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Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome.

Abstract：

OBJECTIVE:Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared with nonprocessed cereals. METHODS:This investigation is a randomized double-blind, cross-over multicentre prospective study of 26 intestinal resected out patients, considered as short bowel syndrome patients. The patients were divided into groups A or B, in accordance with the first allocated treatment. Subgroup analyses of the underlying diagnoses and type of surgical procedure were performed. The studied parameters were faecal volume, nocturnal stools, abdominal pain/discomfort, health-related quality of life, peripheral blood tests and anthropometric data. RESULTS:In both groups, intake of nonprocessed cereals significantly decreased the faecal volume. The subgroup analyses of patients with a history of ulcerative colitis (compared with Crohn's disease) and nonileostomy-operated procedure (compared with ileostomi-operated procedure) showed significantly decreased faecal volume during nonprocessed cereals intake. Peripheral blood tests, quality of life and anthropometry were not affected. CONCLUSION:In this study, nonprocessed cereals seemed to be as effective as specially processed cereals in decreasing faecal volume in general and especially in ulcerative colitis patients (mainly operated with nonileostomy techniques). Our results indicate that use of supplementary cereals is safe for this group of patients, but should optimally include evaluation of the underlying diagnosis and the surgical method used.

journal_name

Eur J Gastroenterol Hepatol

journal_title

European journal of gastroenterology & hepatology

authors

Pagoldh M,Eriksson A,Heimtun E,Kvifors E,Sternby B,Blomquist L,Lapidus A,Suhr O,Lange S,Karlbom U,Nordström D,Rettrup B

doi

10.1097/MEG.0b013e328303c00a

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

1085-93

issue

eissn

0954-691X

issn

1473-5687

pii

00042737-200811000-00006

journal_volume

pub_type

杂志文章,多中心研究,随机对照试验

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Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome.