Combined therapy with interferon and ribavirin in chronic hepatitis C does not affect serum quasispecies diversity.

abstract：:An 18-year-old male who developed a pancreatic pseudocyst during the active phase of polyarteritis nodosa is described. Cytotoxic therapy with cyclophosphamide and prednisolone was unable to control the manifestation of this disease, and he required percutaneous drainage of the pseudocyst. The drainage resulted in com...

journal_title：Digestive diseases and sciences

authors： Ghosh AK,Sakhuja V,Malik N,Kathuria P,Chugh KS

更新日期：1993-07-01 00:00:00

abstract：:Verapamil, a type-1 calcium-channel blocker, given intraperitoneally, macroscopically protected the gastric mucosa of rats from 96% ethanol-induced lesions in a dose-dependent fashion. This effect was significant when verapamil at 10 or 20 mg/kg was given 1 hr before ethanol. Histopathologically, verapamil prevented t...

journal_title：Digestive diseases and sciences

authors： Gutiérrez-Cabano CA

更新日期：1993-11-01 00:00:00

abstract：:Previous studies have suggested that the cyclic entry of bile into the duodenum during fasting regulates interdigestive patterns of motility by releasing the putative regulatory hormone motilin. Our aim was to determine if cyclic secretion of bile into the duodenum regulates interdigestive myoelectric activity and pla...

journal_title：Digestive diseases and sciences

authors： Hughes SJ,Behrns KE,Sarr MG

更新日期：1993-06-01 00:00:00

abstract：:A 68-year-old woman developed exfoliative dermatitis while taking cimetidine for gastritis. She had no history of previous drug reactions, allergies, or skin disorders and had taken no other medications for three months. Although cimetidine is a relatively safe drug, severe reactions such as exfoliative dermatitis can...

journal_title：Digestive diseases and sciences

authors： Yantis PL,Bridges ME,Pittman FE

更新日期：1980-01-01 00:00:00

abstract：:Fibronectin (FN) is important for wound healing via cell proliferation, adhesion, differentiation, and matrix formation. Fetal types of FN mRNA, which include the region of EIIIA or EIIIB, are well expressed during embryonic development and wound healing. This study was done to investigate the mRNA expression of full-...

journal_title：Digestive diseases and sciences

authors： Tominaga K,Higuchi K,Watanabe T,Fujiwara Y,Kim S,Arakawa T,Iwao H,Kuroki T

更新日期：2001-02-01 00:00:00

abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...

journal_title：Digestive diseases and sciences

authors： Shimouchi A,Nose K,Takaoka M,Hayashi H,Kondo T

更新日期：2009-08-01 00:00:00

abstract：:On-demand therapy is effective for maintaining symptoms control in nonerosive gastroesophageal reflux disease (GERD). Our aim was to assess the clinical effectiveness of on-demand therapy with a proton pump inhibitor (PPI) in mild GERD (nonerosive and low-grade esophagitis), its impact on health-related quality of lif...

journal_title：Digestive diseases and sciences

authors： Ponce J,Argüello L,Bastida G,Ponce M,Ortiz V,Garrigues V

更新日期：2004-06-01 00:00:00

abstract：:In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...

journal_title：Digestive diseases and sciences

authors： Phillips WT,Schwartz JG,McMahan CA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...

journal_title：Digestive diseases and sciences

authors： Tsai HI,Tsai YF,Liou SC,Su MY,Lin CC,Chang CJ,Yu HP

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma is a devastating disease with a 2% 5-year survival if the disease has spread outside the liver. The enzyme aspartate beta-hydroxylase (ASPH) has been demonstrated to be highly expressed in cholangiocarcinoma but not in normal bile ducts and found to stimulate tumor cell migration. In addit...

journal_title：Digestive diseases and sciences

authors： Nagaoka K,Ogawa K,Ji C,Cao KY,Bai X,Mulla J,Cheng Z,Wands JR,Huang CK

更新日期：2020-05-22 00:00:00

abstract：:The effects of vasoactive intestinal polypeptide (VIP), glucagon, and secretin on lower esophageal sphincter pressure were investigated in awake baboons. The three hormones were compared with respect to effect on (1) resting lower esophageal sphincter pressure and (2) maximal stimulatory response to pentagastrin. VIP ...

journal_title：Digestive diseases and sciences

authors： Siegel SR,Brown FC,Castell DO,Johnson LF,Said SI

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important factor in malignant tumors, and glycolysis is a major metabolic contributor in their development. Glycolytic enzymes have gained increasing attention as potential therapeutic targets because they are associated with cancer-specific metabolism. Fructose-bisphosphate aldolase A (ALDOA),...

journal_title：Digestive diseases and sciences

authors： Li X,Jiang F,Ge Z,Chen B,Yu J,Xin M,Wang J,An L,Wei J,Wu L

更新日期：2019-11-01 00:00:00

abstract：:Phlebosclerosis of the mesenteric vein is a rare condition causing chronic intestinal ischemia, it has only been reported in Japan. A 56-year-old man with liver cirrhosis and hepatic tumor presented with phlebosclerosis of mesenteric vein without any abdominal symptoms. He was admitted for examination of suspected hep...

journal_title：Digestive diseases and sciences

authors： Oshitani N,Matsumura Y,Kono M,Tamori A,Higuchi K,Matsumoto T,Seki S,Arakawa T

更新日期：2002-12-01 00:00:00

abstract：:This article [1] is retracted at the request of Editor-in-Chief. ...

journal_title：Digestive diseases and sciences

authors： Zong G,Xu Z,Zhang S,Shen Y,Qiu H,Zhu G,He S,Tao T,Chen X

更新日期：2019-11-11 00:00:00

abstract：:Helicobacter pylori infection has been linked with gastric carcinoma. Epithelial cell proliferation is an indicator of cancer risk. The aim of this study was to assess gastric epithelial cell proliferation before and after eradication therapy and to assess the efficacy of treatment of H. pylori infection using lanzopr...

journal_title：Digestive diseases and sciences

authors： Cahill RJ,Xia H,Kilgallen C,Beattie S,Hamilton H,O'Morain C

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00

abstract：:Endoscopic biopsies are being increasingly utilized to investigate cytokine profiles in normal and diseased intestine. To evaluate the adequacy of mucosal biopsies as a source of cytokine-specific mRNA, we measured their content of interleukin-1 beta (IL-1 beta) and interleukin-2 (IL-2) mRNA by reverse transcription-p...

journal_title：Digestive diseases and sciences

authors： Fukushima K,West G,Fiocchi C

更新日期：1995-07-01 00:00:00

abstract：:Impairment of pancreatic microcirculation has often been advocated as one pathogenic mechanism in necrotizing pancreatitis. In contrast, data on pancreatic capillary perfusion in edematous pancreatitis are scarce. It was the aim of this experimental study to compare changes in pancreatic microcirculation in edematous ...

journal_title：Digestive diseases and sciences

authors： Klar E,Schratt W,Foitzik T,Buhr H,Herfarth C,Messmer K

更新日期：1994-12-01 00:00:00

abstract：AIM:To evaluate the use of health care resources and the associated costs of complex perianal Crohn's disease (CD) from the National Health System perspective. METHODS:We conducted a multicenter, retrospective, observational study in which gastroenterologists from 11 hospitals in the Community of Madrid took part. Dat...

journal_title：Digestive diseases and sciences

authors： Chaparro M,Zanotti C,Burgueño P,Vera I,Bermejo F,Marín-Jiménez I,Yela C,López P,Martín MD,Taxonera C,Botella B,Pajares R,Ponferrada A,Calvo M,Algaba A,Pérez L,Casis B,Maté J,Orofino J,Lara N,García-Losa M,Badia

更新日期：2013-12-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00

abstract：:Intestinal bacterial overgrowth (IBO) has been suggested to play a pathogenic role in patients with nonalcoholic fatty liver disease (NAFLD). Delayed intestinal transit may contribute to IBO development. Ten nondiabetic patients with NAFLD and abnormal liver enzymes were recruited. Ten healthy individuals, matched by ...

journal_title：Digestive diseases and sciences

authors： Soza A,Riquelme A,González R,Alvarez M,Pérez-Ayuso RM,Glasinovic JC,Arrese M

更新日期：2005-06-01 00:00:00

abstract：:We obtained follow-up information on 13 patients who underwent subtotal colectomy for severe idiopathic constipation 19-45 months previously. Stool frequency increased from one bowel movement per 11.5 days before colectomy to 5.3 bowel movements per day after colectomy. Nine patients have required readmissions for abd...

journal_title：Digestive diseases and sciences

authors： Leon SH,Krishnamurthy S,Schuffler MD

更新日期：1987-11-01 00:00:00

abstract：:The wound-healing property of Preparation-H, a widely used over-the-counter hemorrhoidal product was investigated in a randomized, controlled, double-blind trial. Artificial ulcers were created in the rectum of 12 healthy male volunteers and the size of these ulcers followed until complete healing by visual examinatio...

journal_title：Digestive diseases and sciences

authors： Subramanyam K,Patterson M,Gourley WK

更新日期：1984-09-01 00:00:00

abstract：:The development of a fulminant hepatic failure (FHF) model is necessary for evaluating the efficacy of extracorporeal liver support systems. Recognizing the multifaceted functions of the liver, including synthesis and degradation, we investigated blood chemistry, histological findings, and survival rate in D-galactosa...

journal_title：Digestive diseases and sciences

authors： Shito M,Balis UJ,Tompkins RG,Yarmush ML,Toner M

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

journal_title：Digestive diseases and sciences

authors： Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

更新日期：2013-06-01 00:00:00

abstract：:One hundred sixty-two patients chronically ingesting ibuprofen, piroxicam, or naproxen for osteoarthritis, who had abdominal pain and an endoscopically proven gastric ulcer were evaluated for eight weeks in a randomized, double-blind trial comparing misoprostol (200 micrograms four times daily with meals and at bedtim...

journal_title：Digestive diseases and sciences

authors： Jaszewski R,Graham DY,Stromatt SC

更新日期：1992-12-01 00:00:00

abstract：:Colonoscopy is the dominant colorectal cancer screening strategy in the USA. There are no randomized controlled trials completed of screening colonoscopy, but multiple lines of evidence establish that colonoscopy reduces colorectal cancer incidence in both the proximal and distal colon. Colonoscopy is highly operator ...

journal_title：Digestive diseases and sciences

authors： Rex DK

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Percutaneous endoscopic gastrostomy (PEG) is a commonly performed procedure for patients with severe dysphagia leading to malnutrition. Improved knowledge of risk factors for PEG-related complications might decrease patient discomfort and healthcare costs. AIM:The aim of the present study was to investigate...

journal_title：Digestive diseases and sciences

authors： Lee SP,Lee KN,Lee OY,Lee HL,Jun DW,Yoon BC,Choi HS,Kim SH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect on their regeneration. In this study, we examined whether the pre-activate...

journal_title：Digestive diseases and sciences

authors： Arioka Y,Ito H,Ando T,Ogiso H,Hirata A,Hara A,Seishima M

更新日期：2015-06-01 00:00:00

abstract：:The purpose of this study was to establish if estrogen-induced hepatocyte proliferation in vitro involves the cell cycle regulators cyclin D1, p21(Cip1), and p27(Kip1). Male rat hepatocytes were cultured in presence of 17-beta-estradiol (E2) +/- ICI-182780, a pure estrogen antagonist, and [3H]-thymidine, as required. ...

journal_title：Digestive diseases and sciences

authors： Barone M,Ladisa R,Di Leo A,Spano D,Francioso D,Aglio V,Amoruso A,Francavilla A,Iolascon A

更新日期：2006-03-01 00:00:00