Asynchrony in circadian rhythms of gastric function in the rat. A model for gastric mucosal injury.

abstract：BACKGROUND:Flavonoids have been subjected to considerable investigations due to their antioxidant and anti-inflammatory properties. Yet the effects of flavonoids on the ileum and spleen against hepatic ischemia-reperfusion injury have so far not been addressed. AIMS:We aimed to investigate whether micronized purified ...

journal_title：Digestive diseases and sciences

authors： Yildiz F,Terzi A,Coban S,Bitiren M,Celik H,Aksoy N,Ozdogan MK,Cakir H

更新日期：2010-08-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：:The optimal administration of immunosuppressants such as tacrolimus (Tac) for small-for-size (SFS) grafts, where the functional liver mass is small and must regenerate, has not been reported so far. The aim of this study is to clarify the characteristics of Tac metabolism according to liver volume. Seven-week-old male...

journal_title：Digestive diseases and sciences

authors： Morine Y,Shimada M,Torii M,Imura S,Ikegami T,Kanemura H,Arakawa Y,Hanaoka J,Kanamoto M,Nii A,Yamazaki N

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:There is no consensus regarding the benefit of eradicating Helicobacter pylori (H. pylori) infection in patients with functional dyspepsia (FD). We intended to compare the symptom response to H. pylori eradication in FD patients in presence or absence of microscopic duodenitis (MD). METHODS:Patients...

journal_title：Digestive diseases and sciences

authors： Mirbagheri SS,Mirbagheri SA,Nabavizadeh B,Entezari P,Ostovaneh MR,Hosseini SM,Rakhshani N,Safa H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Globus sensation is common, but its pathogenesis is not yet clear. AIMS:Our purpose was to investigate subjective perception of swallowing and esophageal motility by combined multichannel intraluminal impedance and manometry (MII-EM) for patients with globus sensation. METHODS:Combined MII-EM was performed...

journal_title：Digestive diseases and sciences

authors： Chen CL,Yi CH,Liu TT

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The performance characteristics of colonic sensation and motility measurements are unclear. AIM:To compare left colon compliance, tone, and sensation in males and females and to evaluate inter and intra-individual coefficients of variation (COV) in these measurements. METHODS:Data were acquired using stand...

journal_title：Digestive diseases and sciences

authors： Odunsi ST,Camilleri M,Bharucha AE,Papathanasopoulos A,Busciglio I,Burton D,Zinsmeister AR

更新日期：2010-03-01 00:00:00

abstract：:Chronic abdominal wall pain (CAWP) is common and frequently mistaken for visceral pain. We determined the stability of this diagnosis with Main Outcome Measures of: (a) change of pain intensity after local anesthetic-corticosteroid injection, (b) pain relief after three or more months follow-up, and (c) costs of diagn...

journal_title：Digestive diseases and sciences

authors： Greenbaum DS,Greenbaum RB,Joseph JG,Natale JE

更新日期：1994-09-01 00:00:00

abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...

journal_title：Digestive diseases and sciences

authors： Manthey MW,Ross AB,Soergel KH

更新日期：1997-08-01 00:00:00

abstract：:Previous studies have suggested that the cyclic entry of bile into the duodenum during fasting regulates interdigestive patterns of motility by releasing the putative regulatory hormone motilin. Our aim was to determine if cyclic secretion of bile into the duodenum regulates interdigestive myoelectric activity and pla...

journal_title：Digestive diseases and sciences

authors： Hughes SJ,Behrns KE,Sarr MG

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVES:Lifestyle and demographic risk factors for the development of oesophageal adenocarcinoma developing from columnar-lined oesophagus are not well defined. METHODS:Demographic and lifestyle factors, endoscopy and histology reports were extracted from 1,761 subjects from seven UK centres. The associations of co...

journal_title：Digestive diseases and sciences

authors： Gatenby PA,Caygill CP,Ramus JR,Charlett A,Watson A

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The nature and outcomes of infection among patients with cirrhosis in safety-net hospitals are not well described. We aimed to characterize the rate of and risk factors for infection, both present on admission and nosocomial, in this unique population. We hypothesized that infections would be associ...

journal_title：Digestive diseases and sciences

authors： Fricker ZP,Mukthinuthalapati VVPK,Akinyeye S,Chalasani N,Attar BM,Balakrishnan M,Ghabril M,Long MT

更新日期：2021-01-01 00:00:00

abstract：:The Wnt/beta-catenin pathway has been proposed as promoting intestinal stem cell division. Wnt ligands activate cytoplasmic beta-catenin and increase nuclear translocation of beta-catenin that binds to the Tcf-4 transcription factor. The aim of this study was to investigate beta-catenin expression in the stem cell reg...

journal_title：Digestive diseases and sciences

authors： Camac KS,Thompson FM,Cummins AG

更新日期：2007-05-01 00:00:00

abstract：:This paper reviews recent clinical evidence that suggests that aspirin prophylaxis against cardiac and cerebral vascular ischemia is associated with significant gastrointestinal complications. The clinical and experimental evidence to confirm the role of risk factors of concomitant use of nonsteroidal anti-inflammator...

journal_title：Digestive diseases and sciences

authors： Leung FW

更新日期：2008-10-01 00:00:00

abstract：:Development of type 1 insulin-dependent diabetes mellitus has been recently reported in patients who underwent interferon-alpha (IFN-alpha) therapy because of chronic viral hepatitis. Furthermore IFN-alpha seems to be involved in the immunological events that lead to beta-cell destruction and development of type 1 dia...

journal_title：Digestive diseases and sciences

authors： di Cesare E,Previti M,Russo F,Brancatelli S,Ingemi MC,Scoglio R,Mazzù N,Cucinotta D,Raimondo G

更新日期：1996-08-01 00:00:00

abstract：:The relationship between the GOT/GPT ratio in nonviral liver disorders and underlying physical condition and life-style were evaluated. The subjects were 12,808 male railway company workers who underwent an annual health checkup. Nonviral liver disorders were defined as elevated transaminases (GOT > 76 IU/liter or GPT...

journal_title：Digestive diseases and sciences

authors： Mukai M,Ozasa K,Hayashi K,Kawai K

更新日期：2002-03-01 00:00:00

abstract：:Seven subjects were given one day's treatment with full doses of either aspirin, ibuprofen, or placebo, and then their stomachs were washed out three times at intervals of 10 min, for five successive days. The blood in the recoveries was estimated chemically. After compensating for gastric emptying, the rate of bleedi...

journal_title：Digestive diseases and sciences

authors： Hunt JN

更新日期：1979-07-01 00:00:00

abstract：:Several epidemiological studies have demonstrated a close association between Helicobacter pylori infection and carcinoma of the mid- or distal stomach. If this can be shown to be a causal association, eradication of the organism may prevent later development of cancer. Several mechanisms have been proposed by which H...

journal_title：Digestive diseases and sciences

authors： Hahm KB,Lee KJ,Kim JH,Cho SW,Chung MH

更新日期：1998-09-01 00:00:00

abstract：:Cyclin D1 plays an important role in the multi-step process of gastrointestinal tumorigenesis. We hypothesize that normal enterocytes over-expressing cyclin D1 will demonstrate a transformed phenotype. The nontumorigenic intestinal epithelial cell line, IEC-18, was transfected with the vector pMV7-CCND1, encoding cycl...

journal_title：Digestive diseases and sciences

authors： Kazanov D,Shapira I,Pick M,Kolker O,Liberman E,Deutsch V,Strier L,Dvory-Sobol H,Kunik T,Arber N

更新日期：2003-07-01 00:00:00

abstract：:There is a growing body of experimental and clinical evidence to suggest that oral or rectal administration of 5-ASA or 5-ASA conjugates is associated with significant adverse side effects including pancreatitis, hepatitis, and renal toxicity. The objective of this study was to assess the ability of 5-ASA to interact ...

journal_title：Digestive diseases and sciences

authors： Grisham MB,Ware K,Marshall S,Yamada T,Sandhu IS

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic liver disease and is considered a profibrotic mediator due to its proliferative effect on cultured HSCs and ability to degrade normal liver matrix. Although associ...

journal_title：Digestive diseases and sciences

authors： Radbill BD,Gupta R,Ramirez MC,DiFeo A,Martignetti JA,Alvarez CE,Friedman SL,Narla G,Vrabie R,Bowles R,Saiman Y,Bansal MB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is an established causal factor for non-cardia gastric cancer. H. pylori negative gastric cancer prevalence among US patients is unclear. METHODS:This retrospective cohort study examined H. pylori prevalence among consecutive patients with incident non-cardia gastric adenocarci...

journal_title：Digestive diseases and sciences

authors： Nguyen TH,Mallepally N,Hammad T,Liu Y,Thrift AP,El-Serag HB,Tan MC

更新日期：2020-08-01 00:00:00

abstract：:Over the past two decades, evidence has accumulated to challenge the traditional view that cardiac mucosa, which is comprised exclusively of mucus glands, is the normal lining of the most proximal portion of the stomach (the gastric cardia). There is now considerable evidence to suggest that cardiac mucosa develops as...

journal_title：Digestive diseases and sciences

authors： Spechler SJ

更新日期：2018-08-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:Of 112 patients with peptic ulcer disease examined for oral carriage of Candida, 66 (59%) were carriers. Candida carriage was associated with blood group O (P < 0.05) and, independently, with nonsecretion of blood group antigens (P < 0.01). For each subject, the presence or absence of yeasts was found to be a constant...

journal_title：Digestive diseases and sciences

authors： Burford-Mason AP,Willoughby JM,Weber JC

更新日期：1993-08-01 00:00:00

abstract：:Some endoscopic trainees find it difficult to manipulate an endoscope's controls, possibly due to small hand size. To assess this, a survey was mailed to all gastroenterology fellows in the US. Two hundred twenty-seven of 1,295 (17.5%) fellows responded. Median surgical glove size was 7.5. Ninety-three respondents (41...

journal_title：Digestive diseases and sciences

authors： Cohen DL,Naik JR,Tamariz LJ,Madanick RD

更新日期：2008-07-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：:The results of 88 consecutive small-bowel enemas were compared retrospectively with the results of 52 routine small-bowel series and 50 barium enemas done in the same patients. Ninety-six percent of the diagnoses made by small-bowel enema were correct, as compared to only 65% made by routine small-bowel series. The in...

journal_title：Digestive diseases and sciences

authors： Gurian L,Jendrzejewski J,Katon R,Bilbao M,Cope R,Melnyk C

更新日期：1982-12-01 00:00:00

abstract：:Inadequate vegetable intake appears to increase colon cancer risk. Since genetic variation in taste influences vegetable preference, we tested associations between bitterness of 6-n-propylthiouracil (PROP), a measure of taste genetics, and number of colonic polyps, a measure of colon cancer risk, in 251 men who underw...

journal_title：Digestive diseases and sciences

authors： Basson MD,Bartoshuk LM,Dichello SZ,Panzini L,Weiffenbach JM,Duffy VB

更新日期：2005-03-01 00:00:00

abstract：:As immunosuppressive agents, corticosteroids may be considered an appropriate treatment for primary biliary cirrhosis, even if bone loss and other side effects may occur. We studied biliary lipid metabolism in 10 nonicteric patients, with histologically proven primary biliary cirrhosis (stage I-IV). We administered me...

journal_title：Digestive diseases and sciences

authors： Mazzella G,Fusaroli P,Pezzoli A,Azzaroli F,Mazzeo C,Zambonin L,Simoni P,Festi D,Roda E

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIM:Diabetes is the main cause of gastroparesis accompanying decreased neuronal nitric oxide synthase (nNOS) in myenteric ganglia of the stomach. Decreased nNOS expression in the stomach also results from defects in apolipoprotein E (ApoE), which is secreted by astrocytes and has neuroprotective effects ...

journal_title：Digestive diseases and sciences

authors： Fukuhara S,Masaoka T,Nishimura S,Nakamura M,Matsuzaki J,Tsugawa H,Miyoshi S,Mori H,Kawase S,Shibata S,Okano H,Kanai T,Suzuki H

更新日期：2017-12-01 00:00:00