Abstract:
:The developmental patterns of thyroid-stimulating hormone (TSH) was examined in female Long-Evans rats by radioimmunoassay of pituitary and plasma from 5 through 80 days of age. The effects of hypothyroidism on normal TSH levels were examined in animals radiothyroidectomized at birth. Control animals showed a peak in circulating TSH levels at day 12 followed by lower levels through day 30, and even lower levels at day 80 when values were those of adult animals. Hypothyroid females had higher plasma TSH levels than controls from days 10 through 30 with no distinct peak at day 12. Pituitary content reached a peak at day 18 and was always higher in control than hypothyroid animals.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Cons JM,Umezu M,Timiras PSdoi
10.1210/endo-97-1-237subject
Has Abstractpub_date
1975-07-01 00:00:00pages
237-40issue
1eissn
0013-7227issn
1945-7170journal_volume
97pub_type
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