Effects of vasoactive intestinal polypeptide (VIP) on lower esophageal sphincter in awake baboons: comparison with glucagon and secretin.

abstract：:A defective epidermal growth factor receptor (EGFR) abrogates adaptation, while overexpression of EGFR or exogenous epidermal growth factor (EGF) enhances adaptation following small bowel resection (SBR). EGFR is predominantly located on the enterocyte basolateral membrane, yet luminal EGF is increased in injured muco...

journal_title：Digestive diseases and sciences

authors： Avissar NE,Wang HT,Miller JH,Iannoli P,Sax HC

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Both 22- and 25-gauge needles are used for endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) of lesions, yet limited data exist on whether either offers an advantage over the other in terms of specimen cellularity and quality. AIM:The aim of this study was to compare sample quality for 22- and...

journal_title：Digestive diseases and sciences

authors： Lee JH,Stewart J,Ross WA,Anandasabapathy S,Xiao L,Staerkel G

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Fibromyalgia (FM) is a disorder characterized by widespread chronic pain as core symptom and a broad range of comorbidities. Despite the prevalence of gastrointestinal (GI) comorbidities in patients with FM, GI functions have rarely been investigated in animal models of FM. AIMS:The purpose of the present s...

journal_title：Digestive diseases and sciences

authors： Uchida M,Kobayashi O,Yoshida M,Miwa M,Miura R,Saito H,Nagakura Y

更新日期：2019-09-01 00:00:00

abstract：:All cases of hepatolithiasis showed features of chronic proliferative cholangitis, and it has been speculated that the atypical glandular proliferation might be a precursor to overt cholangiocarcinoma. Proliferative cell nuclear antigen (PCNA) is a nuclear protein synthesized in the G1/S phase of the cell cycle and th...

journal_title：Digestive diseases and sciences

authors： Lee KT,Sheen PC

更新日期：1999-11-01 00:00:00

abstract：:Congenital gastric outlet anomalies are rarely seen defects resulting from early embryologic development of foregut. We report a case of congenital pyloric outlet anomaly in a 60-year-old man with mild postprandial epigastric discomfort of approximately 3 months' duration. Endoscopic examination of the stomach showed ...

journal_title：Digestive diseases and sciences

authors： Uraz S,Aygün C,Konduk T,Celebi A,Sentürk O,Hülagü S

更新日期：2007-04-01 00:00:00

abstract：:A model for gastric mucosal injury is proposed in which a key pathogenetic event is the disruption in the normal relationships among several circadian rhythms of gastric function. In the rat a circadian rhythm in acid secretion was found to be out of phase with a circadian rhythm in gastric pepsin secretion, another a...

journal_title：Digestive diseases and sciences

authors： Moore JG,Larsen KR,Barattini P,Dayton MT

更新日期：1994-08-01 00:00:00

abstract：:A new extracorporeal piezoelectric lithotripter was tested for its gallstone disintegration capability. A total of 177 surgically removed gallbladder stones were submitted to piezoelectric shock-wave treatment. Prior to shock-wave application, the diameter, weight, and volume of all the stones and CT density and MR si...

journal_title：Digestive diseases and sciences

authors： Ell C,Kerzel W,Langer H,Heyder N,Foerster E,Domschke W

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Colorectal cancer (CRC) screening with a fecal immunochemical test (FIT) reduces CRC mortality; however, the acceptance rate of a colonoscopy in patients with a positive FIT was not high. The aim of this study was therefore to determine whether a telephone reminder call could increase the acceptance...

journal_title：Digestive diseases and sciences

authors： Cha JM,Lee JI,Joo KR,Shin HP,Park JJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Obesity, gastroesophageal reflux, and Barrett's esophagus have all been linked to esophageal adenocarcinoma. In addition, the decline in Helicobacter pylori (H. pylori) infection in affluent societies has also been suggested to be a major factor in the recent rise in the incidence of esophageal adenocarcinom...

journal_title：Digestive diseases and sciences

authors： Lee YY,Raj SM,Sharif SE,Salleh R,Ayub MC,Graham DY

更新日期：2011-05-01 00:00:00

abstract：:This study was designed to determine the effect of a newly synthesized benzimidazole derivative NC-1300-B on H+, K+-ATPase (proton pump) in the hog gastric mucosa and on the basal gastric acid secretion and necrotizing agent-induced gastric lesions in rats. NC-1300-B inhibited the proton pump in a concentration-depend...

journal_title：Digestive diseases and sciences

authors： Okabe S,Akimoto Y,Yamasaki S,Nagai H

更新日期：1988-11-01 00:00:00

abstract：:The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...

journal_title：Digestive diseases and sciences

authors： Stotzer PO,Fjälling M,Grétarsdóttir J,Abrahamsson H

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVES:To evaluate rate, recurrence, and predictors of gastrointestinal bleeding (GIB) and impact of endoscopy in left ventricular assist device (LVAD) patients. METHODS:This is a cohort study of all patients who received the current-generation continuous-flow HeartMate II LVAD from 2005 to 2013 at our institution...

journal_title：Digestive diseases and sciences

authors： Jabbar HR,Abbas A,Ahmed M,Klodell CT Jr,Chang M,Dai Y,Draganov PV

更新日期：2015-12-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to investigate and compare the specificity, sensitivity, and area under curve (AUC) of the lactulose/mannitol ratio, lactulose/creatinine ratio, and lactulose recovery and their diagnostic value for intestinal permeability assessment within the absorption lactulose/mannitol (L/M...

journal_title：Digestive diseases and sciences

authors： Dastych M,Dastych M Jr,Novotná H,Cíhalová J

更新日期：2008-10-01 00:00:00

abstract：:Interferon-alpha therapy for chronic hepatitis C in special patient populations raises a number of issues. Patients with hemophilia, kidney disease requiring hemodialysis, mixed cryoglobulinemia, HIV infection, and those receiving an allograft share some characteristics that complicate the treatment of hepatitis C vir...

journal_title：Digestive diseases and sciences

authors： Marcellin P,Boyer N,Behamou JP,Erlinger S

更新日期：1996-12-01 00:00:00

abstract：:Low or minimal doses of aspirin are widely used for prevention of cardiovascular diseases. Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation. Less is known about the risk associated with minidose aspirin. Our aim was to assess the possible association of upper gastro...

journal_title：Digestive diseases and sciences

authors： Sapoznikov B,Vilkin A,Hershkovici M,Fishman M,Eliakim R,Niv Y

更新日期：2005-09-01 00:00:00

abstract：:To investigate the pathophysiological basis of Courvoisier's law, the gallbladder size and pliability were measured in chronic calculous cholecystitis with (7 patients) or without (25 patients) common duct obstruction, in periampullary malignancy (6 patients), and in the normal state (3 patients). The duration and lev...

journal_title：Digestive diseases and sciences

authors： Chung RS

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) is a safe and effective way to sample lesions in the gastrointestinal tract. Rapid on-site specimen evaluation (ROSE) improves the accuracy of EUS-FNA. While data suggests that EUS with fine-needle biopsy (EUS-FNB) is effective, it remains unclear...

journal_title：Digestive diseases and sciences

authors： Krishnan K,Dalal S,Nayar R,Keswani RN,Keefer L,Komanduri S

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00

abstract：:Insulinlike growth factor-1 (IGF-1) is an anabolic hormone synthesized by the liver upon stimulation by growth hormone (GH). IGF-1 exerts important effects on renal hemodynamics and renal sodium handling. The bioactivity of this hormone is influenced by its binding proteins (BP) of which IGF-BP3 favors retention in th...

journal_title：Digestive diseases and sciences

authors： Fernández-Rodriguez CM,Prada I,Andrade A,Moreiras M,Guitián R,Aller R,Lledó JL,Cacho G,Quiroga J,Prieto J

更新日期：2001-06-01 00:00:00

abstract：:Despite many studies on pain of functional gastrointestinal disorders (FGID), the pain mechanism of FGID is not well understood, and pain treatment of FGID is not established. Following our former functional dyspepsia (FD) study, we proposed two subgroups of patients with irritable bowel syndrome (IBS), pain and disco...

journal_title：Digestive diseases and sciences

authors： Handa M,Nukina H,Ando K,Kubo C

更新日期：2004-04-01 00:00:00

abstract：:Forty-nine Japanese patients were enrolled in a randomized, placebo-controlled, double-blind trial of alpha-interferon for chronic non-A, non-B hepatitis: 24 patients received 3 million units of recombinant human alpha alpha-interferon (alpha-2a) thrice weekly for eight weeks, and 25 patients received placebo in a sim...

journal_title：Digestive diseases and sciences

authors： Omata M,Ito Y,Yokosuka O,Imazeki F,Tagawa M,Takano S,Hosoda K,Tada M,Ohto M,Ito K

更新日期：1991-09-01 00:00:00

abstract：:Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) has been shown to inhibit the proliferation of gastric cancer cells. A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer. We investigated the influence of PPARgamm...

journal_title：Digestive diseases and sciences

authors： Tahara T,Arisawa T,Shibata T,Nakamura M,Wang F,Maruyama N,Kamiya Y,Nakamura M,Fujita H,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2008-03-01 00:00:00

abstract：:To study the clinicopathologic features of hepatitis C viremic patients negative for hepatitis C antibodies (anti-HCV) by current second-generation assay, we categorized 139 consecutive histologically verified patients with chronic non-A, non-B hepatitis into three groups: 121 (87%) were positive for second-generation...

journal_title：Digestive diseases and sciences

authors： Kao JH,Lai MY,Hwang YT,Yang PM,Chen PJ,Sheu JC,Wang TH,Hsu HC,Chen DS

更新日期：1996-01-01 00:00:00

abstract：:A retrospective multicenter analysis of 652 patients with chronic hepatitis C who have been treated with interferon (IFN) was performed to assess the effects of IFN on the clinical course and development of HCC. During a mean follow-up of 54.8 months, hepatocellular carcinoma (HCC) developed in 7.0% of the patients. T...

journal_title：Digestive diseases and sciences

authors： Takimoto M,Ohkoshi S,Ichida T,Takeda Y,Nomoto M,Asakura H,Naito A,Mori S,Hata K,Igarashi K,Hara H,Ohta H,Soga K,Watanabe T,Kamimura T

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin in AH is unknown. AIMS:To investigate the association between my...

journal_title：Digestive diseases and sciences

authors： Shamseddeen H,Madathanapalli A,Are VS,Shah VH,Sanyal AJ,Tang Q,Liang T,Gelow K,Zimmers TA,Chalasani N,Desai AP

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are widely prescribed to treat gastrointestinal diseases. However, concerns have been raised regarding their long-term use. Gastric acid suppression may decrease iron absorption, and it remains uncertain whether iron-deficiency anemia may result from chronic PPI therapy. AIMS:W...

journal_title：Digestive diseases and sciences

authors： Sarzynski E,Puttarajappa C,Xie Y,Grover M,Laird-Fick H

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires quantification of esophageal eosinophilia. AIMS:The aims of this study were to assess inter- and intraobserver reliability for measuring esophageal eosinophil counts and to validate a novel method of determining tissue eosinophil density using digitized h...

journal_title：Digestive diseases and sciences

authors： Dellon ES,Fritchie KJ,Rubinas TC,Woosley JT,Shaheen NJ

更新日期：2010-07-01 00:00:00

abstract：:Although gastric cancer formation with H. pylori in Mongolian gerbils was recently reported, the same inoculation procedure did not result in cancer formation in other animals such as mice. Disturbed regulation of apoptosis and cell proliferation are known to link the multistep process of carcinogenesis. The present s...

journal_title：Digestive diseases and sciences

authors： Suzuki H,Miyazawa M,Nagahashi S,Mori M,Seto K,Kai A,Suzuki M,Miura S,Ishii H

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:Hepatocyte expression of HBV surface, core, and x antigens (HBsAg, HBcAg and HBxAg), semi-quantitated by immunopathology, were correlated with clinical and virological data in 80 patients with chronic hepatitis B. RESULTS:Seventy patients were HBsAg positive in cytoplasm, 61 were HBcAg positive, including 45 i...

journal_title：Digestive diseases and sciences

authors： Chu CM,Shyu WC,Liaw YF

更新日期：2010-02-01 00:00:00

abstract：:Four patients treated with the herbal medicine syo-saiko-to (xiao-chai-hu-tang) exhibited acute drug-induced liver injury. The latent period was one and a half to three months. All of the patients showed a rise in aminotransferases after readministration or challenge test. The liver histology revealed centrilobular co...

journal_title：Digestive diseases and sciences

authors： Itoh S,Marutani K,Nishijima T,Matsuo S,Itabashi M

更新日期：1995-08-01 00:00:00