aim of this study was to evaluate the autonomic nervous system using heart rate variability (HRV) in pa...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000111

    authors: Dal K,Deveci OS,Kucukazman M,Ata N,Sen O,Ozkan S,Yeniova AO,Başer S,Beyan E,Nazligul Y,Yavuz B,Ertugrul DT

    更新日期:2014-07-01 00:00:00

  • Selection criteria for pre-operative endoscopic retrograde cholangiography and endoscopic-laparoscopic treatment of biliary stones.

    abstract:OBJECTIVE:Pre-operative endoscopic retrograde cholangiography (ERCP) prior to laparoscopic cholecystectomy (LC) is the most common treatment of gallbladder and common bile duct (CBD) stones. In this study we evaluate our selection criteria for pre-operative ERCP and the results of endoscopic-laparoscopic treatment in p...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199907000-00017

    authors: Masci E,Fanti L,Mariani A,Guerini S,Zuliani W,Baccari P,Giacomelli M,Tittobello A

    更新日期:1999-07-01 00:00:00

  • Stenting of malignant upper oesophageal obstruction: experience in a regional hospital in Singapore.

    abstract::Oesophageal stenting for palliation of malignant obstruction with self-expanding metallic stents is undoubtedly well established. Numerous studies have proven it to be safe and easy to perform with good clinical outcomes. However, stenting of the upper oesophagus is still regarded with apprehension, with many endoscop...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283496543

    authors: Yim HB

    更新日期:2011-10-01 00:00:00

  • Immunoglobulin coating of faecal bacteria in inflammatory bowel disease.

    abstract:OBJECTIVE:An inappropriate mucosal immune response to the commensal bacterial flora may play a role in the pathogenesis of inflammatory bowel disease (IBD). In this study we determined the percentage of immunoglobulin-coated bacteria in the stools of patients and controls. METHODS:Faecal samples were obtained from 18 ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/01.meg.0000108346.41221.19

    authors: van der Waaij LA,Kroese FG,Visser A,Nelis GF,Westerveld BD,Jansen PL,Hunter JO

    更新日期:2004-07-01 00:00:00

  • Length of endoscopic workup in gastrointestinal bleeding.

    abstract:BACKGROUND:The number of procedures utilized in the general management of gastrointestinal bleeding (GIB) has not been investigated previously. We used the National Endoscopic Database of the Clinical Outcomes Research Initiative for an observational study to analyze the average length of workup in GIB. METHODS:The el...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000693

    authors: Woodward Z,Williams JL,Sonnenberg A

    更新日期:2016-10-01 00:00:00

  • Hepatitis C and hepatitis C-related advanced liver disease hospitalisation trends before and after the Strategic Plan for Tackling Hepatitis C in the National Health System.

    abstract:INTRODUCTION:This work evaluates the burden and trends of hepatitis C virus (HCV)-associated hospitalisations in Spain before and after the implementation of the Strategic Plan for Tackling Hepatitis C in the National Health System in 2015. METHODS:HCV-related hospitalisation discharges from 2005 to 2017 were obtained...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001841

    authors: Garrido-Estepa M,Latasa P,Flores-Herrera J,García Comas L

    更新日期:2020-07-29 00:00:00

  • Report of a collaborative trial to investigate the performance of the R5 enzyme linked immunoassay to determine gliadin in gluten-free food.

    abstract:OBJECTIVE:Analytical methods for measurements of gluten in the low level range of 20-200 ppm of gluten, as required for gluten-free food, have never been endorsed by the Codex Alimentarius. With the aim of investigating standardized and reliable methods for the detection of gliadin in food with detection limits lower t...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00042737-200510000-00008

    authors: Méndez E,Vela C,Immer U,Janssen FW

    更新日期:2005-10-01 00:00:00

  • A new organotypic model to study cell interactions in the intestinal mucosa.

    abstract:BACKGROUND:Recently, we demonstrated that freshly elutriated monocytes differentiate into macrophages with a phenotype similar to that of intestinal macrophages in a three-dimensional model of intestinal epithelial cells. Here we describe a more organotypic model to study cell interactions in the intestinal mucosa. ME...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200608000-00017

    authors: Spottl T,Hausmann M,Gunckel M,Herfarth H,Herlyn M,Schoelmerich J,Rogler G

    更新日期:2006-08-01 00:00:00

  • Influence of biliary anastomosis on recovery from secondary biliary cirrhosis.

    abstract:OBJECTIVE:The influence of choledochoduodenostomy and choledochojejunostomy on the repair of hepatic lesions secondary to biliary obstruction is not well known. The aim of the present study was to compare the effects of choledochoduodenostomy and choledochojejunostomy on the recovery of these lesions in rats with bilia...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3283551fed

    authors: dos Santos JS,Kemp R,de Andrade MF,Neder L

    更新日期:2012-09-01 00:00:00

  • Evaluation of serum procollagen C-proteinase enhancer 1 level as a fibrosis marker in patients with chronic hepatitis B.

    abstract:AIM:Although liver biopsy has long been considered the gold standard for staging fibrosis, because of the disadvantages and risks of biopsy, several noninvasive processes such as serum biomarkers have been introduced for the assessment of liver fibrosis. The aim of this study was to assess the diagnostic value of serum...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001123

    authors: Gokce O,Ozenirler S,Atak Yucel A,Oruklu N,Yilmaz Esendagli G,Karahan S

    更新日期:2018-08-01 00:00:00

  • Life threatening diarrhoea ultimately cured by surgery.

    abstract::A 30-year-old previously healthy woman was diagnosed as having a vasoactive intestinal polypeptide (VIP)-producing tumour of the pancreas. Her medical history was typical for neuroendocrine gastrointestinal tumours, presenting initially with non-specific symptoms but eventually she developed life-threatening manifesta...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199811000-00011

    authors: Sjöqvist U,Permert J,Löfberg R,Larsson J,Gadaleanu V,Adrian TE

    更新日期:1998-11-01 00:00:00

  • The use of antiendotoxin peptides in obstructive jaundice endotoxemia.

    abstract:BACKGROUND:Two novel antiendotoxin peptides, P6 and C1, may reduce the inflammatory response. This study aimed to determine the effect of endotoxin on hepatic cytokine response and to assess P6 and C1-related attenuation of the proinflammatory response to endotoxemia, in experimental biliary obstruction. MATERIALS AND...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32834dfb8c

    authors: Jones C,Badger SA,Black JM,McFerran NV,Hoper M,Diamond T,Parks RW,Taylor MA

    更新日期:2012-03-01 00:00:00

  • Colonic endocrine cells in patients with carcinoma of the colon.

    abstract:OBJECTIVE:To investigate the colonic endocrine cells in patients with colon carcinoma in order to establish a possible abnormality. PATIENTS:Twelve patients with colon adenocarcinoma (eight women and four men; mean age 69 years; range 52-88 years) were studied. As controls, macroscopically and histologically normal ti...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199806000-00015

    authors: El-Salhy M,Mahdavi J,Norrgård O

    更新日期:1998-06-01 00:00:00