Abstract：
:Parkinson's disease (PD) and Alzheimer's dementia (AD) are often associated with an autonomic neuropathy. The extent of autonomic involvement, however is poorly defined and unpredictable. In order to assess the autonomic cardiovascular regulation baroreflex sensitivity (BRS) was determined non-invasively in 23 patients (age: 65 +/- 9.3 years) with PD and 24 patients with AD (age: 72.3 +/- 7.2 years). The results were compared with those on 22 healthy age- and sex-matched volunteers. Patients with PD and AD exhibited marked abnormalities in cardiovascular autonomic reflex regulation showed by markedly depressed BRS. The possible predictive value of centrally based depression of baroreflex sensitivity necessitates further studies.
journal_name
Neurobiol Agingjournal_title
Neurobiology of agingauthors
Szili-Török T,Kálmán J,Paprika D,Dibó G,Rózsa Z,Rudas Ldoi
10.1016/s0197-4580(01)00210-xsubject
Has Abstractpub_date
2001-05-01 00:00:00pages
435-8issue
3eissn
0197-4580issn
1558-1497pii
S019745800100210Xjournal_volume
22pub_type
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